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Article
Open AccessRisk factors and machine learning prediction models for bronchopulmonary dysplasia severity in the Chinese population
Bronchopulmonary dysplasia (BPD) is a common chronic lung disease in extremely preterm neonates. The outcome and clinical burden vary dramatically according to severity. Although some prediction tools for BPD ...
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Article
Open AccessLupus susceptibility region containing CTLA4 rs17268364 functionally reduces CTLA4 expression by binding EWSR1 and correlates IFN-α signature
Dysregulation of T cells mediated immune responses is a hallmark in the development of systemic lupus erythematosus (SLE). Recent genome wide association study (GWAS) revealed the genetic contribution of varia...
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Article
Open AccessThe ZNF76 rs10947540 polymorphism associated with systemic lupus erythematosus risk in Chinese populations
Systemic lupus erythematosus (SLE) is a typical autoimmune disease with a strong genetic disposition. Genetic studies have revealed that single-nucleotide polymorphisms (SNPs) in zinc finger protein (ZNF)-codi...
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Article
Open AccessNovel identified associations of RGS1 and RASGRP1 variants in IgA Nephropathy
Known susceptibility loci together can only explain about 6–8% of the disease heritability of IgA nephropathy (IgAN), suggesting that there are still a large number of genetic variants remained to be discovere...
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Article
High-density genoty** of immune-related loci identifies new SLE risk variants in individuals with Asian ancestry
Swapan Nath, Sang-Cheol Bae and colleagues report the results of a large-scale association study of systemic lupus erythematosus in individuals of Asian ancestry. They identify several new susceptibility loci ...
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Article
Open AccessCumulative Effects of Variants Identified by Genome-wide Association Studies in IgA Nephropathy
The effect of genetic markers associated with IgA nephropathy on risk of disease in sub-phenotype and progression is uncertain. Data from 2096 Chinese patients were used to create both un-weighted (uw) and wei...
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Article
Elastic Properties of Monoclinic \(\hbox {ZrO}_{2}\) at Finite Temperatures Via First Principles
The structural and elastic properties of orthorhombic \(\hbox {ZrO}_{2}\,(m\hbox {-ZrO}_{2})\)
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Article
Structural and elastic properties of Ce2O3 under pressure from LDA+U method
We investigate the structural and elastic properties of hexagonal Ce2O3 under pressure using LDA+U scheme in the frame of density functional theory (DFT). The obtained lattice constants and bulk modulus agree wel...
