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Article
Open AccessPreconditioning of the motor network with repetitive navigated transcranial magnetic stimulation (rnTMS) to improve oncological and functional outcome in brain tumor surgery: a study protocol for a randomized, sham-controlled, triple-blind clinical trial
The extent of resection of glioma is one of the most important predictors of the survival duration of patients after surgery. The presence of eloquent areas within or near a tumor often limits resection, as re...
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Article
Open AccessPersonalized surgical informed consent with stereoscopic visualization in neurosurgery—real benefit for the patient or unnecessary gimmick?
Informed consent of the patient prior to surgical procedures is obligatory. A good and informative communication improves patients’ understanding and confidence, thus may strengthen the patient-doctor relation...
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Article
Open AccessImplementation of a three-dimensional (3D) robotic digital microscope (AEOS) in spinal procedures
Three-dimensional exoscopes have been designed to overcome certain insufficiencies of operative microscopes. We aimed to explore the clinical use in various spinal surgeries. We performed surgery on patients w...
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Article
Open AccessDoes stereoscopic imaging improve the memorization of medical imaging by neurosurgeons? Experience of a single institution
Stereoscopic imaging has increasingly been used in anatomical teaching and neurosurgery. The aim of our study was to analyze the potential utility of stereoscopic imaging as a tool for memorizing neurosurgical...
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Article
Open AccessNetwork analysis shows decreased ipsilesional structural connectivity in glioma patients
Gliomas that infiltrate networks and systems, such as the motor system, often lead to substantial functional impairment in multiple systems. Network-based statistics (NBS) allow to assess local network differe...
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Article
Open AccessClinical implementation of a 3D4K-exoscope (Orbeye) in microneurosurgery
Exoscopic surgery promises alleviation of physical strain, improved intraoperative visualization and facilitation of the clinical workflow. In this prospective observational study, we investigate the clinical ...
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Article
Open AccessAugmented reality visualization in brain lesions: a prospective randomized controlled evaluation of its potential and current limitations in navigated microneurosurgery
Augmented reality (AR) has the potential to support complex neurosurgical interventions by including visual information seamlessly. This study examines intraoperative visualization parameters and clinical impa...
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Article
Open AccessRedefining standards—response to: introductions of technological innovations in neurosurgery
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Article
Open AccessMonitor-based exoscopic 3D4k neurosurgical interventions: a two-phase prospective-randomized clinical evaluation of a novel hybrid device
Promoting a disruptive innovation in microsurgery, exoscopes promise alleviation of physical strain and improved image quality through digital visualization during microneurosurgical interventions. This study ...
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Article
Open AccessDevelopment and initial evaluation of a novel simulation model for comprehensive brain tumor surgery training
Increasing technico-manual complexity of procedures and time constraints necessitates effective neurosurgical training. For this purpose, both screen- and model-based simulations are under investigation. Appro...
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Article
NTMS map** of non-primary motor areas in brain tumour patients and healthy volunteers
Navigated transcranial magnetic stimulation (nTMS) has been increasingly used for presurgical cortical map** of the primary motor cortex (M1) but remains controversial for the evaluation of non-primary motor...
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Article
Open AccessT2 map** of molecular subtypes of WHO grade II/III gliomas
According to the new WHO classification from 2016, molecular profiles have shown to provide reliable information about prognosis and treatment response. The purpose of our study is to evaluate the diagnostic p...
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Chapter and Conference Paper
VR Simulation of Novel Hands-Free Interaction Concepts for Surgical Robotic Visualization Systems
In microsurgery, visualization systems such as the traditional surgical microscope are essential, as surgeons rely on the highly magnified stereoscopic view for performing their operative tasks. For well-align...
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Article
Estimation of the resting motor threshold (RMT) in transcranial magnetic stimulation using relative-frequency and threshold-hunting methods in brain tumor patients
Application of transcranial magnetic stimulation is often based on the resting motor threshold. The aim of this study was to validate recent findings on the advantage of resting motor threshold estimation usin...
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Article
Open AccessManual for clinical language tractography
We introduce a user-friendly, standardized protocol for tractography of the major language fiber bundles.
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Article
TMS motor map** in brain tumor patients: more robust maps with an increased resting motor threshold
Navigated transcranial magnetic stimulation (nTMS) has found widespread usage across many clinical centers as part of their surgical planning routines. NTMS offers a non-invasive approach to delineation of the...
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Article
Left perisylvian tumor surgery aided by TMS language map** in a 6-year-old boy: case report
Awake surgery to preserve language function in young children is challenging, therefore reliable non-invasive work-up of language functional anatomy is needed to preserve language function at any cost. Further...
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Article
Correction to: Preservation of motor maps with increased motor evoked potential amplitude threshold in RMT determination
Funding information is added.
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Article
The impact of nTMS map** on treatment of brain AVMs
The treatment of brain arteriovenous malformations (BAVMs) is still contrarily discussed. Despite the debatable results of the ARUBA trial, most BAVMs still require treatment depending on the Spetzler-Martin (...
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Article
Preservation of motor maps with increased motor evoked potential amplitude threshold in RMT determination
Non-invasive pre-surgical map** of eloquent brain areas with navigated transcranial magnetic stimulation (nTMS) is a useful technique linked to the improvement of surgical planning and patient outcomes. The ...
