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  1. Article

    Open Access

    Analysis of risk factors for anastomotic leakage after lower rectal Cancer resection, including drain type: a retrospective single-center study

    We investigated the correlations between surgery-related factors and the incidence of anastomotic leakage after low anterior resection (LAR) for lower rectal cancer.

    Tetsushi Kinugasa, Sachiko Nagasu, Kenta Murotani, Tomoaki Mizobe in BMC Gastroenterology (2020)

  2. No Access

    Article

    Hydrolysis of Cellulose Selectively into Glucose Over Sulfonated Activated-Carbon Catalyst Under Hydrothermal Conditions

    A sulfonated activated-carbon (AC-SO3H) catalyst selectively hydrolyzes cellulose with β-1,4-glycosidic bonds into glucose in the catalytic hydrothermal reactions at temperatures around 423 K. The AC-SO3H catalys...

    Ayumu Onda, Takafumi Ochi, Kazumichi Yanagisawa in Topics in Catalysis (2009)

  3. No Access

    Article

    c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism

    c-Myc is an oncogene involved in many forms of cancer. Proteomic analysis of human P-493 B lymphoma cells and PC3 prostate cancer cells shows that c-Myc regulates the microRNAs miR-23a and miR-23b to increase ...

    ** Gao, Irina Tchernyshyov, Tsung-Cheng Chang, Yun-Sil Lee, Kayoko Kita in Nature (2009)

  4. No Access

    Article

    The role of glutathione on the cytotoxic effects and cellular uptake of diphenylarsinic acid, a degradation product of chemical warfare agents

    The mechanism underlying enhancement of the cytotoxic effects of diphenylarsinic acid (DPAA) by sulfhydryl (SH) compounds, such as glutathione (GSH) and dimercaptopropane sulfonate (DMPS), was investigated in ...

    Takafumi Ochi, Kenji Kinoshita, Toshihide Suzuki in Archives of Toxicology (2006)

  5. No Access

    Article

    Selenium metabolites in human urine after ingestion of selenite, L-selenomethionine, or DL-selenomethionine: a quantitative case study by HPLC/ICPMS

    To obtain quantitative information on human metabolism of selenium, we have performed selenium speciation analysis by HPLC/ICPMS on samples of human urine from one volunteer over a 48-hour period after ingesti...

    Doris Kuehnelt, Norbert Kienzl, Pedro Traar in Analytical and Bioanalytical Chemistry (2005)

  6. No Access

    Article

    Different effects of inorganic and dimethylated arsenic compounds on cell morphology, cytoskeletal organization, and DNA synthesis in cultured Chinese hamster V79 cells

    Changes in cytoskeletal organization of cultured V79 cells exposed to arsenite and dimethylarsinic acid (DMAA), a methylated derivative of inorganic arsenics, and related changes, such as mitotic arrest and i...

    Takafumi Ochi, Fumie Nakajima, Nobutaka Fukumori in Archives of Toxicology (1998)

  7. No Access

    Article

    Arsenic compound-induced increases in glutathione levels in cultured Chinese hamster V79 cells and mechanisms associated with changes in γ-glutamylcysteine synthetase activity, cystine uptake and utilization of cysteine

    Increases in the glutathione (GSH) level in cultured Chinese hamster V79 cells incubated with arsenic compounds were investigated in terms of changes in the activity of γ-glutamylcysteine synthetase (γ-GCS), ...

    Takafumi Ochi in Archives of Toxicology (1997)

  8. No Access

    Article

    Mechanism for the decrease in the accumulation of cadmium (Cd) in Cd-resistant Chinese hamster V79 cells

    The mechanism for the decrease in the accumulation of cadmium (Cd) in Cd-resistant Chinese hamster V79 (Cdr) cells in culture was investigated in a comparison with Cd-sensitive (Cds) cells. Both Cdr and Cds cells...

    Naoto Tsuchiya, Takafumi Ochi in Archives of Toxicology (1994)

  9. No Access

    Article

    Mechanism for the changes in levels of glutathione upon exposure of cultured mammalian cells to tertiary-butylhydroperoxide and diamide

    Qualitative and quantitative changes associated with cellular glutatione (GSH) in response to oxidants were investigated in cultured Chinese hamster V79 cells. Incubation of cells with benzoylperoxide (BZP), t...

    Takafumi Ochi in Archives of Toxicology (1993)

  10. No Access

    Chapter

    The Role of Active Oxygen and the Metabolism of Arachidonic Acid in the Formation of Clastogenic Factor by Human Monocytes

    The mouse skin tumor promoter phorbol-12-myristate-13-acetate (PMA) is a potent inflammatory agent that not only elicits the infiltration of neutrophils, monocytes and lymphocytes to the site of application (1...

    Walter Kozumbo, Dominique Muehlematter in Anticarcinogenesis and Radiation Protection (1987)