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  1. No Access

    Article

    Clinical presentations of acquired comitant esotropia in 5–35 years old Japanese and digital device usage: a multicenter registry data analysis study

    To describe clinical presentations of acquired comitant esotropia and digital device use in children, adolescents, and young adults without neurological problems.

    Hirohito Iimori, Sachiko Nishina, Osamu Hieda in Japanese Journal of Ophthalmology (2023)

  2. Article

    Open Access

    Identification of SARS-CoV-2 Mpro inhibitors containing P1’ 4-fluorobenzothiazole moiety highly active against SARS-CoV-2

    COVID-19 caused by SARS-CoV-2 has continually been serious threat to public health worldwide. While a few anti-SARS-CoV-2 therapeutics are currently available, their antiviral potency is not sufficient. Here, ...

    Nobuyo Higashi-Kuwata, Kohei Tsuji, Hironori Hayashi, Haydar Bulut in Nature Communications (2023)

  3. Article

    Open Access

    A deletion in the Ctns gene causes renal tubular dysfunction and cystine accumulation in LEA/Tohm rats

    The Long-Evans Agouti (LEA/Tohm) rat has recently been established as a new rat model of type 2 diabetes. The onset of diabetes mellitus was observed only in male LEA/Tohm rats; however, urinary glucose appear...

    Yukiko Shimizu, Rieko Yanobu-Takanashi, Kenta Nakano, Kenji Hamase in Mammalian Genome (2019)

  4. No Access

    Article

    Role of G protein-regulated inducer of neurite outgrowth 3 (GRIN3) in β-arrestin 2-Akt signaling and dopaminergic behaviors

    The G protein-regulated inducer of neurite growth (GRIN) family has three isoforms (GRIN1-3), which bind to the Gαi/o subfamily of G protein that mediate signal processing via G protein-coupled receptors (GPCR...

    Yasumasa Mototani, Tadashi Okamura in Pflügers Archiv - European Journal of Phys… (2018)

  5. Article

    Open Access

    Molecular gas thermometry on acetylene using dual-comb spectroscopy: analysis of rotational energy distribution

    We propose and demonstrate a novel method for temperature determination using dual-comb spectroscopy and a novel analysis technique, “Rotational-state Distribution Thermometry: RDT.” We obtained the spectral p...

    Yukiko Shimizu, Sho Okubo, Atsushi Onae, Koichi M. T. Yamada in Applied Physics B (2018)

  6. No Access

    Article

    Serum level of soluble triggering receptor expressed on myeloid cells-1 as a biomarker of disease activity in relapsing polychondritis

    We aimed to identify a serum biomarker for evaluating the disease activity of relapsing polychondritis (RP).

    Tomoo Sato, Yoshihisa Yamano, Utano Tomaru, Yukiko Shimizu in Modern Rheumatology (2013)

  7. Article

    Open Access

    Functional impairment of Tax-specific but not cytomegalovirus-specific CD8+ T lymphocytes in a minor population of asymptomatic human T-cell leukemia virus type 1-carriers

    Human T-cell leukemia virus type 1 (HTLV-1) causes adult T-cell leukemia (ATL) and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in a small percentage of infected individuals. ATL is ofte...

    Ayako Takamori, Atsuhiko Hasegawa, Atae Utsunomiya, Yasuhiro Maeda in Retrovirology (2011)

  8. Article

    Open Access

    The roles of innate and acquired immune responses on HTLV-I infection

    Mari Kannagi, Shuichi Kinpara, Atsuhiko Hasegawa, Ayako Takamori in Retrovirology (2011)

  9. Article

    Open Access

    Clinical subtype of HAM/TSP based on clinical course and laboratory findings

    Yoshihisa Yamano, Tomoo Sato, Natsumi Araya, Naoko Yagishita in Retrovirology (2011)

  10. Article

    Open Access

    Functional impairment of Tax-specific but not CMV-specific CTLs in a minor population of asymptomatic HTLV-1-carriers

    Atsuhiko Hasegawa, Ayako Takamori, Atae Utsunomiya, Yasuhiro Maeda in Retrovirology (2011)

  11. Article

    Radiation unlikely to be responsible for high cancer rates among distal Hiroshima A-bomb survivors

    Eric J. Grant, Yukiko Shimizu in Environmental Health and Preventive Medici… (2009)

  12. No Access

    Chapter and Conference Paper

    The Offspring of Atomic Bomb Survivors: Cancer and Non-Cancer Mortality and Cancer Incidence

    The Radiation Effects Research Foundation (RERF) has conducted several studies of the potential impact of genetic effects on the mortality and cancer incidence among about 41 000 offspring born to atomic bomb ...

    Akihiko Suyama, Shizue Izumi, Kojiro Koyama, Ritsu Sakata in Radiation Health Risk Sciences (2009)

  13. No Access

    Article

    Optimization of Ga(In)NAs thin film growth by atomic hydrogen-assisted molecular beam epitaxy

    The effect of growth temperature on the crystal quality and optical properties of Ga(In)NAs films was investigated over a range of 340 ∼ 520 °C. We found that Ga(In)NAs films fabricated at lower growth tempera...

    Yukiko Shimizu, Naoya Miyashita, Yoshitaka Okada in MRS Online Proceedings Library (2006)

  14. No Access

    Article

    The effect of vaginal delivery on the pelvic floor

    This study was undertaken to determine the effects of vaginal deliveries on anorectal function, and to analyze the possible clinical, physiological, and radiological risk factors predisposing to damage of the ...

    Akira Tsunoda, Miki Shibusawa, Goichi Kamiyama, Mitsuo Kusano in Surgery Today (1999)

  15. No Access

    Chapter

    Lactoferrin and Interleukin-6 Interaction in Amniotic Infection

    Lactoferrin (Lf) has been found in most biological fluids including amniotic fluid and cervical mucoids in pregnant women, and released from neutrophils in response to the inflammation. As Lf possesses antimic...

    Katufumi Otsuki, Aki Yoda, Yoshiro Toma, Yukiko Shimizu in Advances in Lactoferrin Research (1998)

  16. No Access

    Chapter and Conference Paper

    Identification and Characterization of a Ligand for Receptor Protein-Tyrosine Kinase HTK Expressed in Hematopoietic Cells

    HTK is a receptor tyrosine kinase (RTK) which belongs to the Eph subfamily of RTK. Using a BlAcore, a surface plasmon resonance detection system, it was determined that a colon cancer cell line C-1 expressed H...

    Seiji Sakano, Atsushi Iwama, Akira Ito, Chihiro Kato in Bone Marrow Transplantation (1996)

  17. No Access

    Article

    Variable interferon productivity of vero cells

    Seiya Kohno, Masayoshi Kohase, Hiroko Sakata in Archiv für die gesamte Virusforschung (1972)