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Article
Open AccessEvaluation of 10 SLE susceptibility loci in Asian populations, which were initially identified in European populations
Ten novel loci have been found to be associated with systemic lupus erythematosus (SLE) susceptibility by a recent genome-wide association study conducted in Europeans. To test their disease associations and g...
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Article
Open AccessNovel identified associations of RGS1 and RASGRP1 variants in IgA Nephropathy
Known susceptibility loci together can only explain about 6–8% of the disease heritability of IgA nephropathy (IgAN), suggesting that there are still a large number of genetic variants remained to be discovere...
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Article
High-density genoty** of immune-related loci identifies new SLE risk variants in individuals with Asian ancestry
Swapan Nath, Sang-Cheol Bae and colleagues report the results of a large-scale association study of systemic lupus erythematosus in individuals of Asian ancestry. They identify several new susceptibility loci ...
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Article
Open AccessAn HLA-C amino-acid variant in addition to HLA-B*27 confers risk for ankylosing spondylitis in the Korean population
The presence of the HLA-B*27 allele is a major risk factor for the development of ankylosing spondylitis (AS), which causes chronic inflammation of the spine and other sites. We investigated residual effects outs...
