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Article
High-field dielectric properties and high-power performance of Fe-modified PZN–PMS–PZT piezoelectric ceramics
In this work, the 0.04Pb(Zn1/3Nb2/3)O3-0.05Pb(Mn1/3Sb2/3)O3–xPbZrO3–(0.91−x)PbTiO3 + ymol%Fe2O3 (xPZ-PZNMST + y%Fe; x = 0.440–0.460, y = 0.00–0.15) piezoelectric ceramics were synthesized by solid-state reaction ...
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Article
Open AccessNovel biphasic mechanism of the canonical Wnt signalling component PYGO2 promotes cardiomyocyte differentiation from hUC-MSCs
Human umbilical cord–derived mesenchymal stem cells (hUC-MSCs) are used to regenerate the myocardium during cardiac repair after myocardial infarction. However, the regulatory mechanism underlying their abilit...
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Article
High Piezoelectric Performance and Cost-Effective Pb(Mn1/3Nb2/3)O3-Pb(Zr,Ti)O3 Piezoelectric Ceramics
High-power ultrasonic transducers need piezoelectric ceramics with a high piezoelectric coefficient, d33, high quality factor, Qm, large coercivity field, EC, high Curie temperature TC , etc, so that they can wor...
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Article
AKUPP: attention-enhanced joint propagation of knowledge and user preference for recommendation systems
As knowledge graphs have attracted enormous attention from researchers, much effort has been invested in recommendation systems to mine user preferences effectively. In particular, knowledge graphs, which conv...
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Article
Overexpression of PYGO1 promotes early cardiac lineage development in human umbilical cord mesenchymal stromal/stem cells by activating the Wnt/β-catenin pathway
Cardiovascular disease still has the highest mortality. Gene‐modified mesenchymal stromal/stem cells could be a promising therapy. Pygo plays an important role in embryonic development and regulates life activiti...
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Article
An improved hybrid bream derived from a hybrid lineage of Megalobrama amblycephala (♀)×Culter alburnus (♂)
Distant hybridization is an important technique in fish genetic breeding. In this study, based on the establishment of an allodiploid fish lineage (BT, 2n=48, F1–F6) derived from distant hybridization between fem...
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Article
Open AccessBVES downregulation in non-syndromic tetralogy of fallot is associated with ventricular outflow tract stenosis
BVES is a transmembrane protein, our previous work demonstrated that single nucleotide mutations of BVES in tetralogy of fallot (TOF) patients cause a downregulation of BVES transcription. However, the relationsh...
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Article
Open AccessIdentification of zebrafish magnetoreceptor and cryptochrome homologs
Magnetoreception is essential for magnetic orientation in animal migration. The molecular basis for magnetoreception has recently been elucidated in fruitfly as complexes between the magnetic receptor magnetor...
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Article
Open AccessAtorvastatin treatment improves effects of implanted mesenchymal stem cells: meta-analysis of animal models with acute myocardial infarction
Previous studies reported that Atorvastatin (ATOR) can improve the efficacy of Mesenchymal stem cells (MSCs) transplantation after acute myocardial infarction (AMI). However, the results of those studies were ...
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Article
CXXC5 regulates differentiation of C2C12 myoblasts into myocytes
CXXC5 is a member of the CXXC-type zinc-finger domain containing protein family, which is suggested to function in gene transcription, cell adhesion and cytoskeleton organization. Previous studies have reveale...
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Article
Expression and identification of a novel gene Spata34 in mouse spermatogenic cells
Leucine-rich repeat (LRR) containing proteins play an essential role in signal transduction, cell adhesion, cell development, DNA repair and RNA processing. Here we cloned a novel gene, Spata34, encoding a LRR co...
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Article
The effect of excess expression of GFP in a novel heart-specific green fluorescence zebrafish regulated by nppa enhancer at early embryonic development
In order to study the impalpable effect of GFP in homozygous heart-specific GFP-positive zebrafish during the early stage, the researchers analyzed the heart function of morphology and physiology at the first ...
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Article
Evidence for the Formation of the Male Gynogenetic Fish
The females and unexpected males of gynogenetic red crucian carps (GRCC) with the 1:1 sex ratio were found in the progeny of the distant crossing of red crucian carp (RCC; ♀, 2n = 100) × blunt snout bream (BSB; ♂...
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Article
Map** the transcription repressive domain in the highly conserved human gene hnulp1
HNULP1, a new member of the basic helixloop-helix transcription factors, contains a DUF654 domain in its C-terminus and is highly conserved from Drosophilae, yeast, zebrafish to mouse. The function of this motif,...
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Article
The effects of glass surfaces and probe GC content on signal intensities of a 60-mer diagnostic microarray
The effects of glass surfaces and probe GC content on signal intensities of a 60-mer diagnostic microarray were studied. Twelve virus-specific oligonucleotide probes for severe acute respiratory syndrome coron...
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Article
A human homolog of mouse Lbh gene, hLBH, expresses in heart and activates SRE and AP-1 mediated MAPK signaling pathway
It has been reported that mouse Lbh (limb-bud and heart) can regulate cardiac gene expression by modulating the combinatorial activities of key cardiac transcription factors, as well as their individual functi...
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Article
ZNF418, a novel human KRAB/C2H2 zinc finger protein, suppresses MAPK signaling pathway
Cardiac differentiation involves a cascade of coordinated gene expression that regulates cell proliferation and matrix protein formation in a defined temporal-spatial manner. Zinc finger-containing transcripti...
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Article
Advanced studies on human gene ZNF322
The human novel gene of ZNF322 is cloned from human fetal cDNA library using the primers on the basis of the ZNF322 sequence analyzed with computer. The gene is located on Chromosome 6p22.1, and encodes a protein...
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Article
Cloning and expression of a novel human gene, Isl-2, encoded a LIM-homeodomain protein
The LIM-homeodomain (LIM-HD) proteins have a homeodomain and two N-terminal LIM domains, which consist of a conserved cysteine- and histidine-rich structure of two tandem repeated zinc fingers. LIM domain is i...
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Article
A novel zinc-finger protein ZNF436 suppresses transcriptional activities of AP-1 and SRE
Mitogen-activated protein kinases (MAPKs) are evolutionary conserved enzymes in cell signal transduction connecting cell-surface receptors to critical regulatory targets within cells and control cell survival,...
