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  1. Article

    Open Access

    IL1R1+ cancer-associated fibroblasts drive tumor development and immunosuppression in colorectal cancer

    Fibroblasts have a considerable functional and molecular heterogeneity and can play various roles in the tumor microenvironment. Here we identify a pro-tumorigenic IL1R1+, IL-1-high-signaling subtype of fibroblas...

    E. Koncina, M. Nurmik, V. I. Pozdeev, C. Gilson, M. Tsenkova… in Nature Communications (2023)

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  2. Article

    Open Access

    IRF4 and BATF are critical for CD8+ T-cell function following infection with LCMV

    CD8+ T-cell functions are critical for preventing chronic viral infections by eliminating infected cells. For healthy immune responses, beneficial destruction of infected cells must be balanced against immunopath...

    M Grusdat, D R McIlwain, H C Xu, V I Pozdeev, J Knievel… in Cell Death & Differentiation (2014)

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  3. Article

    Open Access

    Reactive oxygen species delay control of lymphocytic choriomeningitis virus

    Cluster of differentiation (CD)8+ T cells are like a double edged sword during chronic viral infections because they not only promote virus elimination but also induce virus-mediated immunopathology. Elevated lev...

    P A Lang, H C Xu, M Grusdat, D R McIlwain, A A Pandyra… in Cell Death & Differentiation (2013)

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  4. No Access

    Article

    The light chain of the dynein complex DYNLRB1 interacts with NDP-kinase a from bovine retina

    R. M. Pagaev, D. L. Kakuev, V. I. Pozdeev… in Doklady Biochemistry and Biophysics (2012)

  5. No Access

    Article

    Haponin (EIF1AD) interacts with glyceraldehyde 3-phosphate dehydrohenase in the CHO-K1 cell line

    Haponin (HLDF-alike protein) was previously identified from the human promyelocytic leukemia HL-60 cell line. For the functional study of this protein, we obtained recombinant haponin with an N-terminal hexahisti...

    T. V. Rakitina, O. V. Bogatova, E. V. Smirnova… in Russian Journal of Bioorganic Chemistry (2010)