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Article
Limited HIV-associated neuropathologies and lack of immune activation in sub-saharan African individuals with late-stage subtype C HIV-1 infection
Although previous studies have suggested that subtype B HIV-1 proviruses in the brain are associated with physiological changes and immune activation accompanied with microgliosis and astrogliosis, and indicat...
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Article
Open AccessImproved efficacy and safety of zanubrutinib versus ibrutinib in patients with relapsed/refractory chronic lymphocytic leukemia (R/R CLL) in China: a subgroup of ALPINE
Chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) has different epidemiology in Chinese vs. Western patients, but there are few studies of CLL/SLL in large populations of Chinese patients. ALPI...
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Article
Open AccessSolvent engineering for scalable fabrication of perovskite/silicon tandem solar cells in air
Perovskite/silicon tandem solar cells hold great promise for realizing high power conversion efficiency at low cost. However, achieving scalable fabrication of wide-bandgap perovskite (~1.68 eV) in air, withou...
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Article
Open AccessAdipose stem cells-derived small extracellular vesicles transport Thrombospondin 1 cargo to promote insulin resistance in gestational diabetes mellitus
Gestational diabetes mellitus (GDM) is a highly prevalent disease and poses a significant risk to the health of pregnant women. Abdominal adipose tissue (AT) contributes to insulin resistance (IR) associated w...
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Article
Open AccessThe bi-directional relationships between diversified leisure activity participation and cognitive function in older adults in China: separating between-person effects from within-person effects
To examine the bi-directorial association between diversified leisure activity participation and cognitive function over a 7-year period.
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Article
Identification and Expression Analysis of Soybean (Glycine max L.) Dynamin Genes Reveal Their Involvements in Plant Development and Stress Response
Dynamin and dynamin-related proteins (DRPs) are large GTPases that are vital for cytokinesis, endocytosis and multiple biological processes. However, knowledge of the DRP gene family in soybean (Glycine max L.), ...
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Article
Genome-Wide Analysis of Soybean Vacuolar Processing Enzyme Gene Family Reveals Their Roles in Plant Development and Response to Stress Conditions
Vacuolar processing enzymes (VPEs) are important proteases for the processing and maturation of vacuolar proteins. The VPEs in model plant Arabidopsis have been well researched. However, less is known about th...
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Article
Sequential haplo-identical conditioning transplant regimen for pediatric patients with relapsed or refractory hemophagocytic lymphohistiocytosis
Allogeneic hematopoietic stem cell transplantation (HSCT) currently stands as the sole remedy for individuals afflicted with hemophagocytic lymphohistiocytosis (HLH). In this study, we retrospectively evaluate...
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Article
Open AccessIntegrated transcriptome and metabolome analysis reveals anthocyanin biosynthesis mechanisms in pepper (Capsicum annuum L.) leaves under continuous blue light irradiation
Different metabolic compounds give pepper leaves and fruits their diverse colors. Anthocyanin accumulation is the main cause of the purple color of pepper leaves. The light environment is a critical factor aff...
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Article
Open AccessCorrection: Silencing of CD147 inhibits cell proliferation, migration, invasion, lipid metabolism dysregulation and promotes apoptosis in lung adenocarcinoma via blocking the Rap1 signaling pathway
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Article
Open AccessTargeting vulnerable microcircuits in the ventral hippocampus of male transgenic mice to rescue Alzheimer-like social memory loss
Episodic memory loss is a prominent clinical manifestation of Alzheimer’s disease (AD), which is closely related to tau pathology and hippocampal impairment. Due to the heterogeneity of brain neurons, the spec...
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Article
Design and characterization of a 90 GHz CMB TES bolometer
The transition-edge sensor (TES) as a type of low-temperature superconducting detector offers superior sensitivity due to its low thermal noise. In this work, we present a prototype TES bolometer designed for ...
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Article
Open AccessLASS2 suppresses metastasis in multiple cancers by regulating the ferroptosis signalling pathway through interaction with TFRC
As a key enzyme in ceramide synthesis, longevity assurance homologue 2 (LASS2) has been indicated to act as a tumour suppressor in a variety of cancers. Ferroptosis is involved in a variety of tumour processes...
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Article
Open AccessIncreased susceptibility to new-onset atrial fibrillation in diabetic women with poor sleep behaviour traits: findings from the prospective cohort study in the UK Biobank
Diabetic individuals often encounter various sleep-related challenges. Although the association between sleep duration and atrial fibrillation (AF) have been explored, the association of other sleep traits wit...
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Article
Open AccessMulticompartmental coacervate-based protocell by spontaneous droplet evaporation
Hierarchical compartmentalization, a hallmark of both primitive and modern cells, enables the concentration and isolation of biomolecules, and facilitates spatial organization of biochemical reactions. Coacerv...
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Article
A Thermal Kinetic Inductance Detector Pixel Design for CMB Polarization Observations at 90/150 GHz Bands
The highly sensitive millimeter-wave telescope is an important tool for accurate measurement of cosmic microwave background (CMB) radiation, and its core component is a detector array located in a cryogenic fo...
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Article
The Function of Circular RNAs in Myocardial Ischemia–Reperfusion Injury: Underlying Mechanisms and Therapeutic Advancement
Myocardial ischemia reperfusion injury (MIRI) represents a prevalent and severe cardiovascular condition that arises primarily after myocardial infarction recanalization, cardiopulmonary bypass surgery, and bo...
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Article
Open AccessPrognostic impact of oral microbiome on survival of malignancies: a systematic review and meta-analysis
Recent studies have shown that there exists a significant correlation between oral microbiome and the occurrence of malignancies. However, the prognostic significance of oral microbiome for cancer patients rem...
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Article
Scoring model based on cardiac CT and clinical factors to predict early good mitral valve repair in rheumatic mitral disease
We aimed to evaluate the mitral valve calcification and mitral structure detected by cardiac computed tomography (cardiac CT) and establish a scoring model based on cardiac CT and clinical factors to predict e...
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Article
Open AccessHigh glucose-induced injury in human umbilical vein endothelial cells is alleviated by vitamin D supplementation through downregulation of TIPE1
Diabetes mellitus (DM) and its associated vascular complications have become a worldwide health concern. The effects and mechanism of vitamin D supplementation on endothelial function under high glucose condit...
