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  1. Article

    Open Access

    RAISING is a high-performance method for identifying random transgene integration sites

    Both natural viral infections and therapeutic interventions using viral vectors pose significant risks of malignant transformation. Monitoring for clonal expansion of infected cells is important for detecting ...

    Yusaku Wada, Tomoo Sato, Hiroo Hasegawa, Takahiro Matsudaira in Communications Biology (2022)

  2. Article

    Open Access

    Clinical course of neurogenic bladder dysfunction in human T-cell leukemia virus type-1-associated myelopathy/tropical spastic paraparesis: a nationwide registry study in Japan

    Most patients with human T-cell leukemia virus type 1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) develop neurogenic bladder dysfunction. However, longitudinal changes and treatment effects re...

    Naoki Iijima, Junji Yamauchi, Naoko Yagishita in Orphanet Journal of Rare Diseases (2021)

  3. Article

    Open Access

    Creation and validation of a bladder dysfunction symptom score for HTLV-1-associated myelopathy/tropical spastic paraparesis

    Urinary dysfunction is one of the main features of human T-cell leukemia virus type 1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). However, a comprehensive assessment of the severity is diffic...

    Natsuko Yamakawa, Naoko Yagishita, Tomohiro Matsuo in Orphanet Journal of Rare Diseases (2020)

  4. Article

    Open Access

    Real-world clinical course of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in Japan

    As human T-cell leukemia virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a rare chronic neurological disease, large scale studies to collect continuous clinical data have ...

    Shuntaro Tsutsumi, Tomoo Sato, Naoko Yagishita in Orphanet Journal of Rare Diseases (2019)

  5. Article

    Publisher Correction: Fgf10 is essential for limb and lung formation

    In the version of the paper initially published, Fig. 5a was inadvertently duplicated and presented as both Fig. 5a and 5f, and the correct image for Fig. 5f was omitted. Images of the original and corrected f...

    Keisuke Sekine, Hideyo Ohuchi, Masanori Fujiwara, Masahiro Yamasaki in Nature Genetics (2019)

  6. Article

    Effectiveness of Daily Prednisolone to Slow Progression of Human T-Lymphotropic Virus Type 1-Associated Myelopathy/Tropical Spastic Paraparesis: A Multicenter Retrospective Cohort Study

    Millions of people are infected with human T-lymphotropic virus type 1 (HTLV-1) worldwide; notable endemic areas include Brazil, the Caribbean islands, Iran, and Japan. A small number of those infected develop...

    Ariella L. G. Coler-Reilly, Tomoo Sato, Toshio Matsuzaki in Neurotherapeutics (2017)

  7. Article

    Open Access

    Nation-wide epidemiological study of Japanese patients with rare viral myelopathy using novel registration system (HAM-net)

    At least one million people are infected with human T-lymphotropic virus type 1 (HTLV-1) in Japan, a small percentage of whom develop HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) or adul...

    Ariella L. G. Coler-Reilly, Naoko Yagishita in Orphanet Journal of Rare Diseases (2016)

  8. Article

    Open Access

    HAM-net national patient registration system reveals details of how Japanese patients with HTLV-1-associated myelopathy/tropical spastic paraparesis progress over time

    Ariella Coler-Reilly, Naoko Yagishita, Tomoo Sato, Natsumi Araya in Retrovirology (2015)

  9. Article

    Open Access

    Characteristics of HAM/TSP after kidney transplantation from HTLV-1 positive living donors

    Miyuna Kimura, Junji Yamauchi, Hideki Taisho, Tomoo Sato, Naoko Yagishita in Retrovirology (2015)

  10. Article

    Open Access

    Evaluation of clinical outcome measures for HAM/TSP

    Takayuki Kikuchi, Aika Sawabe, Yui Negishi, Airi Noda, Yuji Hirai in Retrovirology (2015)

  11. Article

    Open Access

    Patient satisfaction survey for HAM-net registrants

    Kentaro Sato, Takayuki Kikuchi, Miyuna Kimura, Midori Komita in Retrovirology (2015)

  12. Article

    HTLV-1 Tax induces Th1 master regulator T-bet and thus IFN-γ in CD4+CCR4+ T-cells of virus-associated myelopathy patients

    Natsumi Araya, Tomoo Sato, Utano Tomaru, Ariella Coler-Reilly in Retrovirology (2015)

  13. Article

    Open Access

    Humanized anti CCR4 antibody KW0761 targets HTLV-1 infected CD4+ CCR4+ and CD8+CCR4+ T cells to treat HAM/TSP

    Yoshihisa Yamano, Junji Yamauchi, Ariella Coler-Reilly, Tomoo Sato in Retrovirology (2015)

  14. Article

    Open Access

    CXCL10 and neopterin in CSF are candidate prognostic biomarkers for HTLV-1-associated myelopathy/tropical spastic paraparesis

    Yoshihisa Yamano, Tomoo Sato, Hitoshi Ando, Natsumi Araya, Naoko Yagishita in Retrovirology (2014)

  15. Article

    Open Access

    Nation-wide epidemiological study in Japan on HTLV-1 associated myelopathy/tropical spastic paraparesis using HAM-net, a novel patient registration system

    Ariella LG Coler-Reilly, Michiyo Hashimoto, Naoko Yagishita, Tomoo Sato in Retrovirology (2014)

  16. Article

    Open Access

    Virus-induced CXCL10-CXCR3 positive feedback loop via astrocytes is critical for maintaining chronic inflammatory lesions in HAM/TSP

    Tomoo Sato, Hitoshi Ando, Utano Tomaru, Mari Yoshida, Atae Utsunomiya in Retrovirology (2014)

  17. Article

    Open Access

    Vulnerability to traumatic stress in fibromyalgia patients: 19 month follow-up after the great East Japan disaster

    The aim of this study was to investigate vulnerability and long-term influence of traumatic stress caused by the Great East Japan Disaster which occurred on March 11, 2011, in patients with fibromyalgia, which...

    Chie Usui, Kotaro Hatta, Satoko Aratani, Naoko Yagishita in Arthritis Research & Therapy (2013)

  18. Article

    The Japanese version of the modified ACR Preliminary Diagnostic Criteria for Fibromyalgia and the Fibromyalgia Symptom Scale: reliability and validity

    The aim of this study is to investigate the reliability and validity of the Japanese version of the modified American College of Rheumatology (ACR) Preliminary Diagnostic Criteria for Fibromyalgia (mACR 2010-J...

    Chie Usui, Kotaro Hatta, Satoko Aratani, Naoko Yagishita in Modern Rheumatology (2013)

  19. Article

    Open Access

    SPACIA1/SAAL1: a newly identified gene associated with aberrant proliferation of synovial fibroblasts

    Tomoo Sato, Ryoji Fujii, Koji Konomi, Naoko Yagishita in Arthritis Research & Therapy (2012)

  20. Article

    Open Access

    Importance of E3 ubiquitin ligase Synoviolin in fibrogenesis

    Naoko Yagishita, Daisuke Hasegawa, Satoko Aratani in Arthritis Research & Therapy (2012)

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