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  1. Article

    Open Access

    Impact of Online Video Game-Based Dichoptic Training on Binocular Vision Rehabilitation in Post-surgical Patients with Intermittent Exotropia

    Dichoptic training has emerged as a promising rehabilitation approach for improving binocular visual function in patients with strabismus. A prospective observational study design was employed to assess the ef...

    Xuan Qiu, Yusong Zhou, ** Yu, Zhonghao Wang, Tao Shen in Ophthalmology and Therapy (2024)

  2. Article

    Open Access

    Retina Fundus Photograph-Based Artificial Intelligence Algorithms in Medicine: A Systematic Review

    We conducted a systematic review of research in artificial intelligence (AI) for retinal fundus photographic images. We highlighted the use of various AI algorithms, including deep learning (DL) models, for ap...

    Andrzej Grzybowski, Kai **, **gxin Zhou, **angji Pan in Ophthalmology and Therapy (2024)

  3. Article

    Open Access

    Analytical Characterization for Similarity Assessment Between an Aflibercept Biosimilar SB15 and Reference Product (Eylea®)

    SB15 is a proposed biosimilar product of reference aflibercept (Eylea®), an approved biological drug product for retinal diseases including neovascular age-related macular degeneration (nAMD). This study aimed to...

    Hangyeore Lee, Jongcheol Huh, Dayoung Kim, Soye Lee, Jaeil Lee in Ophthalmology and Therapy (2024)

  4. Article

    Open Access

    Pre-Clinical Studies of a Novel Bispecific Fusion Protein Targeting C3b and VEGF in Neovascular and Nonexudative AMD Models

    KNP-301 is a bi-specific fragment crystallizable region (Fc) fusion protein, which inhibits both C3b and vascular endothelial growth factor (VEGF) simultaneously for patients with late-stage age-related macula...

    Yeri Lee, Donggeon Kim, Philip E. D. Chung, Minkyeong Lee in Ophthalmology and Therapy (2024)

  5. Article

    Open Access

    Investigating the Influence of Temperature and Supplementation Timing on Antifungal Efficacy in Storage Medium for Corneal Transplantation

    Although antifungal supplementation reduces the fungal load in the corneal storage medium, consensus is lacking on the influence of dosing and temperature. The study aims to evaluate the impact of eye bank war...

    Hsin-Yu Liu, Pao-Yu Chen, Hsiao-Sang Chu, Ya-Ting Chiu in Ophthalmology and Therapy (2024)

  6. No Access

    Article

    Association between body mass index and semen quality: a systematic review and meta-analysis

    The continuous decline of human semen quality during the past decades has drawn much concern globally. Previous studies have suggested a link between abnormal BMI and semen quality decline, but the results rem...

    Yingxin Li, Yi Lin, Changkui Ou, Ruijun Xu in International Journal of Obesity (2024)

  7. Article

    Open Access

    LncRNA PITPNA-AS1 mediates the diagnostic potential of miR-129-5p in prostate cancer

    LncRNA has an effective value in many diseases, which has long been applied in the diagnosis, treatment and prognosis of prostate cancer. This study focused on lncRNA PITPNA-AS1, and its diagnostic potential i...

    Zhaolu Song, Silei Xu, **aohui Gu, Qiang Feng, Chang Wang in BMC Urology (2024)

  8. Article

    Open Access

    Efficacy and safety of glucocorticoids in the treatment of COVID-19: a systematic review and meta-analysis of RCTs

    In the realm of acute respiratory infections, coronavirus disease-19 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), poses a global public health challenge. The application ...

    **angrong Ye, Ye Li, Feng Luo, Zhibin Xu in Clinical and Experimental Medicine (2024)

  9. Article

    Open Access

    Impact and effect of imaging referral guidelines on patients and radiology services: a systematic review

    The objective of this systematic review was to offer a comprehensive overview and explore the associated outcomes from imaging referral guidelines on various key stakeholders, such as patients and radiologists.

    Yi **ang Tay, Shane Foley, Ronan Killeen, Marcus E. H. Ong in European Radiology (2024)

  10. Article

    Open Access

    Differences of clinical phenotype between familial and sporadic Crohn’s disease in East China

    Family history is one of the strongest risk factors for inflammatory bowel diseases (IBD) while studies about the clinical phenotype of familial IBD are limited. This study aimed to compare the phenotypic feat...

