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  1. No Access

    Article

    Cell-Cell Interaction Disorders Associated with Senescence Can Be Repaired

    This minireview summarizes the data concerning the possibility of compensating for one of the senescence disorders. In hepatocyte cultures of old rats, compared to young ones, the ultradian protein synthesis r...

    V. Ya. Brodsky in Russian Journal of Developmental Biology (2020)

  2. No Access

    Article

    Mesenchymal stromal cells synchronize the rhythm of protein synthesis under the effect of an exogenous signal

    A comparative study was performed of dense 5-hour cultures of rat hepatocytes and equal-density cultures of mesenchymal stromal cells (MSC) isolated from human adipose tissue of rat bone marrow. The cells were...

    V. Ya. Brodsky, A. V. Vasil’ev, V. V. Terskikh… in Russian Journal of Developmental Biology (2012)

  3. No Access

    Article

    Melatonin injected into rat efficiently synchronizes the rhythm of protein synthesis in primary hepatocyte cultures isolated from this rat

    Melatonin injected intraperitoneally into rat synchronizes the ultradian rhythm of protein synthesis after 100 min in primary hepatocyte cultures isolated from this rat, which are studied after 1 or 2 days. Th...

    V. Ya. Brodsky, S. I. Rapoport, T. K. Dubovaya… in Russian Journal of Developmental Biology (2010)

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    Article

    In memory of Nikolai Grigor’evich Khrushchev (1932–2009)

    N. D. Ozernyuk, A. V. Vasil’ev, N. V. Nechaeva… in Russian Journal of Developmental Biology (2009)

  5. No Access

    Article

    The cell theory. Progress in studies on cell-cell communications

    Current data confirm the fundamental statement of the cell theory concerning the cell reproduction in a series of generations (omnis cellula e cellula). Cell communities or ensembles integrated by the signalin...

    V. Ya. Brodsky in Russian Journal of Developmental Biology (2009)

  6. No Access

    Article

    Melatonin synchronizes protein synthesis rhythm in hepatocyte cultures as an agonist of intercellular calcium and protein kinases

    Melatonin in nanomolar concentrations synchronizes protein synthesis in primary cultures of hepatocytes through calcium-dependent activation of protein kinases. The synchronizing effect of melatonin is blocked...

    V. Ya. Brodsky, V. A. Golichenkov… in Russian Journal of Developmental Biology (2009)

  7. No Access

    Article

    Direct cell-cell communications and social behavior of cells in mammals, protists, and bacteria. Possible causes of multicellularity

    Comparison of current data on direct cell-cell communications in mammals, protists, and bacteria suggests that the emergence of the signaling systems of self-organization underlay the emergence of multicellula...

    V. Ya. Brodsky in Russian Journal of Developmental Biology (2009)

  8. No Access

    Article

    To the memory of Tamara B. Aizenshtadt

    V. Ya. Brodsky, S. G. Vassetzky in Russian Journal of Developmental Biology (2008)

  9. No Access

    Article

    Melatonin promotes and synchronizes protein synthesis in hepatocyte culture from old rats

    The effect of 1 to 1000 nM melatonin was studied on daily cultures of rat hepatocytes on slides in serum-free medium. The minimum melatonin concentration (1 nM) proved to synchronize protein synthesis in async...

    V. Ya. Brodsky, V. A. Golichenkov… in Russian Journal of Developmental Biology (2008)

  10. No Access

    Article

    The 110th anniversary of the birth of Grigory Konstantinovich Khrushchov

    V. Ya. Brodsky in Russian Journal of Developmental Biology (2008)

  11. No Access

    Article

    Signaling factors of self-organization of protein synthesis rhythm in hepatocyte cultures—gangliosides and catecholamines function independently

    Considering the data on the low level of self-organization (self-synchronization) of protein synthesis rhythm in aging, we studied the possible interference of the signaling factors of self-organization, gangl...

