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Article
A Japanese Multicenter Study on PET and Other Biomarkers for Subjects with Potential Preclinical and Prodromal Alzheimer’s Disease
PET (positron emission tomography) and CSF (cerebrospinal fluid) provide the “ATN” (Amyloid, Tau, Neurodegeneration) classification and play an essential role in early and differential diagnosis of Alzheimer’s...
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Article
Open AccessTerahertz-field-induced polar charge order in electronic-type dielectrics
Ultrafast electronic-phase change in solids by light, called photoinduced phase transition, is a central issue in the field of non-equilibrium quantum physics, which has been developed very recently. In most o...
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Chapter and Conference Paper
Energetic Consideration on the Occurrence Condition of Self-Synchronization in Two Unbalanced Rotors
When synchronization occurs in a system in which several nonlinear self-excited oscillators with different natural frequencies are coupled, the frequencies of all of the oscillators are entrained due to their ...
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Article
Open Accessα-PD-1 therapy elevates Treg/Th balance and increases tumor cell pSmad3 that are both targeted by α-TGFβ antibody to promote durable rejection and immunity in squamous cell carcinomas
Checkpoint blockade immunotherapy has improved metastatic cancer patient survival, but response rates remain low. There is an unmet need to identify mechanisms and tools to circumvent resistance. In human pati...
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Article
Strange metal from a frustration-driven charge order instability
Interparticle interactions are self-conflicting rather than cooperative on particular lattices. When such geometrical frustration occurs, charge ordering (CO) can be destabilized into non-trivial charge states...
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Article
Resolve Instrument on X-ray Astronomy Recovery Mission (XARM)
The X-ray Astronomy Recovery Mission (XARM) is a recovery mission of ASTRO-H/Hitomi, which is expected to be launched in Japanese Fiscal Year of 2020 at the earliest. The Resolve instrument on XARM consists of an...
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Article
Open AccessQuantum-disordered state of magnetic and electric dipoles in an organic Mott system
Strongly enhanced quantum fluctuations often lead to a rich variety of quantum-disordered states. Develo** approaches to enhance quantum fluctuations may open paths to realize even more fascinating quantum s...
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Article
Endocytosis following dopamine D2 receptor activation is critical for neuronal activity and dendritic spine formation via Rabex-5/PDGFRβ signaling in striatopallidal medium spiny neurons
Aberrant dopamine D2 receptor (D2R) activity is associated with neuropsychiatric disorders, making those receptors targets for antipsychotic drugs. Here, we report that novel signaling through the intracellularly...
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Article
Somatic PHF6 mutations in 1760 cases with various myeloid neoplasms
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Article
Open AccessDetection of one-dimensional migration of single self-interstitial atoms in tungsten using high-voltage electron microscopy
The dynamic behaviour of atomic-size disarrangements of atoms—point defects (self-interstitial atoms (SIAs) and vacancies)—often governs the macroscopic properties of crystalline materials. However, the dynami...
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Article
Open AccessNovel electronic ferroelectricity in an organic charge-order insulator investigated with terahertz-pump optical-probe spectroscopy
In electronic-type ferroelectrics, where dipole moments produced by the variations of electron configurations are aligned, the polarization is expected to be rapidly controlled by electric fields. Such a featu...
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Article
Open AccessErratum: Intracellular amyloid β oligomers impair organelle transport and induce dendritic spine loss in primary neurons
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Article
Phase transition of sigma-CrFe under fast electron irradiation
Preparation of a sigma-CrFe single-phase specimen was achieved by arc melting of pure Fe and Cr, cold rolling, and subsequent annealing at 973 K or 1073 K in vacuum. Cold rolling before annealing is effective ...
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Article
Predictive role of levels of soluble interleukin-2 receptor and C-reactive protein in selecting autologous PBSC transplantation for lymphoma
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Article
Irradiation-induced ordering in Pt-Cu alloy focusing on Pt7Cu
The existence of Pt7Cu ordering phase (intermetallic compound) was investigated by ab initio calculations and high voltage electron microscopy (HVEM) focusing on irradiationinduced ordering. The Pt7Cu ordering ph...
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Article
Sindrome metabolica, obesità e neoplasie gastrointestinali
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Article
EED mutants impair polycomb repressive complex 2 in myelodysplastic syndrome and related neoplasms
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Article
A nonsense mutation of IDH1 in myelodysplastic syndromes and related disorders
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Chapter and Conference Paper
Fingertip Synchrotron Radiation Angiography for Prediction of Diabetic Microangiopathy
Diabetic microangiopathy causes acetylcholine-induced paradoxical vasoconstriction in arterioles (20-200 μm). Because conventional angiographic systems lack sufficient spatial resolution (100-200 μm), they are no...
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Article
Carcinoid tumors of the pancreas: dynamic CT and MRI features with pathological correlation
Carcinoid tumor of the pancreas is rare, and there are few reports that described its CT or magnetic resonance imaging (MRI) findings. We describe the characteristic CT and MRI findings in four cases of carcin...
