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  1. No Access

    Article

    Multiple-slice magnetic resonance imaging can detect visceral adipose tissue reduction more accurately than single-slice imaging

    Imaging methods by magnetic resonance imaging are being increasingly used to quantify visceral adipose tissue (VAT), but there is no clear consensus as to a standardized protocol. We compared the ability of tw...

    R So, H Sasai, T Matsuo, T Tsujimoto, M Eto in European Journal of Clinical Nutrition (2012)

  2. No Access

    Article

    Long-term stable obesity increases risk of hypertension

    Although some prospective cohort studies have shown that baseline BMI is positively associated with a future incident risk for hypertension, these studies do not account for weight changes during the observati...

    T Matsuo, T Sairenchi, K Suzuki, K Tanaka, T Muto in International Journal of Obesity (2011)

  3. No Access

    Article

    An increase in high-density lipoprotein cholesterol after weight loss intervention is associated with long-term maintenance of reduced visceral abdominal fat

    It is generally agreed that excess abdominal fat, in particular visceral abdominal fat (VAF), is related to an increased risk for obesity-related complications. We examined the association between metabolic ri...

    T Matsuo, Y Kato, Y Murotake, M-K Kim, H Unno, K Tanaka in International Journal of Obesity (2010)

  4. No Access

    Article

    Indirect lifestyle intervention through wives improves metabolic syndrome components in men

    It is well known that body weight loss through a direct (supervised) lifestyle intervention (LSI) improves obesity-related metabolic disorders. The purpose of this study was to investigate the effects of an in...

    T Matsuo, M K Kim, Y Murotake, S Numao, M J Kim in International Journal of Obesity (2010)

  5. No Access

    Article

    Effects of obesity phenotype on fat metabolism in obese men during endurance exercise

    The effects of obesity phenotype on fat metabolism during endurance exercise are unclear. This study aimed to investigate in obese men whether body fat distribution would influence plasma fat availability and ...

    S Numao, Y Hayashi, Y Katayama, T Matsuo, T Tomita in International Journal of Obesity (2006)

  6. No Access

    Article

    The percentage of myeloperoxidase-positive blast cells is a strong independent prognostic factor in acute myeloid leukemia, even in the patients with normal karyotype

    To examine whether the percentage of myeloperoxidase (MPO)-positive blast cells is useful as a prognostic factor for acute myeloid leukemia (AML), cytochemical analysis of MPO was performed in 491 patients who...

    T Matsuo, K Kuriyama, Y Miyazaki, S Yoshida, M Tomonaga, N Emi, T Kobayashi in Leukemia (2003)

  7. No Access

    Chapter and Conference Paper

    Growth of Leukemic Progenitor Cells of Acute Lymphoblastic Leukemia in Co-Culture with Murine Stromal Cell Line MS-5

    We developed a new semi-quantitative assay method for leukemic progenitor cells of patients with acute lymphoblastic leukemia (ALL) by employing a xenogenic co-culturing system with murine bone marrow-derived ...

    I. **nai, K. Nagai, Y. Kawaguchi, F. Yagasaki, Y. Yakata, T. Matsuo in Acute Leukemias IX (2003)

  8. No Access

    Article

    Chemotherapy targeting methylthioadenosine phosphorylase (MTAP) deficiency in adult T cell leukemia (ATL)

    Methylthioadenosine phosphorylase (MTAP) is an important enzyme used for the salvage of adenine and methionine. Cells lacking this enzyme are expected to be sensitive to purine synthesis inhibitors and/or meth...

    H Harasawa, Y Yamada, M Kudoh, K Sugahara, H Soda, Y Hirakata, H Sasaki in Leukemia (2002)

  9. No Access

    Article

    Clinical implications of leptin and its potential humoral regulators in long-term low-calorie diet therapy for obese humans

    Objective: To address the clinical implications of leptin and to re-examine the relationship between leptin and its potential humoral regulators such as insulin, nonesterified fatty acids (NEFA) and triiodothyron...

    T Miyawaki, H Masuzaki, Y Ogawa, K Hosoda in European Journal of Clinical Nutrition (2002)

  10. No Access

    Article

    Effect of a selective Abl tyrosine kinase inhibitor, STI571, on in vitro growth of BCR-ABL-positive acute lymphoblastic leukemia cells

    By employing a new semi-quantitative assay system that includes co-culturing leukemia cells with the mouse bone marrow-derived stromal cell line MS-5, we examined the suppressive effect of a selective inhibito...

