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Article
Maternal asthma and asthma exacerbation during pregnancy and attention-deficit/hyperactivity disorder in offspring: a population-based cohort study
The link between inflammatory disorders, such as asthma, and attention deficit hyperactivity disorder (ADHD) is attracting increasing attention but few studies have examined cross-generational associations. We...
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Article
Open AccessIs Behçet’s syndrome associated with an increased risk of ischemic heart disease? A real-world evidence in Taiwan
A variety of chronic inflammatory diseases are linked to ischemic heart disease (IHD); however, this association is less well studied in patients with Behçet’s syndrome (BS). The primary objective of this stud...
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Article
Open AccessComparing the burdens of opportunistic infections among patients with systemic rheumatic diseases: a nationally representative cohort study
To estimate and compare the burdens of opportunistic infections and herpes zoster in real-world practice among patients with various systemic rheumatic diseases.
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Article
Open AccessIn vitro and in vivo effects of traditional Chinese medicine formula T33 in human breast cancer cells
Breast cancer is the leading cause of cancer-related death in women worldwide. Although traditional Chinese medicine (TCM) is commonly used by patients with breast cancer, little is known about TCM prescriptio...
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Article
Open AccessIncidence and survival impact of pulmonary arterial hypertension among patients with systemic lupus erythematosus: a nationwide cohort study
No population-based study has investigated the cumulative incidence of pulmonary arterial hypertension (PAH) in patients with newly diagnosed systemic lupus erythematosus (SLE) or the survival impact of PAH in...
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Article
Open AccessProteomic analyses and identification of arginine methylated proteins differentially recognized by autosera from anti-Sm positive SLE patients
Antibodies against spliceosome Sm proteins (anti-Sm autoantibodies) are specific to the autoimmune disease systemic lupus erythematosus (SLE). Anti-Sm autosera have been reported to specifically recognize Sm D...
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Article
Open AccessHuman parvovirus B19 nonstructural protein NS1 enhanced the expression of cleavage of 70 kDa U1-snRNP autoantigen
Human parvovirus B19 (B19) is known to induce apoptosis that has been associated with a variety of autoimmune disorders. Although we have previously reported that B19 non-structural protein (NS1) induces mitoc...
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Article
Open AccessIncreased expression of Matrix Metalloproteinase 9 in liver from NZB/W F1 mice received antibody against human parvovirus B19 VP1 unique region protein
Human parvovirus B19 infection has been postulated to the anti-phospholipid syndrome (APS) in autoimmunity. However, the influence of anti-B19-VP1u antibody in autoimmune diseases is still obscure.
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Article
Open AccessEffects of human parvovirus B19 VP1 unique region protein on macrophage responses
Activity of secreted phospholipase A (sPLA2) has been implicated in a wide range of cellular responses. However, little is known about the function of human parvovirus B19-VP1 unique region (VP1u) with sPLA2 a...
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Article
Japanese Encephalitis Virus Envelope Protein Mitigates TNF-α mRNA Expression in RAW264.7 Cells
Japanese encephalitis virus (JEV) is known as an important mosquito-borne human pathogen that causes Japanese encephalitis and may lead to lethal effect. Since monocyte has been demonstrated to play transmissi...
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Article
Anti-CENP-H antibodies in patients with Sjogren’s syndrome
Anti-centromere antibody (ACA) has been reported to be associated with Sjogren’s syndrome (SS) and the clinical significance of anti-CENP-H antibody remains unknown. To determine the clinical significance of a...
