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Article
Open AccessProinflammatory polarization of engineered heat-inducible macrophages reprogram the tumor immune microenvironment during cancer immunotherapy
The success of macrophage-based adoptive cell therapy is largely constrained by poor polarization from alternatively activated (M2-like) to classically activated (M1-like) phenotype in the immunosuppressive tu...
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Article
Open AccessCirculating exosomal mir-16-2-3p is associated with coronary microvascular dysfunction in diabetes through regulating the fatty acid degradation of endothelial cells
Coronary microvascular dysfunction (CMD) is a frequent complication of diabetes mellitus (DM) characterized by challenges in both diagnosis and intervention. Circulating levels of microRNAs are increasingly re...
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Article
Non-invasive activation of intratumoural gene editing for improved adoptive T-cell therapy in solid tumours
Adoptive T-cell therapy against solid tumours is limited by the apoptosis resistance mechanisms of tumour cells and by the extracellular, immunosuppressive tumour microenvironment. Here we report a temperature...
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Article
Open AccessBiochar-derived dissolved organic matters influencing bacterium characteristics during biodegradation of sulfamethoxazole and chloramphenicol under alternation of visible and avoiding light
The influence of biochar-released dissolved organic matter (BDOM) on the transcription of gene (DEG) in Pseudomonas stutzeri and Shewanella putrefacien during sulfamethoxazole (SMX) and chloramphenicol (CAP) biod...
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Chapter and Conference Paper
Accelerating Urban Green Economic Growth Through Government Guidance Funds: Case Study of a National Green Finance Pilot City
The profound and lasting influence of Covid-19 and the global consensus of carbon peaking and carbon neutrality is reforming the underlying logic of economic development, and the green economy will become a ne...
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Article
Exosome-Encapsulated microRNA-140-5p Alleviates Neuronal Injury Following Subarachnoid Hemorrhage by Regulating IGFBP5-Mediated PI3K/AKT Signaling Pathway
Recent literature has highlighted the therapeutic implication of exosomes (Exos) released by adipose tissue-originated stromal cells (ADSCs) in regenerative medicine. Herein, the current study sought to examin...
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Article
Synthesis of AirRGO@FeCo hollow microspheres with strong microwave absorption properties
A kind of reduced graphene oxide hollow microspheres loaded with FeCo alloy (AirRGO@FeCo) was synthesized by oil-in-water emulsification technology and high-temperature calcination process. By controlling the ...
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Article
Photosynthetic biomaterials: applications of photosynthesis in algae as oxygenerator in biomedical therapies
For most organisms, molecular oxygen is indispensable for normal physiological metabolism; in humans, prolonged hypoxia in tissues can induce many diseases, exemplified by cardiovascular disease, chronic wound...
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Article
Porous SBA-15/cellulose membrane with prolonged anti-microbial drug release characteristics for potential wound dressing application
A sustained release of anti-infection drugs is beneficial for the reduction of required dressing change times and the protection of the granulation tissue against further infection. In this work, the strategy ...
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Article
Small cell carcinoma of the bladder: the characteristics of molecular alterations, treatment, and follow-up
Small cell carcinoma of the bladder (SCCB) is a rare disease associated with high invasiveness and mortality. Histologically, SCCB is difficult to distinguish from small cell lung cancer (SCLC); however, it sh...
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Article
Biocompatible and photoluminescent carbon dots/hydroxyapatite/PVA dual-network composite hydrogel scaffold and their properties
Fluorescence imaging in vivo can non-invasively monitor and reveal the process of the implants. In this work, it has developed a novel Carbon dots/Hydroxyapatite/PVA (CDs/HA/PVA) dual-network (DN) hydrogel sca...
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Article
An analytical poroelastic model for laboratorial mechanical testing of the articular cartilage (AC)
The articular cartilage (AC) can be seen as a biphasic poroelastic material. The cartilage deformation under compression mainly leads to an interstitial fluid flow in the porous solid phase. In this paper, an ...
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Article
A facile and green strategy for the preparation of porous chitosan-coated cellulose composite membranes for potential applications as wound dressing
A combination of a superior hygroscopic capacity, mechanical strength and antibacterial activity is required for a wound dressing material. To this end, a facile and green technique to prepare porous composite...
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Article
A strategy for improving mechanical properties of composite nanofibers through surface functionalization of fillers with hyperbranched polyglycerol
This study aims to develop a strategy to promote the mechanical properties of nanofiller/polymer composite nanofibers, i.e., nanofillers was modified with hyperbranched polyglycerol (PG) by ring-opening polyme...
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Article
Intracellular localization of rice stripe virus RNA-dependent RNA polymerase and its interaction with nucleocapsid protein
The RNA-dependent RNA polymerase (RdRp) of rice stripe virus (RSV) is critical for both the transcription and replication of the viral genome. Despite its importance, little is known about how it functions in ...
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Article
The RNA-binding properties and domain of Rice stripe virus nucleocapsid protein
The nucleocapsid protein (NP) of rice stripe virus (RSV) encapsidates viral genomic RNAs to form virion. The binding of NP with RNA is essential for the formation of virus particle. In this study, the binding ...
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Article
Tailor-made magnetic nanocarriers with pH-induced charge reversal and pH-responsiveness to guide subcellular release of doxorubicin
A charge reversible, magnetic-targeted, and pH-responsive nano therapy system assembled from citraconic-modified dextran (Dex–COOH), glycine-stabilized superparamagnetic iron oxide nanoparticles (SPION–NH2), and ...
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Article
Toughening of electrospun poly(l-lactic acid) nanofiber scaffolds with unidirectionally aligned halloysite nanotubes
The mechanical properties of the tissue engineering scaffold are important as they are tightly related the regeneration of structural tissue. The application of poly(l-lactic acid) (PLLA) nanofiber scaffolds in t...
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Article
The Ac124 protein is not essential for the propagation of Autographa californica multiple nucleopolyhedrovirus, but it is a viral pathogenicity factor
orf124 (ac124) of AcMNPV is one of the highly conserved unique genes in group I lepidopteran nucleopolyhedroviruses. So far, its function remains unknown. In this study, infection with a virus ex...
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Article
Preparation and properties of nanodiamond/poly(lactic acid) composite nanofiber scaffolds
Nanodiamonds (NDs) were employed for the first time to enhance the mechanical properties of poly(lactic acid) (PLA)-based nanofiber scaffolds. Uniform ND/PLA composite nanofibers can be electrospun at <1 wt% l...
