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Article
In vivo affinity maturation of mouse B cells reprogrammed to express human antibodies
Mice adoptively transferred with mouse B cells edited via CRISPR to express human antibody variable chains could help evaluate candidate vaccines and develop better antibody therapies. However, current editing...
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Article
The phonological congruency modulated long-term form priming of Chinese characters
Elucidating the interaction between lexical processing and word learning is essential for a complete understanding of the underlying mechanisms of each of them. Long-term priming for words reflects an interpla...
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Article
Differential contrast guidance for aeroengine fault diagnosis with limited data
Data-driven methods have high requirements for data samples and the ideal state is to have sufficient samples and labels for model training. However, due to the limited sample of aeroengine fault data, existin...
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Article
Unlabelled LRET biosensor based on double-stranded DNA for the detection of anthraquinone anticancer drugs
Based on upconversion nanoparticles (UCNPs) as energy donor and herring sperm DNA (hsDNA) as molecular recognition element, an unlabelled upconversion luminescence (UCL) affinity biosensor was constructed for ...
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Article
Comparison and Evaluation of Two Combination Modes of Angiotensin for Establishing Murine Aortic Dissection Models
Aortic dissection (AD) is a potentially fatal cardiovascular emergency caused by separation of different layers of aortic wall. However, because of limited time window available for clinical research, there is...
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Article
Open AccessEffect of mRNA-LNP components of two globally-marketed COVID-19 vaccines on efficacy and stability
During the COVID-19 pandemic, Pfizer-BioNTech and Moderna successfully developed nucleoside-modified mRNA lipid nanoparticle (LNP) vaccines. SARS-CoV-2 spike protein expressed by those vaccines are identical i...
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Article
Tensile mechanical behavior and texture evolution of the weak texture Mg–1Al–0.5Mn–0.3Gd magnesium alloy
In this study, we utilized experiments and the Visco-plastic Self Consistent (VPSC) model to investigate the tensile mechanical behavior and texture evolution of the new weak texture Mg–1Al–0.5Mn–0.3Gd magnesi...
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Article
Microstructure and Tribological Properties of 7075-T651 Aluminum Alloy Affected by N-Ion Implantation
This research investigated the tribological properties and microstructure of 7075-T651 aluminum alloy after nitrogen ion implantation (N-ion implantation). Nitrogen ion was implanted into the surface layers of...
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Chapter and Conference Paper
Optimization Principle of Freight Train Operation Plan for Shenhua Railway
At present, the freight train formation plan cannot dynamically reflect the changes in freight demand in the transportation market, which makes it difficult to guide the actual transportation production work a...
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Article
Histones of Neutrophil Extracellular Traps Induce CD11b Expression in Brain Pericytes Via Dectin-1 after Traumatic Brain Injury
The brain pericyte is a unique and indispensable part of the blood-brain barrier (BBB), and contributes to several pathological processes in traumatic brain injury (TBI). However, the cellular and molecular me...
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Article
Development of SSR markers and genetic diversity analysis based on RAD-seq technology among Chinese populations of Daphnia magna
Daphnia magna belongs to the Cladocera order and plays an important role in the aquatic ecosystem. With the intensification of water pollution, the wild population of D. magna has declined rapidly in recent years...
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Article
Open AccessSplicing the active phases of copper/cobalt-based catalysts achieves high-rate tandem electroreduction of nitrate to ammonia
Electrocatalytic recycling of waste nitrate (NO3−) to valuable ammonia (NH3) at ambient conditions is a green and appealing alternative to the Haber−Bosch process. However, the reaction requires multi-step electr...
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Article
Development of 30 SNP markers for the Daphnia magna based on restriction-site associated DNA sequencing (RAD-seq)
Daphnia magna belongs to the Cladocera and plays an important role in the water ecosystem. With the intensification of water pollution, the wild population of D. magna has declined rapidly in recent years, and in...
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Article
The Pt/h-BN/BiOBr composite towards photocatalytic degradation of bisphenol A: the synergistic effect of h-BN and Pt
Semiconductor photocatalyst as a new type of green and sustainable energy material has extensively used in wastewater and gas treatment. In this work, we prepared Pt/h-BN/BiOBr composite by an alcohol-soluble ...
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Article
A reversible RNA on-switch that controls gene expression of AAV-delivered therapeutics in vivo
Widespread use of gene therapy technologies is limited in part by the lack of small genetic switches with wide dynamic ranges that control transgene expression without the requirement of additional protein com...
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Article
Magnitude and forming factors of mass elevation effect on Qinghai-Tibet Plateau
Mass elevation effect (MEE) refers to the thermal effect of huge mountains or plateaus, which causes the tendency for temperature-related montane landscape limits to occur at higher elevations in the inner mas...
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Chapter and Conference Paper
Research of the Lithium Battery-Based Energy Storage System for Light Rail Vehicle
Light rail is develo** very fast in China. With the help of battery-based energy storage system, the light rail vehicle will perform much better than before. Light rail vehicle energy storage system links li...
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Chapter and Conference Paper
Research on Application of Online UPS Topology in Novel Energy-Storage Traction Converter
This paper analyzed the online uninterruptible power supply (UPS) topology and compared the similarities and differences with the existing traction converter topology. Meanwhile, research on the bi-directiona...
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Chapter and Conference Paper
The Control Strategy Research of Hybrid EMU Energy Storage System
Because of its environmentally friendly, highly efficient, and multifunctional, the new hybrid EMU will have a broad space for development. Hybrid EMU ESS links lithium battery and intermediate DC bus together...