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Article
Open AccessAerobic exercise-induced HIF-1α upregulation in heart failure: exploring potential impacts on MCT1 and MPC1 regulation
The terminal stage of ischemic heart disease develops into heart failure (HF), which is characterized by hypoxia and metabolic disturbances in cardiomyocytes. The hypoxic failing heart triggers hypoxia-inducib...
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Article
Exercise training decreases lactylation and prevents myocardial ischemia–reperfusion injury by inhibiting YTHDF2
Exercise improves cardiac function and metabolism. Although long-term exercise leads to circulating and micro-environmental metabolic changes, the effect of exercise on protein post-translational lactylation m...
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Article
Supporting sustainable rural development through numerical simulation: a case study in Northwest China
The “Laochi” public space (LPS), which has existed for hundreds of years, has been gradually replaced by infrastructure during rural reconstruction. This study provides suggestions to protect the LPS with rura...
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Chapter and Conference Paper
Research on the Concept of Missile Cooperative Combat
At present, guided by the concept of system of operations, missile cooperative operation has become a new direction and new competitive point of missile weapon system development. Taking the US military as the...
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Chapter and Conference Paper
Application of GPS Technology in Missile Measurement and Control
GPS (Global Positioning System) is a new generation of precision satellite positioning system established with the rapid development of modern science and technology. It uses navigation satellites to measure t...
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Article
Open AccessRisk factors and predictive model for acute kidney Injury Transition to acute kidney disease in patients following partial nephrectomy
Acute kidney disease (AKD) is believed to be involved in the transition from acute kidney injury (AKI) to chronic kidney disease in general populations, but little is understood about this possibility among ki...
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Article
Open AccessBrain metabolism in Alzheimer’s disease: biological mechanisms of exercise
Alzheimer’s disease (AD) is a major subtype of neurodegenerative dementia caused by long-term interactions and accumulation of multiple adverse factors, accompanied by dysregulation of numerous intracellular s...
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Article
Open AccessMETTL14 is required for exercise-induced cardiac hypertrophy and protects against myocardial ischemia-reperfusion injury
RNA m6A modification is the most widely distributed RNA methylation and is closely related to various pathophysiological processes. Although the benefit of regular exercise on the heart has been well recognized, ...
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Article
Open AccessTreadmill exercise promotes E3 ubiquitin ligase to remove amyloid β and P-tau and improve cognitive ability in APP/PS1 transgenic mice
Moderate physical exercise is conducive to the brains of healthy humans and AD patients. Previous reports have suggested that treadmill exercise plays an anti-AD role and improves cognitive ability by promotin...
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Article
Open AccessGut microbiome mediates the protective effects of exercise after myocardial infarction
Gut microbiota plays important roles in health maintenance and diseases. Physical exercise has been demonstrated to be able to modulate gut microbiota. However, the potential role of gut microbiome in exercise...
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Article
The mechanism and prevention of mitochondrial injury after exercise
With the development of society, physical activity has come to be an effective means by which people pursue good health to improve the quality of life. However, with the increase of intensity and the passage o...
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Chapter and Conference Paper
Design of Gas Turbine State Data Acquisition Instrument Based on EEMD
In order to carry out the condition monitoring tasks in working process of gas turbine, a multi-channels data acquisition instrument was designed based on high-speed AD and FPGA, which can collect temperature,...
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Chapter
Circular RNAs in Metabolic Diseases
Metabolic diseases include diabetes mellitus (DM), obesity, metabolic syndrome, and non-alcoholic fatty liver disease (NAFLD). Circular RNA is a new type of RNA that is different from traditional linear RNA an...
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Chapter
Physical Exercise for Muscle Atrophy
The most direct characteristic of muscle atrophy is reduction in muscle mass, which is due to increased protein degradation or reduced protein synthesis in skeletal muscle. The loss of muscle mass can directly...
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Chapter
Circular RNAs as Novel Biomarkers for Cardiovascular Diseases
Cardiovascular diseases are among the most serious diseases, which are a leading cause of death across the world. Early diagnosis and prognosis prediction are keys for treatment and reduction of death rates. C...
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Article
Histone Acetylation Regulation in Sleep Deprivation-Induced Spatial Memory Impairment
Sleep disorders negatively affect cognition and health. Recent evidence has indicated that chromatin remodeling via histone acetylation regulates cognitive function. This study aimed to investigate the possibl...
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Article
Relative Sensitivity of Wetland Plants to SO2 Pollution
Sulfur dioxide (SO2) is a major air pollutant and its concentration is increasing in many metropolitan and industrial areas. Identification of SO2 tolerant species that can be used in wetland plantings in those a...
