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  1. Article

    Open Access

    The efficacy and safety of short-course radiotherapy followed by sequential chemotherapy and Cadonilimab for locally advanced rectal cancer: a protocol of a phase II study

    For patients with locally advanced rectal cancer (LARC), total neoadjuvant therapy (TNT), namely, intensifying preoperative treatment through the integration of radiotherapy and systemic chemotherapy before su...

    Tongzhen Xu, Lingling Feng, Wenjue Zhang, Haoyue Li, Huiying Ma in BMC Cancer (2024)

  2. Article

    Open Access

    Construction of an immune-related risk score signature for gastric cancer based on multi-omics data

    Early identification of gastric cancer (GC) is associated with a superior survival rate compared to advanced GC. However, the poor specificity and sensitivity of traditional biomarkers suggest the importance o...

    Ying Wang, Wenting Huang, Shanshan Zheng, Liming Wang, Lili Zhang in Scientific Reports (2024)

  3. Article

    Open Access

    A case of Gitelman syndrome with homozygous SLC12A3 deletion presenting with epilepsy

    Gitelman syndrome (GS) is a rare autosomal recessive hereditary renal tubular disorder characterized by hypokalemia, metabolic alkalosis, hypomagnesemia, and hypocalciuria.

    Ying Wang, Wenting Huang, Jia Li, Shumin Mao, Wenqiang Fang in Acta Epileptologica (2023)

  4. Article

    Open Access

    CrMP-Sol database: classification, bioinformatic analyses and comparison of cancer-related membrane proteins and their water-soluble variant designs

    Membrane proteins are critical mediators for tumor progression and present enormous therapeutic potentials. Although gene profiling can identify their cancer-specific signatures, systematic correlations betwee...

    Lina Ma, Sitao Zhang, Qi Liang, Wenting Huang, Hui Wang, Emily Pan in BMC Bioinformatics (2023)

  5. Article

    Open Access

    Research on the effectiveness and safety of bronchial thermoplasty in patients with chronic obstructive pulmonary disease

    To investigate the clinical efficacy and safety of bronchial thermoplasty (BT) in treating patients with chronic obstructive pulmonary disease (COPD).

    Tao Wang, Peng Fu, Fa Long, Shengming Liu, Siyu Hu in European Journal of Medical Research (2023)

  6. Article

    Open Access

    The impact of serum copper on the risk of epilepsy: a mendelian randomization study

    The relationship between serum copper and epilepsy has been elucidated in observational studies. In this study, we aimed to explore the causal relationship between serum copper and epilepsy using Mendelian ran...

    Shihao Chen, Wenting Huang, Qi Xu, Tao He, Mulan Zhang, Huiqin Xu in Acta Epileptologica (2023)

  7. No Access

    Article

    Unsupervised domain adaptive tumor region recognition for Ki67 automated assisted quantification

    Ki67 is a protein associated with tumor proliferation and metastasis in breast cancer and acts as an essential prognostic factor. Clinical work requires recognizing tumor regions on Ki67-stained whole-slide im...

    Qiming He, Yiqing Liu, Feiyang Pan in International Journal of Computer Assisted… (2023)

  8. No Access

    Article

    A mutant R70V/E166A of short manganese peroxidase showing Mn2+-independent dye decolorization

    Il-MnP1, a short-type manganese peroxidase from Irpex lacteus F17, can oxidize some substrates in the absence of Mn2+, but the catalysis was much lower than in the presence of Mn2+. Here, we report a mutant R70V...

    Junli Wang, Jun Yang, Wenhan Huang, Wenting Huang in Applied Microbiology and Biotechnology (2023)

  9. Article

    Open Access

    Pulmonary sclerosing pneumocytoma containing spindle cells with sarcomatoid features: a case report with literature review

    Pulmonary sclerosing pneumocytoma (PSP) is an uncommon benign neoplasm originated from pneumocyte and PSP with malignant transformation is extremely rare.

    **g Liang, Qiang Du, **aoxing Ye, Wenting Huang in Diagnostic Pathology (2023)

  10. Article

    Open Access

    COVID-19 vaccine attitudes among a majority black sample in the Southern US: public health implications from a qualitative study

    The COVID-19 pandemic continues to have high caseloads in the US, with vaccines a critical component of the response. Disparities in COVID-19 morbidity and mortality have been identified across states and raci...

