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Article
Netrin (UNC-6) mediates dendritic self-avoidance
Dendrites from the same neuron avoid each other through a mechanism involving cell surface proteins that trigger mutual repulsion. Here the authors show that the soluble axon guidance cue Netrin (UNC-6) drives...
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Article
Specific roles for DEG/ENaC and TRP channels in touch and thermosensation in C. elegans nociceptors
This study shows that a polymodal nociceptive sensory neuron in C. elegans detects both harsh body touch and noxious cold. Using calcium imaging and genetic tools, the researchers report that the same sensory neu...
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Article
Open AccessComplementary RNA amplification methods enhance microarray identification of transcripts expressed in the C. elegans nervous system
DNA microarrays provide a powerful method for global analysis of gene expression. The application of this technology to specific cell types and tissues, however, is typically limited by small amounts of availa...
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Article
Open AccessThe embryonic muscle transcriptome of Caenorhabditis elegans
The force generating mechanism of muscle is evolutionarily ancient; the fundamental structural and functional components of the sarcomere are common to motile animals throughout phylogeny. Recent evidence sugg...
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Article
Open AccessCell-specific microarray profiling experiments reveal a comprehensive picture of gene expression in the C. elegans nervous system
With its fully sequenced genome and simple, well-defined nervous system, the nematode Caenorhabditis elegans offers a unique opportunity to correlate gene expression with neuronal differentiation. The lineal orig...