    Siyuan Dong, **aoxia **ang, Yu Zhang in International Journal of Colorectal Disease (2024)

  11. No Access

    Article

    Development and validation of nomogram for predicting the risk of transferring to the ICU for children with influenza

    Development of a nomogram model for predicting the magnitude of risk of transferring hospitalized children with influenza to the ICU.

    Ruiyang Sun, Xue Zhang, Jiapu Hou, Wanyu Jia in European Journal of Clinical Microbiology … (2024)

  12. No Access

    Article

    Ultra-processed food consumption and risk of diabetes: results from a population-based prospective cohort

    Understanding the impact of the overall construct of ultra-processed foods on diabetes risk can inform dietary approaches to diabetes prevention. In this study, we aimed to evaluate the association between ult...

    Shutong Du, Valerie K. Sullivan, Michael Fang, Lawrence J. Appel in Diabetologia (2024)

  13. Article

    Open Access

    Diffusion-tensor magnetic resonance imaging as a non-invasive assessment of extracellular matrix remodeling in lumbar paravertebral muscles of rats with sarcopenia

    Extracellular matrix (ECM) remodeling in skeletal muscle is a significant factor in the development of sarcopenia. This study aims to evaluate changes in ECM remodeling in the lumbar paravertebral muscles of s...

    **n-Chen Huang, Ji-Yao Ma, Chao Gao, Jia-**n Chen in BMC Musculoskeletal Disorders (2024)

  14. Article

    Open Access

    Analysis of factors related to recanalization of portal vein thrombosis in liver cirrhosis: a retrospective cohort study

    Portal vein thrombosis (PVT) is a common complication of liver cirrhosis, yet there are fewer studies about predictors of PVT recanalization. We aimed to further explore the predictors of recanalization in cir...

    Yali Shi, Wanlin Feng, Jiaman Cai, Zhonglin Wang, Ying Pu in BMC Gastroenterology (2024)

  15. Article

    Open Access

    Targeting CD73 limits tumor progression and enhances anti-tumor activity of anti-PD-1 therapy in intrahepatic cholangiocarcinoma

    Patients with intrahepatic cholangiocarcinoma (iCCA) respond poorly to immune checkpoint blockades (ICBs). In this study, we aimed to dissect the potential mechanisms underlying poor response to ICBs and explo...

    Bao-Ye Sun, Dai Zhang, Wei Gan, **g-Fang Wu in Journal of Cancer Research and Clinical On… (2024)

  16. Article

    Open Access

    Exosomes derived from human urine–derived stem cells ameliorate IL-1β-induced intervertebral disk degeneration

    Human intervertebral disk degeneration (IVDD) is a sophisticated degenerative pathological process. A key cause of IVDD progression is nucleus pulposus cell (NPC) degeneration, which contributes to excessive e...

    Guang Qian, Yueming Yu, Youhai Dong, Yang Hong in BMC Musculoskeletal Disorders (2024)

  17. Article

    Open Access

    Trace of delirium after robotic lower abdominal tumor resection at different end-tidal carbon dioxide: a RCT trial

    Postoperative delirium (POD) often occurs in oncology patients, further increasing the medical and financial burden. Robotic technology in lower abdominal tumors resection reduces surgical trauma but increases...

    **gwen Chen, Si Liang, Ming Wei, Yue Ma, Tianpeng Bi, Zheng Liu in BMC Anesthesiology (2024)

  18. No Access

    Article

    Ultra-high b-value DWI in rectal cancer: image quality assessment and regional lymph node prediction based on radiomics

    This study aims to evaluate image quality and regional lymph node metastasis (LNM) in patients with rectal cancer (RC) on multi-b-value diffusion-weighted imaging (DWI).

    Yongfei Hao, Jianyong Zheng, Wanqing Li, Wanting Zhao, Jianmin Zheng in European Radiology (2024)

  19. Article

    Open Access

    An analysis of the role of GAB2 in pan-cancer from a multidimensional perspective

    To explore the role of GAB2 in pan-cancer based on bioinformatics analysis.

    Yi Yin, Yong Li, Yaoyang Zhang, Qiucheng Jia, Huiming Tang in Discover Oncology (2024)

  20. Article

    Open Access

    Association between neural prosody discrimination and language abilities in toddlers: a functional near-infrared spectroscopy study

    Language delay affects near- and long-term social communication and learning in toddlers, and, an increasing number of experts pay attention to it. The development of prosody discrimination is one of the earli...

    YanRu Guo, YanWei Li, FuLin Liu, Huan** Lin, YuYing Sun, JiaLin Zhang in BMC Pediatrics (2024)

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