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    Chapter

    Hypoxia: A Formidable Saboteur of the Anti-tumor Response

    The tumor microenvironment (TME) promotes neoplastic transformation, supports tumor growth and invasion, protects the tumor from host immunity and fosters therapeutic resistance. It is well established that tu...

    Meriem Hasmim, Yosra Messai, Stéphane Terry in Resistance of Cancer Cells to CTL-Mediated… (2015)

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    Article

    Crosstalk between CTC, Immune System and Hypoxic Tumor Microenvironment

    Accumulating evidence indicate that the behavior of tumorigenic cells is highly influenced by their microenvironment. In this regard, microenvironmental hypoxia plays a determinant role in the emergence of CTC...

    Muhammad Zaeem Noman, Yosra Messai, Jane Muret, Meriem Hasmim in Cancer Microenvironment (2014)