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Article
Open AccessOutdoor walking, genetic predisposition, and the risk of incident osteoporosis among older adults: A prospective large population-based cohort study
This large-scale prospective study showed that a significant association between longer duration of daily outdoor walking and reduced osteoporosis risk was found among older adults, particularly among those wi...
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Article
Meta-analysis reveals the effects of microbial inoculants on the biomass and diversity of soil microbial communities
Microbial inoculation involves transplanting microorganisms from their natural habitat to new plants or soils to improve plant performance, and it is being increasingly used in agriculture and ecological resto...
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Article
Sex differences in hemoglobin levels and five-year refracture risk in patients with osteoporotic fractures: a retrospective cohort analysis
We conducted a retrospective cohort analysis to examine the association between hemoglobin (Hb) levels and refracture risk in elderly patients with osteoporotic fractures (OPFs). Our findings suggest a nonline...
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Article
Open AccessRelationship between jejunum ATPase activity and antioxidant function on the growth performance, feed conversion efficiency, and jejunum microbiota in Hu sheep (Ovis aries)
ATPase activity and the antioxidant function of intestinal tissue can reflect intestinal cell metabolic activity and oxidative damage, which might be related to intestinal function. However, the specific influ...
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Article
Open AccessInhibition of glycolysis enhances the efficacy of immunotherapy via PDK-mediated upregulation of PD-L1
Immunotherapy for gastric cancer remains a challenge due to its limited efficacy. Metabolic reprogramming toward glycolysis has emerged as a promising avenue for enhancing the sensitivity of tumors to immunoth...
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Article
Open AccessU-shaped relationship found between fibrinogen-to-albumin ratio and systemic inflammation response index in osteoporotic fracture patients
The relationship between the Systemic Inflammatory Response Index (SIRI) and the Fibrinogen-to-albumin ratio (FAR) has not been extensively investigated. The objective of this study was to determine the indepe...
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Article
Open AccessIntegrated and DC-powered superconducting microcomb
Frequency combs, specialized laser sources emitting multiple equidistant frequency lines, have revolutionized science and technology with unprecedented precision and versatility. Recently, integrated frequency...
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Article
Open AccessRegulation of cerebral blood flow boosts precise brain targeting of vinpocetine-derived ionizable-lipidoid nanoparticles
Despite advances in active drug targeting for blood-brain barrier penetration, two key challenges persist: first, attachment of a targeting ligand to the drug or drug carrier does not enhance its brain biodist...
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Article
Influence of dry explosion combined with acid-spraying pretreatment on physicochemical and pyrolysis properties of Hybrid Pennisetum
A method of “dry chemical thermomechanical pretreatment” by combining dry explosion with acid-spraying was carried out for Hybrid Pennisetum (HP) to improve energy efficiency and reduce the negative environmental...
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Article
Open AccessAdvances in the application of extracellular vesicles derived from three-dimensional culture of stem cells
Stem cells (SCs) have been used therapeutically for decades, yet their applications are limited by factors such as the risk of immune rejection and potential tumorigenicity. Extracellular vesicles (EVs), a key...
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Article
Open AccessRelationship between lactate-to-albumin ratio and 28-day mortality in patients with exacerbation of chronic obstructive pulmonary disease admitted to the Intensive Care Unit
To explore the predictive value of lactate-to-albumin ratio (LAR) on 28-day mortality in patients with exacerbation of chronic obstructive pulmonary disease (AECOPD) admitted to the Intensive Care Unit (ICU).
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Article
Excitotoxic Storms of Ischemic Stroke: A Non-neuronal Perspective
Numerous neurological disorders share a fatal pathologic process known as glutamate excitotoxicity. Among which, ischemic stroke is the major cause of mortality and disability worldwide. For a long time, the m...
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Article
The treatment of petrochemical wastewater via ozone-persulfate coupled catalytic oxidation: mechanism of removal of soluble organic matter
Petrochemical wastewater contains a variety of organic pollutants. Advanced oxidation processes (AOPs) are used for deep petrochemical wastewater treatment with distinct advantages, including the complete mine...
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Article
Deterministic hierarchical joint remote state preparation via a non-maximally entangled state
The study of hierarchical quantum communication is of great importance in resolving practical scenarios involving multiple agents with varying permissions to access information. Inspired by the work (Shukla et...
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Article
Investigation of the impact of liquid presence on the acoustic streaming generated by a vibrating sharp tip capillary
Sharp edge structures have been demonstrated as an efficient way of generating acoustic streaming in microfluidic devices, which finds numerous applications in fluid mixing, pum**, particle actuation, and ce...
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Article
Open AccessPromoting green transportation through changing behaviors with low-carbon-travel function of digital maps
Climate change is a challenge for global sustainable development. The transportation sector contributes considerably to global greenhouse gas emissions. In China, it accounts for about 10% of total CO2 emissions ...
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Article
Open AccessEffect of remote ischemic preconditioning on postoperative cognitive dysfunction in adult patients with general anesthesia: a meta-analysis
Remote ischemic preconditioning (RIPC) is proven to have neuroprotective protective effects. Nevertheless, the impact of RIPC on postoperative cognitive dysfunction (POCD) in patients undergoing general anesth...
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Article
Brain glucose induces tolerance of Cryptococcus neoformans to amphotericin B during meningitis
Antibiotic tolerance is the ability of a susceptible population to survive high doses of cidal drugs and has been shown to compromise therapeutic outcomes in bacterial infections. In comparison, whether fungic...
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Article
Enhancing photodynamic inactivation via tunning spatial constraint on photosensitizer
The critical factor of spatial constraint, provided by the external confinement (e.g., matrix), is often overlooked during photodynamic inactivation, despite playing a crucial role in determining the molecular ph...
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Article
Cell senescence induced by toxic interaction between α-synuclein and iron precedes nigral dopaminergic neuron loss in a mouse model of Parkinson’s disease
Cell senescence has been implicated in the pathology of Parkinson’s disease (PD). Both abnormal α-synuclein aggregation and iron deposition are suggested to be the triggers, facilitators, and aggravators durin...
