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  1. No Access

    Article

    A Simple and Effective Method for Speciation Analysis of 13 Arsenic Species Using HPLC on a Fluorocarbon Stationary Phase Coupled to ICP-MS

    The separation properties of arsenic species was investigated using HPLC-ICP-MS with several commercially available fluorocarbon stationary phases and no ion-pair reagents in HPLC. One pentafluorophenyl column...

    Shin-ichi Miyashita, Kenji Kinoshita, Toshikazu Kaise in Analytical Sciences (2021)

  2. No Access

    Article

    Speciation of arsenic trioxide metabolites in blood cells and plasma of a patient with acute promyelocytic leukemia

    Arsenic trioxide (As2O3) has been widely accepted as the second-best choice for the treatment of relapsed and refractory acute promyelocytic leukemia (APL) patients. However, a few studies have been conducted on ...

    Yuta Yoshino, Bo Yuan, Shin-ich Miyashita… in Analytical and Bioanalytical Chemistry (2009)

  3. No Access

    Article

    Pharmacokinetics of arsenic species in Japanese patients with relapsed or refractory acute promyelocytic leukemia treated with arsenic trioxide

    To investigate the pharmacokinetics of arsenic species in Japanese patients with relapsed or refractory acute promyelocytic leukemia (APL) treated with arsenic trioxide (ATO) at a daily dose of 0.15 mg/kg.

    Shinya Fujisawa, Ryuzo Ohno, Kazuyuki Shigeno… in Cancer Chemotherapy and Pharmacology (2007)

  4. No Access

    Article

    The role of glutathione on the cytotoxic effects and cellular uptake of diphenylarsinic acid, a degradation product of chemical warfare agents

    The mechanism underlying enhancement of the cytotoxic effects of diphenylarsinic acid (DPAA) by sulfhydryl (SH) compounds, such as glutathione (GSH) and dimercaptopropane sulfonate (DMPS), was investigated in ...

    Takafumi Ochi, Kenji Kinoshita, Toshihide Suzuki… in Archives of Toxicology (2006)

  5. No Access

    Article

    Studies on materials containing polysaccharides as soil amendments 1: effects on animal waste water purification in a potting experiment

    A potting experiment was carried out to determine the effects of soil amendments containing polysaccharides and earthworms on a land application system for the purification of animal waste water. The following...

    Naoko Takada-Oikawa, Norihisa Katoh… in Journal of Material Cycles and Waste Manag… (2000)

  6. No Access

    Article

    Polymer-Mediated Extraction for Microplate Reader Spectrophotometric Determination of ppb-Level Copper(II) Ion in Water

    A negatively charged metal chelate, bis(bathocuproinedisulfonic acid)-copper(I), was formed and stably solubilized in an aqueous solution of a water-soluble polymer, poly(N-isopropylacrylamide) (PNIPAAm), at room...

    Tohru Saitoh, Masumi Haga, Teruaki Sakurai, Toshikazu Kaise… in Analytical Sciences (1998)

  7. No Access

    Article

    Dimethylarsinic acid causes apoptosis in HL-60 cells via interaction with glutathione

     Inducibility of apoptosis in cultured human HL-60 cells by arsenic compounds, such as arsenite, arsenate, methylarsonic acid (MAA), and dimethylarisinic acid (DMAA), was investigated, together with the role o...

    T. Ochi, Fumie Nakajima, Teruaki Sakurai, Toshikazu Kaise… in Archives of Toxicology (1996)

  8. No Access

    Article

    Degradation of arsenobetaine to inorganic arsenic by bacteria in seawater

    The substances suspended in seawater were fractionated by membrane filtration into three fractions. Fraction 1 was collected on a membrane filter of 0.22 µm pore-size, fraction 2 on a 5 µm pore-size and fracti...

    Ken'ichi Hanaoka, Osamu Nakamura, Hiroshi Ohno, Shoji Tagawa… in Hydrobiologia (1995)

  9. No Access

    Article

    The degradation of arsenobetaine to inorganic arsenic by sedimentary microorganisms

    Two growth media containing arsenobetaine [(CH3)3 As+ CH2COO−] were mixed with coastal marine sediments, the latter providing a source of microorganisms. The mixtures were kept at 25 °C in the dark and shaken for...

    Ken'ichi Hanaoka, Shoji Tagawa, Toshikazu Kaise in Hydrobiologia (1992)

  10. No Access

    Chapter and Conference Paper

    The degradation of arsenobetaine to inorganic arsenic by sedimentary microorganisms

    Two growth media containing arsenobetaine [(CH3)3 As +CH2COO- ] were mixed with coastal marine sediments, the latter providing a source of microorganisms. The mixtures were kept at 25 °C in the dark and shaken fo...

    Ken’ichi Hanaoka, Shoji Tagawa, Toshikazu Kaise in Sediment/Water Interactions (1992)

  11. No Access

    Article

    Metabolism and excretion of orally administered arsenobetaine in the hamster

    Hiroshi Yamauchi, Toshikazu Kaise… in Bulletin of Environmental Contamination an… (1986)