86 Result(s)
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Chapter and Conference Paper
Analysis of Cell Death by Flow Cytometry
Apoptosis and necrosis denote two distinct modes of cell death. The distinction is based on differences in morphological, biochemical and molecular changes that occur within the dying cell (revie...
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Article
Purification, characterization and gene sequence analysis of a novel cytochrome c co-induced with reductive dechlorination activity in Desulfomonile tiedjei DCB-1
The sulfate-reducing bacterium, Desulfomonile tiedjei DCB-1, conserves energy for growth from reductive dechlorination of 3-chlorobenzoate via halorespiration. To understand this respiratory process better, we ex...
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Article
RNAi and microRNA: breakthrough technologies for the improvement of plant nutritional value and metabolic engineering
This article raises the complex issue of improving plant nutritional value through metabolic engineering and the potential of using RNAi and micro RNA technologies to overcome this complexity, focusing on a fe...
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Article
Metabolic profiling by ion mobility mass spectrometry (IMMS)
Ion Mobility Mass Spectrometry (IMMS) was evaluated as an analytical method for metabolic profiling. The specific instrument used in these studies was a direct infusion (DI)-electrospray ionization (ESI)—ambie...
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Article
Gene frequency of five genetic characteristics in six nationalities in Southern Guizhou Province, China
Five characteristics (hair forms, nasal profile, nostril forms, mongoloid fold and upper eyelid fold) were respectively investigated in six nationalities, including the Buyi, Miao, Shui, Maonan, Dong, and Han ...
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Article
Open AccessBinding of PFOS to serum albumin and DNA: insight into the molecular toxicity of perfluorochemicals
Health risk from exposure of perfluorochemicals (PFCs) to wildlife and human has been a subject of great interest for understanding their molecular mechanism of toxicity. Although much work has been done, the ...
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Article
Necrostatin-1 reverts shikonin-induced necroptosis to apoptosis
Degterev et al. previously demonstrated that death receptor mediated apoptosis could be diverted to necroptosis when apoptosis signaling was blocked, suggesting that necroptosis may function as a backup mechan...
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Article
LIM domain only 4 protein promotes granulocyte colony-stimulating factor-induced signaling in neurons
Granulocyte colony-stimulating factor (GCSF) is currently in clinical trials to treat neurodegenerative diseases and stroke. Here, we tested whether LIM domain only 4 protein (LMO4), a hypoxia-inducible gene t...
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Article
Telomerase activity-independent function of TERT allows glioma cells to attain cancer stem cell characteristics by inducing EGFR expression
Telomerase reverse transcriptase (TERT), the catalytic subunit of the enzyme telomerase, is robustly expressed in cancer cells. TERT enables cells to avoid chromosome shortening during repeated replication by ...
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Article
Labeling and tracking human amniotic epithelial cells with green fluorescent protein in an adeno-associated virus vector
Human amniotic epithelial cells (hAECs) are a recently identified type of stem cell. Thanks to their ready availability and the lower risk of teratoma formation, hAECs have been studied and tested for a variet...
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Article
A mutational study of Cnu reveals attractive forces between Cnu and H-NS
Cnu is a small 71-amino acid protein that complexes with H-NS and binds to a specific sequence in the replication origin of the E. coli chromosome. To understand the mechanism of interaction between Cnu and H-NS,...
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Article
Open AccessAblation of LMO4 in glutamatergic neurons impairs leptin control of fat metabolism
The LIM domain only 4 (LMO4) protein is expressed in the hypothalamus, but its function there is not known. Using mice with LMO4 ablated in postnatal glutamatergic neurons, including most neurons of the parave...
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Article
A novel accessory molecule Trim59 involved in cytotoxicity of BCG-activated macrophages
BCG-activated macrophages (BAM) could kill the tumor cells through cell-cell contact. In this process membrane proteins play an important role. However, up to date, few membrane proteins were revealed. In this...
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Article
Pseudomonas nitritireducens sp. nov., a nitrite reduction bacterium isolated from wheat soil
A Gram-negative, non-mobile, polar single flagellum, rod-shaped bacterium WZBFD3-5A2T was isolated from a wheat soil subjected to herbicides for several years. Cells of strain WZBFD3-5A2T grow optimally on Luria-...
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Article
Open AccessTubby is required for trafficking G protein-coupled receptors to neuronal cilia
Tubby is the founding member of the tubby-like family of proteins. The naturally occurring tubby mutation in mice causes retinitis pigmentosa, hearing loss and obesity. Tubby has been proposed to function as an a...
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Article
Effect of Arborvitae Seed on Cognitive Function and α7nAChR Protein Expression of Hippocampus in Model Rats with Alzheimer’s Disease
The aim was to investigate the effect of the arborvitae seed on cognitive function and α7-nicotinic acetylcholine receptor (α7nAChR) protein expression of the hippocampus in model rats with Alzheimer’s disease...
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Article
Efficacy of Various Combined Blood Purification Techniques for Treating Patients with Non-viral Acute Liver Failure
We sought to study the clinical efficacy of various combined blood purification techniques in patients with non-viral acute liver failure complicated by multiple organ dysfunction syndrome (MODS). For this pur...
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Article
Combination of Periaortic Elastase Incubation and Cholesterol-Rich Diet: A Novel Model of Atherosclerosis in Rabbit Abdominal Aorta
Atherosclerosis, the leading cause of most cardiovascular disease, is a progressive multifaceted inflammatory disease characterized by extracellular matrix degradation and extensive remodeling of artery wall. ...
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Article
Hemodiafiltration Combined with Resin-Mediated Absorption as a Therapy for Hyperlipidemic Acute Pancreatitis
The aim of this study is to investigate whether hemodiafiltration combined with resin-mediated absorption is a better therapy for hyperlipidemic acute pancreatitis. Patients (n = 67) with acute pancreatitis treat...
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Article
Late Remote Ischemic Preconditioning Provides Benefit to Patients Undergoing Elective Percutaneous Coronary Intervention
To assess whether late remote ischemic preconditioning (L-RIPC) is effective in myocardial protection in patients with ischemic heart disease undergoing elective percutaneous coronary intervention (PCI). L-RIP...
