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Article
End-of-treatment 18[F]-FDG PET can predict early progression in patients receiving bendamustine-rituximab for follicular lymphoma in first relapse: a prospective West Japan hematology Study Group (W-JHS) NHL01 trial
Response determined by 18[F]-fluoro-2-deoxy-d-glucose (18F-FDG) positron emission tomography (PET)–CT after induction therapy can predict progression-free survival (PFS) in follicular lymphoma (FL). However, litt...
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Article
Open AccessRuxolitinib in steroid-refractory acute graft-vs-host disease: Japanese subgroup analysis of the randomized REACH2 trial
Acute graft-versus-host disease (aGvHD) is a major complication after allogeneic hematopoietic stem cell transplantation in Japan and other countries. Nearly one-third of patients do not respond to standard sy...
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Article
Spontaneous regression of multiple solitary plasmacytoma harboring Epstein–Barr virus: a case report and literature review
We report a rare case of spontaneous regression (SR) in an elderly untreated patient with multiple solitary plasmacytoma (MSP). Diagnosis of MSP was confirmed through surgical resection of the left nasal cavit...
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Article
Open AccessChimeric antigen receptor T-cell therapy after COVID-19 in refractory high-grade B-cell lymphoma
Although chimeric antigen receptor T-cell (CAR-T) therapies have dramatically improved the outcomes of relapsed/refractory B-cell malignancies, recipients suffer from severe humoral immunodeficiencies. Further...
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Article
JSH practical guidelines for hematological malignancies, 2023: I. Leukemia-1. Acute myeloid leukemia (AML)
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Article
Cold agglutinin–induced acrocyanosis without hemolytic anemia
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Article
Characteristic differences in the abundance of tumor-infiltrating lymphocytes and intratumoral develo** T cells in thymoma, with special reference to PD-1 expression
Though programmed cell death-1 (PD-1) inhibitors mainly target tumor-infiltrating lymphocytes (TILs) expressing PD-1, develo** T cells in thymus also express PD-1 in their process of maturation. To predict t...
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Article
More than one-third of advanced non-small-cell lung cancer patients do not receive immunochemotherapy due to intolerance
Combination therapy with immune checkpoint inhibitors (ICIs) and chemotherapy (ICI + chemotherapy) has become the standard first line treatment for driver oncogene-negative advanced non-small-cell lung cancer ...
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Article
Force exerted on maxillary anterior teeth in mandibular unilateral and bilateral distal extension partial edentulous situation
The purpose of this study was to determine the influence of mandibular unilateral and bilateral distal extension partial edentulous situation and the use of removable partial dental prostheses on the force exe...
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Article
Association between early corticosteroid administration and long-term survival in non-infectious pulmonary complications after allogeneic hematopoietic stem cell transplantation
Non-infectious pulmonary complications (NIPCs) after allogeneic hematopoietic stem cell transplantation (HSCT) are associated with poor outcomes. It is important to maximize the effectiveness of primary treatm...
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Article
Open AccessEarly-stage antibody kinetics after the third dose of BNT162b2 mRNA COVID-19 vaccination measured by a point-of-care fingertip whole blood testing
Amid the Coronavirus Disease 2019 pandemic, we aimed to demonstrate the accuracy of the fingertip whole blood sampling test (FWT) in measuring the antibody titer and uncovering its dynamics shortly after boost...
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Article
Open AccessASXL1 mutations with serum EPO levels predict poor response to darbepoetin alfa in lower-risk MDS: W-JHS MDS01 trial
Darbepoetin alfa (DA) is used to treat anemia in lower-risk (IPSS low or int-1) myelodysplastic syndromes (MDS). However, whether mutations can predict the effectiveness of DA has not been examined. The presen...
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Article
Chronic active Epstein–Barr virus infection presenting as refractory chronic sinusitis
A 44-year-old Japanese man presented with fever and sore throat. He had a history of refractory chronic sinusitis that did not respond to several years of pharmacotherapy, and underwent endoscopic sinus surger...
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Article
Pembrolizumab in advanced NSCLC patients with poor performance status and high PD-L1 expression: OLCSG 1801
The role of pembrolizumab in the treatment of poor performance status (PS) patients remains unclear.
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Article
Higher incidence of thrombocytopenia during obinutuzumab plus bendamustine therapy for untreated follicular lymphoma: a retrospective analysis by the Okayama Hematology Study Group
Progression-free survival in patients with untreated follicular lymphoma (FL) has significantly improved with obinutuzumab plus chemotherapy followed by obinutuzumab maintenance, compared with rituximab plus c...
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Article
Possible prognostic impact of WT1 mRNA expression at day + 30 after haploidentical peripheral blood stem cell transplantation with posttransplant cyclophosphamide for patients with myeloid neoplasm: a multicenter study from the Okayama Hematological Study Group
Previous studies have revealed that relapse of myeloid neoplasms after allogeneic hematopoietic stem cell transplantation (allo-HSCT) could be predicted by monitoring Wilms’ tumor 1 (WT1) mRNA expression. Howe...
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Article
A case of redo tricuspid valve repair after neonatal cone operation for Ebstein’s anomaly
Cone reconstruction for Ebstein’s anomaly, although effective, is challenging in neonatal cases. Very few reports have discussed recurrent regurgitation. Herein, we report a successful redo tricuspid valve rep...
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Article
Open AccessIdentification of targetable kinases in idiopathic pulmonary fibrosis
Tyrosine kinase activation plays an important role in the progression of pulmonary fibrosis. In this study, we analyzed the expression of 612 kinase-coding and cancer-related genes using next-generation sequen...
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Chapter
Endometrial Hyperplasia without Atypia
Endometrial hyperplasia without atypia (as in the 2020 WHO classification) is defined as the proliferation of endometrial glands of irregular size and shape without significant cytological atypia. The ratio of...
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Chapter
Endometrial Atypical Hyperplasia/Endometrioid Intraepithelial Neoplasia
Endometrial atypical hyperplasia/endometrioid intraepithelial neoplasia (EAH/EIN) is defined as the simultaneous appearance of cytological atypia in endometrial glands and an increased ratio of endometrial gla...
