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Article
Germline AIP variants in sporadic young acromegaly and pituitary gigantism: clinical and genetic insights from a Han Chinese cohort
Variants in the Aryl hydrocarbon receptor-interacting protein (AIP) gene have been identified in sporadic acromegaly and pituitary gigantism, especially in young patients, with a predisposition to aggressive clin...
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Article
Open AccessNicotinamide protects against diabetic kidney disease through regulation of Sirt1
To investigate the effect of nicotinamide (Nam) on diabetic kidney disease (DKD) in mice and explore its mechanism.
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Article
Open AccessAuthor Correction: Identification of recurrent USP48 and BRAF mutations in Cushing’s disease
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Article
The recovery time of hypothalamic-pituitary-adrenal axis after curative surgery in Cushing’s disease and its related factor
Patients with Cushing’s disease (CD) experienced transient central adrenal insufficiency (CAI) after successful surgery. However, the reported recovery time of hypothalamic-pituitary-adrenal (HPA) axis varied ...
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Article
Open AccessGlobal changes in chromatin accessibility and transcription in growth hormone-secreting pituitary adenoma
Growth hormone-secreting pituitary adenoma (GHPA) is an insidious disease with persistent hypersecretion of growth hormone and insulin-like growth factor 1, causing increased morbidity and mortality. Previous ...
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Article
The hypothalamic-pituitary-gonad axis in male Cushing’s disease before and after curative surgery
Gonadal and sexual disturbances are commonly encountered in patients with Cushing’s disease. Nevertheless, the prevalence of hypogonadism in male Cushing’s disease, the risk factors as well as the recovery tim...
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Article
Radiomics analysis allows for precise prediction of silent corticotroph adenoma among non-functioning pituitary adenomas
To predict silent corticotroph adenomas (SCAs) among non-functioning pituitary adenomas preoperatively using noninvasive radiomics.
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Article
Global regularity of the 2D generalized MHD equations with velocity dam** and Laplacian magnetic diffusion
In this paper, we focus on the global regularity of smooth solutions for 2D incompressible generalized magnetohydrodynamics equations with a velocity dam** term and the standard Laplacian magnetic diffusion....
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Article
Open AccessPS-341 alleviates chronic low-grade inflammation and improves insulin sensitivity through the inhibition of TM4 (UBAC2) degradation
The TM4 (UBAC2) protein, which contains 4 transmembrane domains and one ubiquitin binding domain, is mainly expressed in cell and nuclear membranes. The current research aimed to explore the role of TM4 in metabo...
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Article
Machine learning in predicting early remission in patients after surgical treatment of acromegaly: a multicenter study
Accurate prediction of postoperative remission is beneficial for effective patient-physician communication in acromegalic patients. This study aims to train and validate machine learning prediction models for ...
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Article
Large time behaviour of solutions to the 3D Navier–Stokes equations with dam**
In this paper, we consider large time behaviour of solutions to the 3D Navier–Stokes equations with dam** term \(|u|^{\beta -1}u\) | u | β - 1 u ( \(\beta \ge 1\) β ≥ 1 ). For $$\beta >\frac{7}{...
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Article
Open AccessThe association of erythrocyte sedimentation rate, high-sensitivity C-reactive protein and diabetic kidney disease in patients with type 2 diabetes
To evaluate the association between high-sensitivity C-reactive protein (hsCRP) and erythrocyte sedimentation rate (ESR), and diabetic kidney disease (DKD) in patients with type 2 diabetes mellitus (T2DM).
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Article
RETRACTED ARTICLE: Local Well-Posedness for the Incompressible Full Magneto-Micropolar System with Vacuum
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Article
Local well-posedness for the incompressible full magneto-micropolar system with vacuum
In this paper, a full incompressible magneto-micropolar system is investigated. We prove the local well-posedness of strong solutions to the full system with vacuum. Moreover, previous compatibility conditions...
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Article
Regularity Criteria for a Ginzburg–Landau–Navier–Stokes in a Bounded Domain
In this work, we prove some regularity criteria for a Ginzburg–Landau–Navier–Stokes system with the Coulomb gauge in a bounded domain \(\Omega \subset {\mathbb {R}}^3\,\)Ω⊂R3.
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Article
Surgical outcomes and predictors of glucose metabolism alterations for growth hormone-secreting pituitary adenomas: a hospital-based study of 151 cases
The surgical outcome on glucose metabolism in acromegaly patients is not fully understood. We aimed to investigate the impact of surgery on glucose metabolism and identify key factors that influence alteration...
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Article
Open AccessIdentification of recurrent USP48 and BRAF mutations in Cushing’s disease
Cushing’s disease results from corticotroph adenomas of the pituitary that hypersecrete adrenocorticotropin (ACTH), leading to excess glucocorticoid and hypercortisolism. Mutations of the deubiquitinase gene USP8
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Article
Open AccessRecombinant SFRP5 protein significantly alleviated intrahepatic inflammation of nonalcoholic steatohepatitis
Secreted frizzled-related protein 5 (SFRP5) is an anti-inflammatory adipokine modulating metabolism dysfunction. This study aims to observe the effect of recombinant SFRP5 protein on nonalcoholic steatohepatit...
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Article
Open AccessLineage conversion of mouse fibroblasts to pancreatic α-cells
α-cells, which synthesize glucagon, also support β-cell survival and have the capacity to transdifferentiate into β-cells. However, the role of α-cells in pathological conditions and their putative clinical ap...
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Article
Open AccessClinical features of patients with pituitary stalk thickening: a review of 159 cases from one medical center
Pituitary stalk thickening (PST) used as an imaging diagnosis plays a major role in diagnosis and treatment of the hypothalamus and pituitary disease at an early stage. Up until now, several lines of systemati...
