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  1. Article

    Reply to the Letter to the Editor: Quantitative evaluation of COVID-19 pneumonia severity by CT pneumonia analysis algorithm using deep learning technology and blood test results

    Tomohisa Okuma in Japanese Journal of Radiology (2021)

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  2. Article

    Quantitative evaluation of COVID-19 pneumonia severity by CT pneumonia analysis algorithm using deep learning technology and blood test results

    To evaluate whether early chest computed tomography (CT) lesions quantified by an artificial intelligence (AI)-based commercial software and blood test values at the initial presentation can differentiate the ...

    Tomohisa Okuma, Shinichi Hamamoto, Tetsunori Maebayashi… in Japanese Journal of Radiology (2021)

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    Article

    Survival Benefit of Radiofrequency Ablation with Intratumoral Cisplatin Administration in a Rabbit VX2 Lung Tumor Model

    This study evaluated the survival benefit of a combination therapy with radiofrequency ablation (RFA) and intratumoral cisplatin (ITC) administration for lung tumors by using a rabbit VX2 tumor model.

    Kazuki Murai, Shinichi Hamamoto… in CardioVascular and Interventional Radiology (2021)

  4. Article

    Open Access

    Combination therapy involving radiofrequency ablation and targeted chemotherapy with bevacizumab plus paclitaxel and cisplatin in a rabbit VX2 lung tumor model

    Radiofrequency ablation (RFA) is less effective for large tumors > 3 cm in diameter. Various studies of combination therapy using RFA and other treatments have been conducted to improve the results of RFA trea...

    Ai Ueki, Tomohisa Okuma, Shinichi Hamamoto, Ken Kageyama… in BMC Research Notes (2018)

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  5. Article

    Open Access

    Effective palliative radiofrequency ablation for tumors causing pain, numbness and motor function disorders: case series

    We present a case series of a palliative radiofrequency ablation (RFA) for the tumors that lead to the resolution of pain and motor function disorders. RFA is widely used on tumors in various organs and often ...

    Shinichi Hamamoto, Toshiyuki Matsuoka, Tomohisa Okuma, Akira Yamamoto… in BMC Research Notes (2014)

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  6. No Access

    Article

    Radiofrequency Ablation of Liver Tumors in Combination with Local OK-432 Injection Prolongs Survival and Suppresses Distant Tumor Growth in the Rabbit Model with Intra- and Extrahepatic VX2 Tumors

    To evaluate survival and distant tumor growth after radiofrequency ablation (RFA) and local OK-432 injection at a single tumor site in a rabbit model with intra- and extrahepatic VX2 tumors and to examine the ...

    Ken Kageyama, Akira Yamamoto, Tomohisa Okuma… in CardioVascular and Interventional Radiology (2013)

  7. No Access

    Article

    Determinants of Local Progression After Computed Tomography-Guided Percutaneous Radiofrequency Ablation for Unresectable Lung Tumors: 9-Year Experience in a Single Institution

    The purpose of this study was to retrospectively determine the local control rate and contributing factors to local progression after computed tomography (CT)-guided radiofrequency ablation (RFA) for unresecta...

    Tomohisa Okuma, Toshiyuki Matsuoka… in CardioVascular and Interventional Radiology (2010)

  8. No Access

    Article

    Chest wall temperature during radiofrequency ablation in a normal rabbit lung model

    The aim of this study was to examine the actual temperature during lung radiofrequency ablation (RFA) and pathological changes due to thermal damage in the pleural tissue of the chest wall in a rabbit model.

    Tomohisa Okuma, Toshiyuki Matsuoka, Akira Yamamoto… in Japanese Journal of Radiology (2010)

  9. No Access

    Article

    FDG-MicroPET and Diffusion-Weighted MR Image Evaluation of Early Changes After Radiofrequency Ablation in Implanted VX2 Tumors in Rabbits

    The objective of this study was to evaluate the early changes after radiofrequency ablation (RFA) in VX2 rabbit tumors implanted into the back muscles by diffusion-weighted magnetic resonance (MR) imaging and 18F...

    Tomohiro Ohira, Tomohisa Okuma… in CardioVascular and Interventional Radiology (2009)

  10. No Access

    Article

    Computed tomography-guided re-radiofrequency ablation for unresectable lung tumor with local progression previously treated with the same procedure

    The aim of this study was to evaluate the technical success, complications, and effectiveness of re-radiofrequency (re-RF) ablation for recurrent lung tumors previously treated with RF ablation.

    Tomohisa Okuma, Toshiyuki Matsuoka, Akira Yamamoto, Yoshimasa Oyama… in Radiation Medicine (2008)

  11. No Access

    Article

    Frequency and Risk Factors of Various Complications After Computed Tomography–Guided Radiofrequency Ablation of Lung Tumors

    To retrospectively determine the frequency and risk factors of various side effects and complications after percutaneous computed tomography–guided radiofrequency (RF) ablation of lung tumors.

    Tomohisa Okuma, Toshiyuki Matsuoka… in CardioVascular and Interventional Radiology (2008)

  12. No Access

    Article

    CT-guided radiofrequency ablation for lung cancer

    Recently, percutaneous radiofrequency (RF) ablation has been increasingly performed as a local treatment for lung malignancies. In RF ablation, the application of radiofrequency agitates ions in the tissues su...

    Toshiyuki Matsuoka, Tomohisa Okuma in International Journal of Clinical Oncology (2007)

  13. No Access

    Article

    Comparison of dynamic FDG-microPET study in a rabbit turpentine-induced inflammatory model and in a rabbit VX2 tumor model

    Purpose: We investigated the optimum time for the differentiation tumor from inflammation using dynamic FDG-microPET scans obtained by a MicroPET P4 scanner in animal models.Materials and...

    Yoshimasa Hamazawa, Koichi Koyama, Terue Okamura… in Annals of Nuclear Medicine (2007)

  14. No Access

    Article

    Fluorine- 18-fluorodeoxyglucose positron emission tomography for assessment of patients with unresectable recurrent or metastatic lung cancers after CT-guided radiofrequency ablation: Preliminary results

    We compared the diagnostic value of fluorine-18-fiuorodeoxyglucose positron emission tomography (FDG-PET) with that of computed tomography (CT) following radiofrequency ablation (RFA) of inoperable recurrent o...

    Tomohisa Okuma, Terue Okamura, Toshiyuki Matsuoka… in Annals of Nuclear Medicine (2006)

  15. No Access

    Article

    Radiofrequency Ablated Lesion in the Normal Porcine Lung: Long-Term Follow-Up with MRI and Pathology

    To evaluate the effectiveness of magnetic resonance imaging (MRI) in reflecting histopathologic changes after radiofrequency ablation (RFA) to the lung and to assess accurately the extent of tissue necrosis fo...

    Yoshimasa Oyama, Kenji Nakamura… in CardioVascular and Interventional Radiology (2005)