-
Article
A New Unsaturated Fatty Acid from Marine-Derived Fungus Aspergillus sp. SCAU150
A new pantheric acid G (1), together with two known heterospirocyclic β-lactam derivatives (2 and 3), were isolated from a culture broth of the marine-derived fungus Aspergillus sp. SCAU150. Their structures were...
-
Article
Study on Bioactive Secondary Metabolites from the Mangrove-Derived Fungus Penicillium verruculosum TGM14
A new compound, named penicillquei C (1), and eight known compounds (2–9), were isolated from the fermentation broth of mangrove-derived fungus Penicillium verruculosum TGM14. The structure of compound 1 was iden...
-
Article
A New Polyketide from the Mangrove-Derived Fungus Phomopsis sp. TJM1-5
A new polyketide, 9(E)-3-(5,8-dihydroxynon-3-en-1-yl)-5,6-dihydroxy-2,6-dimethylcyclohex-2-enone (1), and one known compound, 5-chloroisorotiorin (2), were isolated from the mangrove-derived fungus Phomopsis sp. ...
-
Article
Hygrocin C from marine-derived Streptomyces sp. SCSGAA 0027 inhibits biofilm formation in Bacillus amyloliquefaciens SCSGAB0082 isolated from South China Sea gorgonian
Several ansamycins have been reported to inhibit bacterial biofilm formation and accelerate the eradication of developed biofilms, but little is known about the effect of hygrocin C, an ansamycin, on bacterial...
-
Article
Pteridic acids C–G spirocyclic polyketides from the marine-derived Streptomyces sp. SCSGAA 0027
Five new pteridic acids C–G (1–5) were isolated from a culture broth of the marine-derived actinomycete Streptomyces sp. SCSGAA 0027. Their complete structures were elucidated on the basis of NMR data, modified M...
-
Article
Penicillenols from a deep-sea fungus Aspergillus restrictus inhibit Candida albicans biofilm formation and hyphal growth
Penicillenols (A1, A2, B1, B2, C1 and C2) were isolated from Aspergillus restrictus DFFSCS006, and could differentially inhibit biofilm formation and eradicate pre-developed biofilms of Candida albicans. Their st...
-
Article
Antifouling potentials of eight deep-sea-derived fungi from the South China Sea
Marine-derived microbial secondary metabolites are promising potential sources of nontoxic antifouling agents. The search for environmentally friendly and low-toxic antifouling components guided us to investig...
-
Article
Enhanced production of a novel cytotoxic chromone oxalicumone A by marine-derived mutant Penicillium oxalicum SCSIO 24–2
Many marine natural products hold great potential for the development of new and much needed drugs. However, the production of active metabolites by marine-derived microorganisms is usually very low, and large...