    Wenting Huang, Emily Dove-Medows, Jalissa Shealey, Katia Sanchez in BMC Public Health (2023)

  11. Article

    Open Access

    11β-HSD1 participates in epileptogenesis and the associated cognitive impairment by inhibiting apoptosis in mice

    Glucocorticoid signalling is closely related to both epilepsy and associated cognitive impairment, possibly through mechanisms involving neuronal apoptosis. As a critical enzyme for glucocorticoid action, the ...

    Xueying Li, Wanhua Qiu, Lu Deng, **g**g Lin in Journal of Translational Medicine (2022)

  12. No Access

    Article

    Health Effects of Religion, Spirituality, and Supernatural Beliefs in Mainland China: A Systematic Review

    Effects of religion, spirituality and supernatural beliefs (RSS) upon health in mainland China remain poorly understood, despite strong RSS beliefs influencing Chinese society. We conducted a Chinese–English b...

    Stephen W. Pan, Yuxin Liang, Shiqiang Wu, Wanqi Wang in Journal of Religion and Health (2022)

  13. Article

    Open Access

    Sporadic foveolar-type adenoma in gastric body/antrum junction with gastritis cystica profunda

    Sporadic gastric foveolar-type adenomas are extremely rare and are usually small, flat or slightly raised lesions that occur in the oxyntic mucosa.

    Jian Guan, Zhuo Li, Guihua Shen, Wenting Huang in BMC Gastroenterology (2022)

  14. Article

    Open Access

    HIV incidence among men who have sex with men in mainland China: a systematic review protocol

    Men who have sex with men (MSM) are disproportionately affected by HIV in China. Globally, younger MSM are at higher risk for incident HIV infections, but there has been substantial variation in the estimates ...

    Wenting Huang, Liming Wang, Mi Guodong, Ryan J. Zahn in Systematic Reviews (2021)

  15. No Access

    Article

    A potential probiotic bacterium for antipsychotic-induced metabolic syndrome: mechanisms underpinning how Akkermansia muciniphila subtype improves olanzapine-induced glucose homeostasis in mice

    Olanzapine (OLZ) is one of the most effective atypical antipsychotics but is associated with severe metabolic side effects, in which the gut microbiota plays an important role. Akkermansia muciniphila (A. mucinip...

    Dongquan Huang, Jie Gao, Chong Li, Caihong Nong, Wenting Huang in Psychopharmacology (2021)

  16. Article

    Open Access

    Evaluation of the immunomodulatory effects of anti-COVID-19 TCM formulae by multiple virus-related pathways

    Liansheng Qiao, Wenting Huang, **aoling Zhang in Signal Transduction and Targeted Therapy (2021)

  17. Article

    Open Access

    Adolescent and non-consensual anal sexual debut among Chinese men who have sex with men: a cross-sectional study

    Adolescent sexual debut and non-consensual sex have been linked to higher sexual risk and STI infection in adulthood among men who have sex with men (MSM) in high-income countries. This study aimed to examine ...

    Weiming Tang, Yehua Wang, Wenting Huang, Dan Wu, Fan Yang in BMC Infectious Diseases (2020)

  18. No Access

    Article

    Supernatural Explanatory Models of Health and Illness and HIV Antiretroviral Therapy Use Among Young Men Who Have Sex with Men in China

    In China, men who have sex with men (MSM) shoulder a disproportionate HIV burden. Early initiation and adherence to HIV antiretroviral therapy (ART) will be critical to reversing the HIV epidemic in China, but...

    Stephen W. Pan, M. Kumi Smith in International Journal of Behavioral Medici… (2020)

  19. Article

    Open Access

    DLBCL with amplification of JAK2/PD-L2 exhibits PMBCL-like CNA pattern and worse clinical outcome resembling those with MYD88 L265P mutation

    Recently, copy number alteration (CNA) of 9p24.1 were demonstrated in 10% of diffuse large b-cell lymphoma (DLBCL), with gene expression and mutation profiles that were similar to those of primary mediastinal ...

    Xuemin Xue, Wenting Huang, Tian Qiu, Lei Guo, Jianming Ying, Ning Lv in BMC Cancer (2020)

  20. Article

    Open Access

    The botanical origin and antioxidant, anti-BACE1 and antiproliferative properties of bee pollen from different regions of South Korea

    Bee pollen (BP) has been used as a traditional medicine and food diet additive due to its nutritional and biological properties. The potential biological properties of bee pollen vary greatly with the botanica...

    Yuchi Zou, Jian Hu, Wenting Huang, Liyun Zhu in BMC Complementary Medicine and Therapies (2020)

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