    Y Kawaguchi, I **nai, K Nagai, F Yagasaki, Y Yakata, T Matsuo, K Kuriyama in Leukemia (2001)

  11. No Access

    Article

    Allogeneic bone marrow transplantation improves the outcome of de novo AML with trilineage dysplasia (AML-TLD)

    De novo acute myeloid leukemia (AML) with dysplastic features in erythroblasts, granulocytes and megakaryocytes, similar to those in myelodysplastic syndrome (MDS) has been described as AML with trilineage dyspla...

    J Taguchi, Y Miyazaki, S Yoshida, T Fukushima, Y Moriuchi, I **nai, T Matsuo in Leukemia (2000)

  12. No Access

    Article

    Colony-forming unit-megakaryocyte (CFU-meg) numbers and serum thrombopoietin concentrations in thrombocytopenic disorders: an inverse correlation in myelodysplastic syndromes

    We studied both serum-free colony-forming unit-megakaryocyte (CFU-meg) numbers and serum thrombopoietin (TPO) levels in 14 patients with aplastic anemia (AA), 37 patients with myelodysplastic syndromes (MDS) a...

    W Wang, T Matsuo, S Yoshida, H Mori, Y Miyazaki, K Kuriyama, M Tomonaga in Leukemia (2000)

  13. No Access

    Article

    New system for assessing the prognosis of refractory anemia patients

    Refractory anemia (RA) is a very heterogeneous disease regarding biological and clinical features. The International Prognostic Scoring System (IPSS) was useful for assessing the prognosis in the whole group o...

    A Matsuda, I **nai, F Yagasaki, S Kusumoto, I Murohashi, M Bessho, K Hirashima in Leukemia (1999)

  14. No Access

    Article

    Serum arginine level in neonatal citrullinaemia

    M. Matsoo, H. Takemine, M. Aida, H. Nakamura in Journal of Inherited Metabolic Disease (1988)

  15. No Access

    Article

    Cockayne syndrome: Magnetic resonance images of the brain in a severe form with early onset

    A 2-year-old boy with an early onset and severe form of Cockayne's syndrome (CS) showed differences from the common CS form, which made the clinical diagnosis difficult. However, the cellular characteristics o...

    H. Nishio, S. Kodama, T. Matsuo, M. Ichihashi in Journal of Inherited Metabolic Disease (1988)

  16. No Access

    Article

    Citrullinaemia: an infantile form withp-hydroxyphenylpyruvic andp-hydroxyphenyllactic acidurias

    M. Matsuo, K. Saiki, J. Tanabe, H. Nakamura in Journal of Inherited Metabolic Disease (1987)

  17. No Access

    Article

    Transient hyperphenylalaninaemia with a high neopterin to biopterin ratio in urine

    A case of transient hyperphenylalaninaemia with a maturational delay of dihydropteridine synthesis is described. With the Guthrie test, the patient showed a blood phenylalanine level of 38 mg dl−1, which had fall...

    T. Takahashi, S. Kodama, H. Nishio, T. Takumi in Journal of Inherited Metabolic Disease (1985)

  18. Article

    Congenitally impaired hormone sensitivity of the adipose tissue of spontaneously diabetic mice, KK

    Adipose tissue of KK mice was less sensitive to insulin in its stimulatory action on glucose oxidation or its inhibitory action on lipolysis, and to epinephrine in its stimulatory action on lipolysis as compar...

    H. Iwatsuka, S. Taketomi, T. Matsuo, Z. Suzuoki in Diabetologia (1974)

  19. Article

    Structural changes of pancreatic islets in genetically obese rats

    Light and electron microscopic observations were performed on pancreatic islets from genetically obese rats, (Zucker, “fatty”), from 5 to 52 weeks of age. At 5 weeks of age, islets were moderately hypertrophie...

    A. Shino, T. Matsuo, H. Iwatsuka, Z. Suzuoki in Diabetologia (1973)

  20. Article

    Induction of diabetic alterations by goldthioglucose-obesity in KK, ICR and C57BL mice

    The effect of goldthioglucose (GTG) obesity on development of diabetes was investigated in genetically diabetic (KK) and normal (ICR and C57BL) mice. GTG obesity intensified diabetic traits in KK mice from che...

    T. Matsuo, A. Shino in Diabetologia (1972)