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  1. No Access

    Article

    Development of Simple, Objective Chair-Standing Assessment of Physical Function in Older Individuals Using a Kinect™ Sensor

    With increasing interest in addressing quality of life of older individuals, tests such as the Functional Independence Measure (FIM) are widely used measures of infirmity and burden of care. However, these sca...

    Nobuo Takeshima, T. Kohama, M. Kusunoki, E. Fujita in The Journal of Frailty & Aging (2019)

  2. No Access

    Article

    Sphingosine kinase-1 is a downstream regulator of imatinib-induced apoptosis in chronic myeloid leukemia cells

    We examined the involvement of sphingosine kinase-1 (SphK1), which governs the ceramide/sphingosine-1-phosphate balance, in susceptibility to imatinib of either sensitive or resistant chronic myeloid leukemia ...

    E Bonhoure, A Lauret, D J Barnes, C Martin, B Malavaud, T Kohama, J V Melo in Leukemia (2008)

  3. No Access

    Article

    Overcoming MDR-associated chemoresistance in HL-60 acute myeloid leukemia cells by targeting shingosine kinase-1

    We examined the involvement of sphingosine kinase-1, a critical regulator of the sphingolipid balance, in susceptibility to antineoplastic agents of either sensitive or multidrug-resistant acute myeloid leukem...

    E Bonhoure, D Pchejetski, N Aouali, H Morjani, T Levade, T Kohama, O Cuvillier in Leukemia (2006)

  4. No Access

    Article

    Heavy ion collisions at collider energies—Insights from PHENIX

    A. Drees, K. Adcox, S. S. Adler, N. N. Ajitanand, Y. Akiba, J. Alexander in Pramana (2003)

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    Article

    Deuteron and triton production with high energy sulphur and lead beams

    Proton and deuteron production has been observed in S+S and S+Pb collisions at 200 A \(\cdot\) GeV and in Pb+Pb reactions at 158 A \(\cdot\) GeV at...

    I.G. Bearden, H. Bøggild, J. Boissevain in The European Physical Journal C - Particle… (2002)

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    Article

    First results from RHIC-PHENIX

    The PHENIX experiment consists of a large detector system located at the newly commissioned relativistic heavy ion collider (RHIC) at the Brookhaven National Laboratory. The primary goal of the PHENIX experime...

    Tarun Kanti Ghosh, K Adcox, S S Adler, N Ajitanand, Y Akiba, J Alexander in Pramana (2001)

  7. No Access

    Article

    Space-time evolution of the hadronic source in peripheral to central Pb+Pb collisions

    Two-particle correlations of negative pions as a function of charged particle multiplicity are studied in Pb+Pb collisions at \(\sqrt{s}=17.3\) GeV per nucleon using the NA44 exp...

    I.G. Bearden, H. Bøggild, J. Boissevain in The European Physical Journal C - Particle… (2000)

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    Article

    Extensive lymphopenia due to apoptosis of uninfected lymphocytes in acute measles patients

     Infection with measles virus induces a transient immunosuppression, which occasionally results in fatal opportunistic infections. To obtain fundamental information about the mechanism, we examined peripheral ...

    H. Okada, F. Kobune, T. A. Sato, T. Kohama, Y. Takeuchi, T. Abe in Archives of Virology (2000)

  9. No Access

    Chapter and Conference Paper

    The Eradication of the Melon Fly from the Okinawa Islands, Japan: II. Current Control Program

    The Okinawa Prefecture, Japan, consists of groups of islands: the Okinawa islands (143,322 ha). On Kume island nearby Okinawa island, an experimental melon fly eradication project was started in 1972 using SIT...

    H. Kakinohana, H. Kuba, M. Yamagishi, T. Kohama, K. Kinjyo, A. Tanahara in Fruit Flies (1993)

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    Article

    Intracellular processing of measles virus fusion protein

    Intracellular processing of measles virus fusion (F) protein was studied by radiolabeling and immunoprecipitation with a monoclonal antibody against F protein. The cleavage of F protein into F1 and F2 subunits wa...

    T. A. Sato, T. Kohama, A. Sugiura in Archives of Virology (1988)

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    Article

    Protective effect of antibodies to two viral envelope glycoproteins on lethal infection with Newcastle disease virus

    The protective effect of humoral immunity against lethal infection of chickens with Newcastle disease virus was studied.

    Y. Umino, T. Kohama, M. Kohase, A. Sugiura, H. -D. Klenk, R. Rott in Archives of Virology (1987)

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    Article

    Effect of carboxylic ionophores on measles virus hemagglutinin protein

    We have studied the effect of two carboxylic ionophores, monensin and laidlomycin, on the replication of measles virus in KB cells. The yield of infectious virus was markedly depressed at the concentrations of...

    T. Kohama, A. Fukuda, A. Sugiura in Archives of Virology (1986)

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    Article

    Maturation of measles virus hemagglutinin glycoprotein

    The processing of measles virus hemagglutinin glycoprotein (H) in infected cells was studied by pulse-chase method and two-dimensional isoelectric focusing and SDS-polyacrylamide slab gel electrophoresis. H gl...

    T. Kohama, T. A. Sato, F. Kobune, A. Sugiura in Archives of Virology (1985)

  14. Article

    Biological functions of monospecific antibodies to envelope glycoproteins of Newcastle disease virus

    Monospecific antisera to HN and F glycoproteins of Newcastle disease virus were prepared, and their effects on the biological activities of the virus were investigated. Anti-HN serum inhibited hemagglutinating...

    Y. Umino, T. Kohama, M. Kohase, A. Sugiura, H. -D. Klenk, R. Rott in Archives of Virology (1984)

  15. No Access

    Chapter and Conference Paper

    Proteolysis, a Determinant for Virus Pathogenicity

    Pathogenicity, i.e., the ability of a virus to induce disease in the infected organism, is the result of a complex interplay of a multitude of factors that are determined by the biological, biochemical, and ge...

    H. D. Klenk, F. X. Bosch, W. Garten, T. Kohama in Biological Functions of Proteinases (1979)