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Article
Open AccessAnalysis of Plasmodium vivax schizont transcriptomes from field isolates reveals heterogeneity of expression of genes involved in host-parasite interactions
Plasmodium vivax gene regulation remains difficult to study due to the lack of a robust in vitro culture method, low parasite densities in peripheral circulation and asynchronous parasite development. We adapted ...
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Article
Author Correction: Genomes of all known members of a Plasmodium subgenus reveal paths to virulent human malaria
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Genomes of all known members of a Plasmodium subgenus reveal paths to virulent human malaria
Plasmodium falciparum, the most virulent agent of human malaria, shares a recent common ancestor with the gorilla parasite Plasmodium praefalciparum. Little is known about the other gorilla- and chimpanzee-infect...
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Article
Antibody-independent mechanisms regulate the establishment of chronic Plasmodium infection
Malaria is caused by parasites of the genus Plasmodium. All human-infecting Plasmodium species can establish long-lasting chronic infections1–5, creating an infectious reservoir to sustain transmission1,6. It is ...
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Article
Open AccessPlasmodium malariae and P. ovale genomes provide insights into malaria parasite evolution
The genome sequences of the neglected human-infective malaria species Plasmodium malariae and P. ovale provide new insights into their biology that are pertinent to understanding their epidemiology and to the bro...
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Article
Open AccessA comprehensive evaluation of rodent malaria parasite genomes and gene expression
Rodent malaria parasites (RMP) are used extensively as models of human malaria. Draft RMP genomes have been published for Plasmodium yoelii, P. berghei ANKA (PbA) and P. chabaudi AS (PcAS). Although availability ...
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Article
Open AccessGenome sequencing of chimpanzee malaria parasites reveals possible pathways of adaptation to human hosts
Plasmodium falciparum causes most human malaria deaths, having prehistorically evolved from parasites of African Great Apes. Here we explore the genomic basis of P. falciparum adaptation to human hosts by fully s...
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Article
Open AccessCharacterization and gene expression analysis of the cir multi-gene family of plasmodium chabaudi chabaudi (AS)
The pir genes comprise the largest multi-gene family in Plasmodium, with members found in P. vivax, P. knowlesi and the rodent malaria species. Despite comprising up to 5% of the genome, little is known about the...
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Article
Hot and sexy moulds!
The genus Aspergillus comprises a group of ubiquitous filamentous fungi for which more than 185 species have been described, including many human and plant pathogens, as well as industrially relevant organisms. R...
