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Article
Identification of novel yolk ferritins unique to planarians: planarians supply aluminum rather than iron to vitellaria in egg capsules
All animals, other than Platyhelminthes, produce eggs containing yolk, referred to as “entolecithal” eggs. However, only Neoophora, in the phylum Platyhelminthes, produce “ectolecithal” eggs (egg capsules), in...
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Article
Open AccessConstruction of transplantable artificial vascular tissue based on adipose tissue-derived mesenchymal stromal cells by a cell coating and cryopreservation technique
Prevascularized artificial three-dimensional (3D) tissues are effective biomaterials for regenerative medicine. We have previously established a scaffold-free 3D artificial vascular tissue from normal human de...
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Article
Inhibitory effect of carbonyl reductase 1 against peritoneal progression of ovarian cancer: evaluation by ex vivo 3D-human peritoneal model
The current authors previously reported that a carbonyl reductase 1 (CR1) DNA-dendrimer complex could potentially be used in gene therapy for peritoneal metastasis of ovarian cancer. The aims of the current st...
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Article
Mice with Disrupted TGFβ Signaling Have Normal Cerebella Development, but Exhibit Facial Dysmorphogenesis and Strain-Dependent Deficits in Their Body Wall
The transforming growth factor betas (TGFβs) are context-dependent regulators of neurons in vitro, but their physiological functions in the brain are unclear. Haploinsufficiency of either Tgfβ1 or Tgfβ2 leads ...
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Article
Visualization of non-heme ferric and ferrous iron by highly sensitive non-heme iron histochemistry in the stress-induced acute gastric lesions in the rat
Redox-active non-heme iron catalyzes hydroxyl radical \({\text{OH}}^{\raise0.145em\hbox{\({\scriptscriptstyle \bullet}\)}} \) ...
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Article
Perfusion-Perls and -Turnbull methods supplemented by DAB intensification for nonheme iron histochemistry: demonstration of the superior sensitivity of the methods in the liver, spleen, and stomach of the rat
Perfusion-Perls and -Turnbull methods supplemented by the intensification with 3,3′-diaminobenzidine (+ DAB) enabled stronger and more extensive staining of nonheme iron than the Perls + and Turnbull + DAB met...
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Article
Monoclonal antibody to stage-specific fetal brain 68-kDa glycoprotein (FGP68) revealed increased FGP68 expression in human primary brain tumors
We have produced a novel rat IgG2a monoclonal antibody against a stage-specific fetal brain glycoprotein of 68 kDa (FGP68), and succeeded in applying it to staining paraffin sections. To gain some insight into t...