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Article
Structural and Functional Analyses of the Flavoprotein Disulfide Reductase FN0820 of Fusobacterium nucleatum
Escherichia coli RclA and Staphylococcus aureus MerA are part of the Group I flavoprotein disulfide reductase (FDR) family and have been implicated in the contribution to bacterial pathogenesis by defending again...
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Article
Open AccessGenomic and metabolomic insights into the antimicrobial compounds and plant growth-promoting potential of Bacillus velezensis Q-426
The Q-426 strain isolated from compost samples has excellent antifungal activities against a variety of plant pathogens. However, the complete genome of Q-426 is still unclear, which limits the potential appli...
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Article
Heterologous expression of quorum sensing transcriptional regulator LitR and its function in virulence-related gene regulation in foodborne pathogen Aeromonas hydrophila
Aeromonas hydrophila is an important foodborne and zoonotic pathogen causing serious diseases. Hence, revealing the pathogenic mechanism of A. hydrophila will be of importance in the development of novel therapie...
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Article
Open AccessTalaromyces marneffei Infections in 8 Chinese Children with Inborn Errors of Immunity
Talaromyces marneffei (TM) is an opportunistic fungus leading to multi-organ damages and poor prognosis in immunocompromised individuals. TM infections in children are rare and our knowledge to TM infection is in...
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Article
Open AccessInnate immune responses against the fungal pathogen Candida auris
Candida auris is a multidrug-resistant human fungal pathogen responsible for nosocomial outbreaks worldwide. Although considerable progress has increased our understanding of the biological and clinical aspects o...
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Article
Open AccessRubus chingii Hu. unripe fruits extract ameliorates carbon tetrachloride-induced liver fibrosis and improves the associated gut microbiota imbalance
The unripe fruits of Rubus chingii Hu. (“Fu-peng-zi” in Chinese) is a well-known herbal tonic in traditional Chinese medicine (TCM) for tonifying liver and kidney. However, little is known regarding its therapeut...
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Article
Open AccessFunctional and structural analysis of catabolite control protein C that responds to citrate
Catabolite control protein C (CcpC) belongs to the LysR-type transcriptional regulator (LTTR) family, which regulates the transcription of genes encoding the tricarboxylic acid branch enzymes of the TCA cycle ...
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Article
Structural Flexibility of Peripheral Loops and Extended C-terminal Domain of Short Length Substrate Binding Protein from Rhodothermus marinus
Substrate binding proteins (SBPs) bind to specific ligands in the periplasmic regions of cells and then bind to membrane proteins to participate in transport or signal transduction. Typically, SBPs consist of ...
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Article
Spectroscopic Analysis of Fe Ion-Induced Fluorescence Quenching of the Green Fluorescent Protein ZsGreen
The fluorescence of fluorescent proteins (FPs) is quenched when they are exposed to certain transition metals, which makes them promising receptor materials for metal biosensors. In this study, we report the s...
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Article
Open AccessActivin a suppresses peripheral CD8+ T lymphocyte activity in acute-phase Kawasaki disease
Kawasaki disease is an autoimmune disease characterized by systemic vasculitis of unknown aetiology and most commonly occurs in children under 5 years old. Previous studies have found that the over-activation ...
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Article
Recent paradigm shift in the assembly of bacterial tripartite efflux pumps and the type I secretion system
Tripartite efflux pumps and the type I secretion system of Gram-negative bacteria are large protein complexes that span the entire cell envelope. These complexes expel antibiotics and other toxic substances or...
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Article
Spectral and structural analysis of large Stokes shift fluorescent protein dKeima570
The Keima family comprises large Stokes shifts fluorescent proteins, which are useful for dual-color fluorescence crosscorrelation spectroscopy and multicolor imaging. dKeima570 belongs to the Keima family. It...
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Article
Comparative study of the physicochemical and photocatalytic properties of water-soluble polymer-capped TiO2 nanoparticles
TiO2 shows great potential as ideal and powerful photocatalyst to degrade and eliminate harmful organic pollutants from waste water. It is desirable to prepare anatase TiO2 with good aqueous solubility and photoc...
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Article
Development of Antimicrobial and Controlled Biodegradable Gelatin-Based Edible Films Containing Nisin and Amino-Functionalized Montmorillonite
The utilization of petroleum-derived synthetic materials causes severe ecological problems, such as environmental pollution and soil degradation. Hence, using naturally derived and renewable materials to fabri...
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Article
Open AccessCrystal structure and functional implications of the tandem-type universal stress protein UspE from Escherichia coli
The universal stress proteins (USP) family member UspE is a tandem-type USP that consists of two Usp domains. The UspE expression levels of the Escherichia coli (E. coli) become elevated in response to oxidative ...
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Chapter and Conference Paper
Research and Implementation of Single Sign-on in Enterprise Systems Application Integration
Single Sign-on (SSO) is an effective unified authentication and authorization mechanism that makes users access to all integrated applications that trust each other from one single-sign-on site. This paper sta...
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Chapter and Conference Paper
Return Forecast of Subscription for New Shares in Growth Enterprise Market Using Simulation Method
This paper studies return of subscribing for new shares in Chinese Growth Enterprise Market (GEM) based on random simulation, and draws some useful conclusions. One is that investors can make more profit by se...
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Article
Periplasmic domain of CusA in an Escherichia coli Cu+/Ag+ transporter has metal binding sites
The resistance nodulation division (RND)-type efflux systems are utilized in Gram-negative bacteria to export a variety of substrates. The CusCFBA system is the Cu+ and Ag+ efflux system in Escherichia coli, conf...
