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Article
Open AccessBiomechanical comparison of the therapeutic effect of a novel proximal femoral bionic intramedullary nail and traditional inverted triangle hollow screw on femoral neck fracture
A novel Proximal Femoral Bionic Nail (PFBN) has been developed by a research team for the treatment of femoral neck fractures. This study aims to compare the biomechanical properties of the innovative PFBN wit...
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Article
Open AccessMolecular ferroelectric with low-magnetic-field magnetoelectricity at room temperature
Magnetoelectric materials, which encompass coupled magnetic and electric polarizabilities within a single phase, hold great promises for magnetic controlled electronic components or electric-field controlled s...
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Article
Supramolecular polymer network constructed by a functionalized polyimidazolium salt derived from metal-carbene template approach
In this study, we present a supramolecular templating approach for constructing polyimidazolium salt containing crown ether and cyclobutane moieties. This strategy involves the formation of metal-carbene templ...
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Article
Open AccessProgesterone receptor potentiates macropinocytosis through CDC42 in pancreatic ductal adenocarcinoma
Endocrine receptors play an essential role in tumor metabolic reprogramming and represent a promising therapeutic avenue in pancreatic ductal adenocarcinoma (PDAC). PDAC is characterized by a nutrient-deprived...
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Article
Open AccessThe efficacy and safety of corticotomy and periodontally accelerated osteogenic orthodontic interventions in tooth movement: an updated meta-analysis
The surgically facilitated orthodontic strategy has been a promising strategy for orthodontic treatment recently. Therefore, the present meta-analysis was conducted to assess the available scientific evidence ...
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Article
Pararhizobium qamdonense sp. nov., Isolated from an Alpine Soil in Tibet and the Reclassification of Rhizobium gei Shi et al. 2016 as Pararhizobium gei comb. nov.
A novel Gram-stain-negative, aerobic, rod-shaped bacterium named T808T was isolated from an alpine soil in Qamdo, Tibet, PR China. Strain T808T grew at 5–30℃, pH 5.0–9.0 (optimum, 25℃ and pH 7.0–8.0) with 0–2% (w...
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Article
Synthesis of magnetic bentonite–gelatin hydrogel beads and their applications in Cu2+ capturing
Heavy metal ions that exist in groundwater and farmland jeopardize the ecological environment and are very difficult to remove because of the complicated actual environment. Raw bentonite–gelatin beads (RB-GT)...
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Article
Open AccessThe oral bacterial microbiota facilitates the stratification for ulcerative colitis patients with oral ulcers
Clinically, a large part of inflammatory bowel disease (IBD) patients is complicated by oral lesions. Although previous studies proved oral microbial dysbiosis in IBD patients, the bacterial community in the g...
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Article
Open AccessPredicting survival of advanced laryngeal squamous cell carcinoma: comparison of machine learning models and Cox regression models
Laryngeal squamous cell carcinoma (LSCC) is a common tumor type. High recurrence rates remain an important factor affecting the survival and quality of life of advanced LSCC patients. We aimed to build a new n...
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Article
Targeted VEGFA therapy in regulating early acute kidney injury and late fibrosis
Damage to peritubular capillaries is a key process that contributes to acute kidney injury (AKI) progression. Vascular endothelial growth factor A (VEGFA) plays a critical role in maintaining the renal microva...
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Article
Insight-HXMT on-orbit thermal control status and thermal deformation impact analysis
The Hard X-ray Modulation Telescope is China’s first X-ray astronomy satellite launched on June 15, 2017, dubbed Insight-HXMT. Active and passive thermal control measures are employed to keep devices at suitable ...
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Open AccessCorrection to: Lycium barbarum glycopeptide targets PER2 to inhibit lipogenesis in glioblastoma by downregulating SREBP1c
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Article
Salvianolic Acid B Attenuates Hypertrophic Scar Formation In Vivo and In Vitro
Hypertrophic scars (HTSs) are a fibroproliferative disorder that occur following skin injuries. Salvianolic acid B (Sal-B) is an extractant from Salvia miltiorrhiza that has been reported to ameliorate fibrosis i...
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Article
Open AccessLycium barbarum glycopeptide targets PER2 to inhibit lipogenesis in glioblastoma by downregulating SREBP1c
Lycium barbarum polysaccharide (LBP) is a substance with various biological activities extracted from Lycium barbarum. LbGPs are peptidoglycans with a short peptide backbone and a complex, branched glycan moiety,...
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Article
EZH2 Contributes to Anoikis Resistance and Promotes Epithelial Ovarian Cancer Peritoneal Metastasis by Regulating m6A
Histone modification has a significant effect on gene expression. Enhancer of zeste homolog 2 (EZH2) contributes to the epigenetic silencing of target chromatin through its roles as a histone-lysine N-methyltr...
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Article
A quick online cross-sectional study of knowledge, attitude, practice, and information media toward the Omicron pandemic in China
The knowledge, attitudes, and practices (KAP) toward the COVID-19 and popular information media of the public is unclear in the late pandemic. The objective of this study was to evaluate the Chinese residents’...
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Article
Open AccessSEPT2 crotonylation promotes metastasis and recurrence in hepatocellular carcinoma and is associated with poor survival
Hepatocellular carcinoma (HCC) metastasis and recurrence lead to therapy failure, which are closely associated with the proteome. However, the role of post-translational modification (PTM) in HCC, especially f...
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Article
The extension characteristics and mixing effect of the secondary impact surface in double-layer im**ing stream mixer
The two-dimensional particle image velocimetry (TR-PIV) technology was used to measure the velocity field in a double-layer im**ing stream mixer. The variation of secondary impact surface extension amount in...
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Article
Distribution patterns of landslides triggered by the 2022 Ms 6.8 Luding earthquake, Sichuan, China
At 12:52 pm on September 5, 2022, an Ms 6.8 earthquake occurred in Luding County, Sichuan Province, China. Based on high-resolution aerial photographs and satellite imageries obtained after the earthquake, as ...
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Article
PpyMYB144 transcriptionally regulates pear fruit skin russeting by activating the cytochrome P450 gene PpyCYP86B1
PpyMYB144 directly activates the promoter of PpyCYP86B1, promotes the synthesis of α, ω-diacids, and involves in pear fruit skin russeting.
