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Article
Aphasia and cognitive impairment decrease the reliability of rnTMS language map**
Navigated transcranial magnetic stimulation (nTMS) is a non-invasive map** tool to locate functional areas of the brain. While gaining importance in the preoperative planning process in motor eloquent region...
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Chapter
Transkranielle Magnetstimulation (TMS) in der Gliomchirurgie
Die transkranielle Magnetstimulation (TMS) ist die einzige nichtinvasive Methode zur schmerzlosen kortikalen Stimulation, die eine Untersuchung mittels elektrischer Stimulation erlaubt analog zum Goldstandard ...
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Article
Protocol for motor and language map** by navigated TMS in patients and healthy volunteers; workshop report
Navigated transcranial magnetic stimulation (nTMS) is increasingly used for preoperative map** of motor function, and clinical evidence for its benefit for brain tumor patients is accumulating. In respect to...
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Article
Brain tumors in eloquent areas: A European multicenter survey of intraoperative map** techniques, intraoperative seizures occurrence, and antiepileptic drug prophylaxis
Intraoperative map** and monitoring techniques for eloquent area tumors are routinely used world wide. Very few data are available regarding map** and monitoring methods and preferences, intraoperative sei...
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Article
Presurgical navigated TMS motor cortex map** improves outcome in glioblastoma surgery: a controlled observational study
The authors report on an observational study designed to isolate the impact of navigated transcranial magnetic stimulation (nTMS) on surgical outcome in glioblastoma treatment. We undertook a controlled observ...
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Article
Integration of navigated brain stimulation data into radiosurgical planning: potential benefits and dangers
Radiosurgical treatment of brain lesions near motor or language eloquent areas requires careful planning to achieve the optimal balance between effective dose prescription and preservation of function. Navigat...
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Article
Functional brain map** of patients with arteriovenous malformations using navigated transcranial magnetic stimulation: first experience in ten patients
Intracranial arteriovenous malformations (AVM) are known to be potent inductors of functional plasticity, and their vasculature makes standard functional imaging difficult. Here we conducted functional map**...
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Chapter
Comparison of Navigated Transcranial Magnetic Stimulation to Direct Electrical Stimulation for Map** the Motor Cortex Prior to Brain Tumor Resection
There are two main indications for map** of the motor cortex in patients eligible for surgery with rolandic tumors. First, map** is indicated if the functional anatomy (i.e. the exact spatial relationship ...
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Article
The preoperative use of navigated transcranial magnetic stimulation facilitates early resection of suspected low-grade gliomas in the motor cortex
Resection is recommended for low-grade gliomas, but often it is not performed if the tumor is suspected of invading the primary motor cortex. The study aim is to assess what influence preoperative navigated tr...
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Article
The reliability of topographic measurements from navigated transcranial magnetic stimulation in healthy volunteers and tumor patients
Navigated transcranial magnetic stimulation (nTMS) is increasingly being used for preoperative map** of the motor cortex. Any new technology should undergo rigorous validation before being widely adopted in ...
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Article
Assessing the functional status of the motor system in brain tumor patients using transcranial magnetic stimulation
Transcranial magnetic stimulation (TMS) is being used in the pre-operative diagnostics of patients with tumors in or near the motor cortex. Although the main purpose of TMS in such patients is to map the funct...
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Article
Plastic relocation of motor cortex in a patient with LGG (low grade glioma) confirmed by NBS (navigated brain stimulation)
We report on a patient with LGG, in whom NBS map** confirmed relocation of the primary motor cortex (M1) concurrent with multistage surgery. Comparing the NBS results at 18 months with the initial results re...
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Chapter
Preoperative Motor Map**
Neurosurgery must always carefully balance the benefit of surgical therapy against the risk of causing or increasing neurological symptoms. Preoperative risk assessment on the basis of standard anatomical imag...
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Article
Open AccessIdentification of diagnostic serum protein profiles of glioblastoma patients
Diagnosis of a glioblastoma (GBM) is triggered by the onset of symptoms and is based on cerebral imaging and histological examination. Serum-based biomarkers may support detection of GBM. Here, we explored ser...
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Chapter
Preoperative transcranial magnetic stimulation: Basic principles for map** a tumorous primary motor cortex
Soon after its introduction in the mid 1980s, TMS found widespread use in the neurosciences in general and was becoming an indispensable diagnostic tool in Neurology. By contrast, the Neurosurgical world only ...
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Article
Open AccessStudy on the clinical application of pulsed DC magnetic technology for tracking of intraoperative head motion during frameless stereotaxy
Tracking of post-registration head motion is one of the major problems in frameless stereotaxy. Various attempts in detecting and compensating for this phenomenon rely on a fixed reference device rigidly attac...