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Article
Synthesis and Properties of “Reduced Graphene Oxide –Copper” Composites Produced by the Method of Repeated Pressing and Sintering
We study composites with copper matrix reinforced by plates of graphene oxide produced by the method of repeated pressing and sintering. We determine the hardness, relative density, ultimate strength, elongati...
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Article
A dominant population of optically invisible massive galaxies in the early Universe
Our current knowledge of cosmic star-formation history during the first two billion years (corresponding to redshift z > 3) is mainly based on galaxies identified in rest-frame ultraviolet light1. However, this p...
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Article
New Co(II) And Mn(II) Complexes with 4′-Substituted 2,2′:6′,2″-Terpyridine Ligands
Three Co(II) complexes [Co(meophtpy)2](ClO4)2·2CH3CN (1), [Co(nh2phtpy)2](ClO4)2·2CH3CN (2), [Co(ftpy)2](ClO4)2·2CH3CN (3) and three Mn(II) complexes [Mn(nme2phtpy)2]·(ClO4)2·2CH3CN (4), [Mn(ftpy)2](ClO4)2·CH3CN ...
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Article
Open AccessMicroRNA profiling in clear cell renal cell carcinoma tissues potentially links tumorigenesis and recurrence with obesity
Twenty to 40% localised RCC patients may experience recurrence after curative surgery. Limited miRNA predictors have been identified for ccRCC recurrence.
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Article
Photoreceptor rescue by an abbreviated human RPGR gene in a murine model of X-linked retinitis pigmentosa
The X-linked RP3 gene codes for the ciliary protein RPGR and accounts for over 10% of inherited retinal degenerations. The critical RPGR-ORF15 splice variant contains a highly repetitive purine-rich linker region...
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Article
Open AccessSevere obesity prior to diagnosis limits survival in colorectal cancer patients evaluated at a large cancer centre
In contrast to the consistent evidence for obesity and colorectal cancer (CRC) risk, the impact of obesity in CRC patients is less clear. In a well-characterised cohort of CRC patients, we prospectively evalua...
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Article
Wnt signaling pathway pharmacogenetics in non-small cell lung cancer
Wingless-type protein (Wnt)/β-catenin pathway alterations in non-small cell lung cancer (NSCLC) are associated with poor prognosis and resistance. In 598 stage III–IV NSCLC patients receiving platinum-based ch...
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Article
The laminar–turbulent transition in a fibre laser
Studying the transition from a linearly stable coherent laminar state to a highly disordered state of turbulence is conceptually and technically challenging, and of great interest because all pipe and channel ...
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Article
Open AccessThe human cadherin 11 is a pro-apoptotic tumor suppressor modulating cell stemness through Wnt/β-catenin signaling and silenced in common carcinomas
Genetic alterations of 16q21-q22, the locus of a 6-cadherin cluster, are frequently involved in multiple tumors, suggesting the presence of critical tumor suppressor genes (TSGs). Using 1 Mb array comparative ...
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Open AccessP04.19. T’ai chi as exercise among middle age and elderly Chinese in urban China
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Article
Open AccessAssociation of genetic variation in FTO with risk of obesity and type 2 diabetes with data from 96,551 East and South Asians
FTO harbours the strongest known obesity-susceptibility locus in Europeans. While there is growing evidence for a role for FTO in obesity risk in Asians, its association with type 2 diabetes, i...
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Article
Open AccessCancer risk in patients hospitalised for Graves’ disease: a population-based cohort study in Sweden
The possibility of an association of Graves’ disease (GD) with subsequent cancers raised by certain studies.
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Article
Open AccessCancer risk in hospitalised psoriasis patients: a follow-up study in Sweden
We examined overall and specific cancer risks among Swedish subjects who had been hospitalised one or more times for psoriasis. A database was created by identifying such patients from the Swedish Hospital Dis...
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Article
Open AccessCancer risk in hospitalised asthma patients
Asthma is an increasingly common disorder, affecting 5–10% of the population. It involves a dysregulated immune function, which may predispose to subsequent cancer. We examined cancer risk among Swedish subjec...
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Article
Influence of UGT1A9 intronic I399C>T polymorphism on SN-38 glucuronidation in Asian cancer patients
Genetic polymorphisms in hepatically expressed UGT1A1 and UGT1A9 contribute to the interindividual variability i-n irinotecan disposition and toxicity. We screened UGT1A1 (UGT1A1*60, g.−3140G>A, UGT1A1*28 and UGT...
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Article
An accurate stress analysis model for angle-ply laminates with weakly bonded layers
This paper presents a shear slip model suitable for the analysis of angle-ply composite laminated plates with weakly bonded layers. Being an extension of a relevant model that deals with perfectly bonded lamin...