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Chapter and Conference Paper
Three-Dimensional Strain Calculation of Rubber Composite with Fiber-Shaped Particles by Feature Point Tracking Using X-Ray Computed Tomography
The technique of improving dam** characteristics by complexing fine particles in a viscoelastic material is well-known; however, the relevant underlying mechanism is not yet established. It was found dam**...
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Article
Open AccessRecombinant immunotoxins targeting B-cell maturation antigen are cytotoxic to myeloma cell lines and myeloma cells from patients
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Article
Measurement on Friction Coefficients of Tire Grounding Surface in Arbitrary Directions under High-Load
In order to measure friction coefficients of tire grounding surfaces in car running, a simple cantilever-type tactile sensor that can detect the vertical load and friction force applied to the sensing part as ...
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Article
MUC13 interaction with receptor tyrosine kinase HER2 drives pancreatic ductal adenocarcinoma progression
Although MUC13, a transmembrane mucin, is aberrantly expressed in pancreatic ductal adenocarcinoma (PDAC) and generally correlates with increased expression of HER2, the underlying mechanism remains poorly und...
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Article
Elevation of soluble CD307 (IRTA2/FcRH5) protein in the blood and expression on malignant cells of patients with multiple myeloma, chronic lymphocytic leukemia, and mantle cell lymphoma
CD307 is a differentiation antigen expressed in B-lineage cells. One soluble and two membrane-bound forms have been predicted and an enzyme-linked immunosorbent assay (ELISA) for soluble CD307 established. Our...
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Article
Design and Synthesis of a Novel Organic Triradical as a Model Compound for Generalized Ferrimagnets
We report magnetic properties of novel nitronyl nitroxide triradicals, ptriNN (1) and m-triNN (2), in which a π-conjugated biradical with a singlet ground state and a doublet monoradical are united byσ-bonds of a...
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Article
Magnetic Properties of a Nitronyl Nitroxide Triradical as a Model for Single-Component Molecule-Based Ferrimagnets
Two kinds of organic triradicals consisting of a nitronyl nitroxide biradical with S =1 and a monoradical with S = 1/2 were synthesized as model molecules for single-component organic ferrimagnets. The intramo...
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Article
Ground-State Triplet Biradicals of Nitronyl Nitroxide Containing a Nucleobase Substituent as Synthons for Bio-Inspired Organic Magnets
An organic nitronyl nitroxide biradical substituted with a nucleobase of cytosine was designed and synthesized. The molecular ground state of the biradical was found to be triplet (S = 1) with a singlet-triplet e...
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Article
Building blocks for organic heterospin, heteromolecular complexes as models for organic molecule-based ferrimagnets
Magnetic properties and crystal structure of a pyridine-substituted iminonitroxide biradical, 3,5-bis(4,4,5,5,-tetramethyl-4,5-dihydro-1H-imidazol-2-yl-1-oxyl)pyridine (1), were examined. The molecular ground sta...
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Article
Magnetic properties of a nitronyl nitroxide triradical as a model for single-component molecule-based ferrimagnets
Two kinds of organic triradicals consisting of a nitronyl nitroxide biradical with S=1 and a monoradical with S=1/2 were synthesized as model molecules for single-component organic ferrimagnets. The intramolec...
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Article
Building Blocks for Organic Heterospin, Heteromolecular Complexes as Models for Organic Molecule-Based Ferrimagnets
Magnetic properties and crystal structure of a pyridine-substituted iminonitroxide biradical, 3,5-bis(4,4,5,5,-tetramethyl-4,5-dihydro-1H-imidazol-2-yl-1-oxyl)pyridine (1), were examined. The molecular ground sta...
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Article
Ground-state triplet biradicals of nitronyl nitroxide containing a nucleobase substituent as synthons for bio-inspired organic magnets
An organic nitronyl nitroxide biradical substituted with a nucleobase of cytosine was designed and synthesized. The molecular ground state of the biradical was found to be triplet (S=1) with a singlet-triplet ...
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Article
Design and synthesis of a novel organic triradical as a model compound for generalized ferrimagnets
We report magnetic properties of novel nitronyl nitroxide triradicals, p-triNN (1) and m-triNN (2), in which a π-conjugated biradical with a singlet ground state and a doublet monoradical are united by σ-bonds...
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Article
Roles of Volume-sensitive Cl− Channel in Cisplatin-induced Apoptosis in Human Epidermoid Cancer Cells
The anti-cancer drug cisplatin induces apoptosis by damaging DNA. Since a stilbene-derivative blocker of Cl−/HCO 3 − exchangers and Cl− channels, SITS, is know...
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Article
Clonidine as a drug for intravenous conscious sedation
Clonidine, an α2-adrenoceptor agonist, was introduced to clinical practice in the 1960s because of its antihypertensive effect. It has several beneficial actions during the perioperative period, particularly for...
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Article
Direct interaction of p53 with the Y-box binding protein, YB-1: a mechanism for regulation of human gene expression
The Y-box binding protein, YB-1, belongs to a family of multifunctional proteins which regulate gene expression on both transcriptional and translational levels. The tumor suppressor gene p53 displays growth s...
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Article
Chloralose/ketamine anaesthesia preserves a form of postprandial sodium chloride balance in Wistar rats
Studies on the mechanisms underlying Na balance in anaesthetized rats are complicated by the fact that the most frequently used barbiturate anaesthetics attenuate or abolish this phenomenon. In the present stu...
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Article
Renal effects of manidipine hydrochloride
The renal effects of manidipine hydrochloride were investigated in ten hospitalised patients with mild-to-moderate essential hypertension. After a one-week placebo period, manidipine was given for 1 week in a ...
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Article
Pharmacokinetics of SUN 1165, a new antiarrhythmic agent, in renal dysfunction
The pharmacokinetics of a new Class I antiarrhythmic agent, SUN 1165, has been studied in 32 patients with varying degrees of renal impairment following a single oral dose of 50 mg.
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Article
High-resolution studies in patients with aniridia-Wilms tumor association, Wilms tumor or related congenital abnormalities
We attempted to determine wheter all cases of AWTA (anirida-Wilms tumor association) or any of the following groups of patients show 11p deletion: cases of Wilms tumor with congenital abnormalities other than ...
