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  1. Article

    Open Access

    Twins with different personalities: STAT5B—but not STAT5A—has a key role in BCR/ABL-induced leukemia

    Deregulation of the Janus kinase/signal transducers and activators of transcription (JAK/STAT) signaling pathway is found in cancer with STAT5A/B controlling leukemic cell survival and disease progression. As ...

    Sebastian Kollmann, Eva Grundschober, Barbara Maurer, Wolfgang Warsch in Leukemia (2019)

  2. No Access

    Article

    BCR-ABL uncouples canonical JAK2-STAT5 signaling in chronic myeloid leukemia

    Although JAK2 inhibitors were proposed to be beneficial in chronic myeloid leukemia, myeloid transformation and STAT5 activation in BCR-ABL–positive leukemias are JAK2 independent. Mechanistic investigations r...

    Oliver Hantschel, Wolfgang Warsch, Eva Eckelhart, Ines Kaupe in Nature Chemical Biology (2012)

  3. Article

    Open Access

    Screening for serine/threonine kinases phosphorylating Stat5

    Angelika Berger, Andrea Hölbl, Wolfgang Warsch, Veronika Sexl in BMC Pharmacology (2011)

  4. Article

    Open Access

    The transcription factor STAT5 drives mutation and imatinib resistance in chronic myeloid leukemia via ROS production

    Eva Grundschober, Wolfgang Warsch, Veronika Sexl in BMC Pharmacology (2011)