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Open AccessRandomized phase-III study of low-dose cytarabine and etoposide + /− all-trans retinoic acid in older unfit patients with NPM1-mutated acute myeloid leukemia
The aim of this randomized clinical trial was to evaluate the impact of all-trans retinoic acid (ATRA) in combination with non-intensive chemotherapy in older unfit patients (> 60 years) with newly diagnosed NPM1
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Article
Fieber, Vorhofflimmern und Angina pectoris bei einem 58-jährigen Patienten
Primär kardiale Lymphome (PCL) sind eine sehr seltene Entität kardialer Tumoren. Wir berichten über einen immunkompetenten 58-jährigen Mann mit Vorhofflimmern und rezidivierendem Fieber. In der umfassenden bil...
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Complete remission and successful stem cell mobilization after treatment of refractory plasma cell leukemia with bortezomib
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Article
Occlusion of central venous port catheters after simultaneous 24 h infusions of 5-fluorouracil and calcium-folinic acid in patients with gastrointestinal cancer
Folinic acid-modulated 5-FU regimens are standard elements in several chemotherapy combinations like FOLFIRI, FOLFOX, or AIO regimen in the palliative treatment of patients with gastrointestinal cancer. When t...
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Article
Diagnosis of invasive fungal infections in hematology and oncology
Invasive fungal infections are a primary cause of morbidity and mortality in patients with hematological malignancies. Establishing a definite diagnosis of invasive fungal infection in febrile neutropenic pati...
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Chapter
Dünndarmtumoren
Dünndarmtumoren sind benigne oder maligne Tumoren, die primär im Duodenum, Jejunum oder Ileum entstehen. Davon zu trennen sind sekundäre Tumoren, also Metastasen.
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Chapter
Analkarzinom
Die Gruppe der Analkarzinome umfaßt alle malignen epithelialen Tumoren, die zwischen dem äußeren Analring und dem Beckenboden im Analkanal entstehen.
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Chapter
Ösophagustumoren
Die benignen Ösophagustumoren sind epithelialen oder mesenchymalen Ursprungs.
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Article
Reply to Ø Bruserud: Increases of sICAM-1 in neutropenic fever
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Increases of sICAM-1 during neutropenic pneumonia in leukemic patients
Aggressive chemotherapy of leukemia increases the risk of severe infections during treatment-induced myelosuppression. However, the assessment of an infectious origin of neutropenic fever is often difficult. L...
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Article
Neutrophilic dermal infiltrates in granulocytopenic patients with acute leukemia
Acute febrile neutrophilic dermatosis (AFND, Sweet's syndrome) is clinically characterized by fever, neutrophilic leukocytosis, and tender dermal plaques. Histological examination typically reveals infiltratio...
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Article
Fibrinolytic mechanisms in tumor growth and spreading
The high prevalence of hypercoagulative states in cancer patients has been known for more than a century. Venous thrombosis in gastric cancer was described by Trousseau in 1865 [55]. In 1878, Billroth observed...
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Article
Retinoic acid in the treatment of acute promyelocytic leukemia: Inefficacy of the 13-cis isomer and induction of complete remission by the all-trans isomer complicated by thromboembolic events
The clinical course of three patients with acute promyelocytic leukemia receiving all-trans retinoic acid (ATRA) as a single agent is reported. The first two patients were in first and second relapse of their leu...
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Abstract