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    Article

    Influence of methane flow ratios on the structural and mechanical properties of Ti-doped diamond-like carbon films

    Diamond-like carbon films with Ti dopant (Ti-DLC) are synthesized by reactive magnetron sputtering using a pure Ti metal target. This study determines the effect of methane flow ratios (Rm=CH4/(Ar + CH4), ranging...

    Wei-Hsiang Lee, Chih-Chung Hu in The International Journal of Advanced Manu… (2023)

  2. Article

    Open Access

    Compositions of gut microbiota before and shortly after hepatitis C viral eradication by direct antiviral agents

    It is unclear whether dysbiosis in hepatitis C virus (HCV) infected patients results from the viral infection per se or develops as a result of hepatic dysfunction. We aimed to characterize compositions in gut...

    Yao-Chun Hsu, Chih-Cheng Chen, Wei-Hsiang Lee, Chi-Yang Chang in Scientific Reports (2022)

  3. Article

    Open Access

    Enterotype-based Analysis of Gut Microbiota along the Conventional Adenoma-Carcinoma Colorectal Cancer Pathway

    The dysbiosis of human gut microbiota is strongly associated with the development of colorectal cancer (CRC). The dysbiotic features of the transition from advanced polyp to early-stage CRC are largely unknown...

    Tzu-Wei Yang, Wei-Hsiang Lee, Siang-Jyun Tu, Wei-Chih Huang in Scientific Reports (2019)

  4. Article

    Open Access

    Ouroboros resembling competitive endogenous loop (ORCEL) in circular RNAs revealed through transcriptome sequencing dataset analysis

    Emerging evidence indicates that Circular RNAs (circRNAs) exert post-transcriptional regulation of gene expression. A subclass of circRNA was found enriched with miRNA target sites. This evidence suggests that...

    Yu-Chen Liu, Hsiao-Chin Hong, Chi-Dung Yang, Wei-Hsiang Lee, Hsin-Tzu Huang in BMC Genomics (2018)

  5. Article

    Open Access

    Bacterial alterations in salivary microbiota and their association in oral cancer

    Oral squamous cell carcinoma (OSCC) is the most common malignant neoplasm of the oral cavity and the fourth leading malignancy and cause of cancer-related death in the male population of Taiwan. Most cases are...

    Wei-Hsiang Lee, Hui-Mei Chen, Shun-Fa Yang, Chao Liang, Chih-Yu Peng in Scientific Reports (2017)

  6. No Access

    Article

    Specific roles for DEG/ENaC and TRP channels in touch and thermosensation in C. elegans nociceptors

    This study shows that a polymodal nociceptive sensory neuron in C. elegans detects both harsh body touch and noxious cold. Using calcium imaging and genetic tools, the researchers report that the same sensory neu...

    Marios Chatzigeorgiou, Sungjae Yoo, Joseph D Watson, Wei-Hsiang Lee in Nature Neuroscience (2010)