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Chapter
Hypoxia: A Formidable Saboteur of the Anti-tumor Response
The tumor microenvironment (TME) promotes neoplastic transformation, supports tumor growth and invasion, protects the tumor from host immunity and fosters therapeutic resistance. It is well established that tu...
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Article
Crosstalk between CTC, Immune System and Hypoxic Tumor Microenvironment
Accumulating evidence indicate that the behavior of tumorigenic cells is highly influenced by their microenvironment. In this regard, microenvironmental hypoxia plays a determinant role in the emergence of CTC...