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590 Result(s)
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Article
Absence of ultrasonic-vibration-induced plasticity in metallic glacial glasses
Metallic glasses (MGs) have been found to exhibit unexpected ultrasonic-vibration-induced plasticity (UVIP), which provides a promising way to realize room temperature processing and molding of MGs. However, w...
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Article
Open AccessDevelopment of machine learning models for patients in the high intrahepatic cholangiocarcinoma incidence age group
Intrahepatic cholangiocarcinoma (ICC) has a poor prognosis and is understudied. Based on the clinical features of patients with ICC, we constructed machine learning models to understand their importance on sur...
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Article
Electroconductive high-entropy metallic oxide ceramic composites with outstanding water evaporation ability and biocompatibility
Electroconductive ceramics were a class of materials that exhibited metal-like conductivity while also retaining the beneficial properties of ceramics. Currently, they were ceramic composites generally fabrica...
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Tunable superconductivity in electron- and hole-doped Bernal bilayer graphene
Graphene-based, high-quality, two-dimensional electronic systems have emerged as a highly tunable platform for studying superconductivity1–21. Specifically, superconductivity has been observed in both electron- a...
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Article
Novel pleiotropic variants associated with type 2 diabetes and polycystic ovary syndrome detected using a pleiotropic cFDR method
Genome-wide association studies (GWASs) on polycystic ovary syndrome (PCOS) and type 2 diabetes (T2D) are usually conducted as single trait, rather than a simultaneous analysis of the related traits. Therefore...
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Open AccessDAB2IP inhibits glucose uptake by modulating HIF-1α ubiquitination under hypoxia in breast cancer
Metabolic reprogramming has become increasingly important in tumor biology research. The glucose metabolic pathway is a major energy source and is often dysregulated in breast cancer. DAB2IP is widely reported...
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Open AccessRetraction Note: Non-thermal plasma inhibits human cervical cancer HeLa cells invasiveness by suppressing the MAPK pathway and decreasing matrix metalloproteinase-9 expression
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Open AccessMechanically robust and personalized silk fibroin-magnesium composite scaffolds with water-responsive shape-memory for irregular bone regeneration
The regeneration of critical-size bone defects, especially those with irregular shapes, remains a clinical challenge. Various biomaterials have been developed to enhance bone regeneration, but the limitations ...
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Article
Effect of food on the pharmacokinetics and safety profiles of a new PARP inhibitor fuzuloparib capsules in healthy volunteers
This study assessed effect of food on pharmacokinetics (PK) and safety of fuzuloparib capsules.
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Open AccessTargeting BMAL1 reverses drug resistance of acute myeloid leukemia cells and promotes ferroptosis through HMGB1-GPX4 signaling pathway
Acute myeloid leukemia (AML) is a refractory hematologic malignancy that poses a serious threat to human health. Exploring alternative therapeutic strategies capable of inducing alternative modes of cell death...
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Article
An improved route to urapidil from 1-(2-methoxyphenyl)piperazine and oxetane
Urapidil is an important drug for the treatment of essential hypertension and intravenously in hypertensive emergencies. Herein, an improved route to Urapidil was introduced. The new designed synthetic route s...
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Article
Open AccessPotassium humate supplementation improves photosynthesis and agronomic and yield traits of foxtail millet
Foxtail millet is a highly nutritious crop, which is widely cultivated in arid and semi-arid areas worldwide. Humic acid (HA), as a common plant growth regulator, is used as an organic fertilizer and feed addi...
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Article
Open AccessCFDepthNet: Monocular Depth Estimation Introducing Coordinate Attention and Texture Features
Handling the depth estimation of low-texture regions using photometric error loss is a challenge due to the difficulty of achieving convergence due to the presence of multiple local minima for pixels in low-te...
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Article
Open AccessCervicovaginal microbiota: a promising direction for prevention and treatment in cervical cancer
Cervical cancer is a common malignancy in women, with high incidence rate and mortality. Persistent infection of high-risk human papillomavirus (HPV) is the most important risk factor for cervical cancer and p...
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Open AccessCorrection: The impact of ageing on the distribution of preformed anti-HLA and anti-MICA antibody specificities in recipients from eastern China prior to initial HSCT
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Article
Efficient Numerical Schemes for a Two-Species Keller-Segel Model and Investigation of Its Blowup Phenomena in 3D
We consider in this paper numerical approximation and simulation of a two-species Keller-Segel model. The model enjoys an energy dissipation law, mass conservation and bound or positivity preserving for the po...
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Open AccessCombination of bone marrow mesenchymal stem cells and moxibustion restores cyclophosphamide-induced premature ovarian insufficiency by improving mitochondrial function and regulating mitophagy
Premature ovarian insufficiency (POI) is a major cause of infertility. In this study, we aimed to investigate the effects of the combination of bone marrow mesenchymal stem cells (BMSCs) and moxibustion (BMSCs...
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Article
Open AccessLight-induced giant enhancement of nonreciprocal transport at KTaO3-based interfaces
Nonlinear transport is a unique functionality of noncentrosymmetric systems, which reflects profound physics, such as spin-orbit interaction, superconductivity and band geometry. However, it remains highly cha...
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Article
Magnetic emission intensity enhancement for amorphous alloys by constructing a multi-phase structure with α-Fe nanocrystals
The perturbation in the magnetic field generated by the rotation or oscillation of magnetic domains in magnetic materials can emit low-frequency electromagnetic waves, which are expected to be used in low-freq...
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Open AccessMagnetic field filtering of the boundary supercurrent in unconventional metal NiTe2-based Josephson junctions
Topological materials with boundary (surface/edge/hinge) states have attracted tremendous research interest. Additionally, unconventional (obstructed atomic) materials have recently drawn lots of attention owi...