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  1. Article

    Open Access

    Circulating sphingosine-1-phosphate and erythrocyte sphingosine kinase-1 activity as novel biomarkers for early prostate cancer detection

    Current markers available for screening normal populations and for monitoring prostate cancer (PCa) treatment lack sensitivity and selectivity. Sphingosine-1-phosphate (S1P) is a circulating lipid second messe...

    J Nunes, M Naymark, L Sauer, A Muhammad, H Keun, J Sturge… in British Journal of Cancer (2012)

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  2. Article

    Open Access

    Inflammatory cytokines and aromatase inhibitor-associated musculoskeletal syndrome: a case–control study

    The aromatase inhibitor (AI)-associated musculoskeletal syndrome (AIMSS) occurs in approximately 50% of AI-treated patients. Inflammatory mediators are associated with oestrogen signalling and may change with ...

    N L Henry, D Pchejetski, R A'Hern, A T Nguyen, P Charles… in British Journal of Cancer (2010)

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  3. No Access

    Article

    Overcoming MDR-associated chemoresistance in HL-60 acute myeloid leukemia cells by targeting shingosine kinase-1

    We examined the involvement of sphingosine kinase-1, a critical regulator of the sphingolipid balance, in susceptibility to antineoplastic agents of either sensitive or multidrug-resistant acute myeloid leukem...

    E Bonhoure, D Pchejetski, N Aouali, H Morjani, T Levade, T Kohama, O Cuvillier in Leukemia (2006)

  4. No Access

    Article

    Apoptosis in serum-deprived vascular smooth muscle cells: Evidence for cell volume-independent mechanism

    Shrinkage is the earliest hallmark of cells undergoing apoptosis. This study examines the role of this phenomenon in the onset of vascular smooth muscle cell (VSMC) apoptosis triggered by growth factor withdra...

    S. N. Orlov, D. Pchejetski, S. Taurin, N. Thorin-Trescases, G. V. Maximov… in Apoptosis (2004)