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  1. Article

    Open Access

    Remodeling of secretory lysosomes during education tunes functional potential in NK cells

    Inhibitory signaling during natural killer (NK) cell education translates into increased responsiveness to activation; however, the intracellular mechanism for functional tuning by inhibitory receptors remains...

    Jodie P. Goodridge, Benedikt Jacobs, Michelle L. Saetersmoen… in Nature Communications (2019)

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  2. Article

    Open Access

    Exome sequencing of primary breast cancers with paired metastatic lesions reveals metastasis-enriched mutations in the A-kinase anchoring protein family (AKAPs)

    Tumor heterogeneity in breast cancer tumors is today widely recognized. Most of the available knowledge in genetic variation however, relates to the primary tumor while metastatic lesions are much less studied...

    Una Kjällquist, Rikard Erlandsson, Nicholas P. Tobin, Amjad Alkodsi… in BMC Cancer (2018)

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  3. No Access

    Article

    Highly multiplexed and strand-specific single-cell RNA 5′ end sequencing

    Single-cell analysis of gene expression is increasingly important for the analysis of complex tissues, including cancer, develo** organs and adult stem cell niches. Here we present a detailed protocol for qu...

    Saiful Islam, Una Kjällquist, Annalena Moliner, Pawel Zajac… in Nature Protocols (2012)