    N. D. Zvezdina, L. A. Mal’chenko, V. I. Fateeva… in Russian Journal of Developmental Biology (2008)

  12. No Access

    Article

    100th anniversary of the birth of Evgenii Mikhailovich Brumberg

    V. Ya. Brodsky in Biology Bulletin (2007)

  13. No Access

    Article

    Mechanism of direct cell interactions. Self-organization of protein synthesis rhythm

    Primary 24-hour cultures of hepatocytes on slides in a serum-free medium were studied. Circahoralian rhythm of protein synthesis served as a marker of cell cooperation. Stimulation of protein kinase activities...

    V. Ya. Brodsky, N. D. Zvezdina, V. I. Fateeva… in Russian Journal of Developmental Biology (2006)

  14. No Access

    Article

    Aftereffect of synchronizers of protein synthesis rhythm in hepatocytes in vitro

    The effect of gangliosides and phenylephrine synchronizing the protein synthesis rhythm was preserved in hepatocytes cultured in the normal serum-free medium for one-two days. Hence, the membrane signal trigge...

    V. Ya. Brodsky, N. V. Nechaeva, N. D. Zvezdina… in Russian Journal of Developmental Biology (2006)

  15. No Access

    Article

    On the monograph lectures on the cell cycle by O. I. Epifanova (Moscow: KMK Scientific Press, 2003)

    V.Ya. Brodsky in Molecular Biology (2005)

  16. No Access

    Article

    Age-related features of protein synthesis rhythm. Effects of extracellular medium

    Cell interactions have been studied in cultures pf hepatocytes from young and old rats. The rhythm of protein synthesis is an index of cell interaction and synchronization in culture, while the amplitude of os...

    V. Ya. Brodsky, N. V. Nechaeva, N. D. Zvezdina… in Russian Journal of Developmental Biology (2005)

  17. No Access

    Article

    Cooperation of Hepatocytes in vitro in the Rhythm of Protein Synthesis is Promoted by the GM1 Ganglioside Contained in Vesicles and Liposomes

    The medium conditioned by dense, self-synchronized hepatocyte cultures was centrifuged at 150 000 g to obtain two fractions. The light fraction (supernatant fluid) contained ganglioside monomers and micelles, ...

    V. Ya. Brodsky, N. V. Nechaeva… in Biology Bulletin of the Russian Academy of… (2003)

  18. No Access

    Article

    Disturbed Cooperation of Hepatocytes in the Rhythm of Protein Synthesis by Chelating Agent of Cytoplasmic Calcium BAPTA-AM

    Previously we demonstrated synchronized oscillations of protein synthesis rate in hepatocyte cultures upon accumulation of monosialoganglioside GM1 in the medium or after introduction of exogenous GM1 to the m...

    N. D. Zvezdina, N. V. Nechaeva… in Biology Bulletin of the Russian Academy of… (2003)

  19. No Access

    Article

    Changes in Concentration of Calcium Ions and the Rhythm of Protein Synthesis in the Culture of Hepatocytes

    We studied the effects of the chelating agents of extra- and intracellular calcium ions, EGTA and BAPTA-AM, and of the inhibitor of Ca2+release from the reticulum, TMB-8, in the kinetics of protein synthesis in h...

    V. Ya. Brodsky, N. V. Nechaeva… in Biology Bulletin of the Russian Academy of… (2002)

  20. No Access

    Article

    Rhythm of Protein Synthesis in Cultures of Hepatocytes from Rats of Different Ages. Norm and Effect of the Peptide Lyvagen

    The circumhoralian rhythm of protein synthesis was determined in a monolayer culture of hepatocytes from rats at the age of 1 to 24 months and weighing from 45 to 480 g, respectively. The peptide lyvagen (Lys-...

    V. Ya. Brodsky, V. Kh. Khavinson… in Biology Bulletin of the Russian Academy of… (2001)

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