15 Result(s)

Article

Does variation of surgical technique affect native tissue anterior pelvic organ prolapse repair outcomes?

The Variation in Surgical Technique study (VaST), demonstrated the large variation in surgical techniques used in native tissue (NT) anterior pelvic organ prolapse (POP) repairs. However, there are few compara...

Emily Fairclough, Julia Segar, Suzanne Breeman… in International Urogynecology Journal (2024)

Article

PROSPECT: 4- and 6-year follow-up of a randomised trial of surgery for vaginal prolapse

Our aim was to compare the mid-term results of native tissue, biological xenograft and polypropylene mesh surgery for women with vaginal wall prolapse.

Fiona M. Reid, Lorna Aucott, Cathryn M. A. Glazener… in International Urogynecology Journal (2023)

Article

Clinical and cost-effectiveness of vaginal pessary self-management compared to clinic-based care for pelvic organ prolapse: protocol for the TOPSY randomised controlled trial

Pelvic organ prolapse (or prolapse) is a common condition in women where the pelvic organs (bladder, bowel or womb) descend into the vagina and cause distressing symptoms that adversely affect quality of life....

Suzanne Hagen, Rohna Kearney, Kirsteen Goodman, Lynn Melone, Andrew Elders… in Trials (2020)

Article

The TOPSY pessary self-management intervention for pelvic organ prolapse: a study protocol for the process evaluation

Process evaluations have become a valued component, alongside clinical trials, of the wider evaluation of complex health interventions. They support understanding of implementation, and fidelity, related to th...

Carol Bugge, Rohna Kearney, Melanie Dembinsky, Aethele Khunda, Margaret Graham… in Trials (2020)

Article

It is unprecedented: trial management during the COVID-19 pandemic and beyond

The COVID-19 pandemic has presented unique challenges for the clinical trial community, both in the rapid establishment of COVID-19 clinical trials and many existing non-COVID-19 studies either being temporari...

Eleanor J. Mitchell, Khaled Ahmed, Suzanne Breeman, Seonaidh Cotton… in Trials (2020)

Article

How to deal with a temporary suspension and restarting your trial: our experiences and lessons learnt

Whilst the issues around early termination of randomised controlled trials (RCTs) are well documented in the literature, trials can also be temporarily suspended with the real prospect that they may subsequent...

Lynda Constable, Tracey Davidson, Suzanne Breeman, Seonaidh Cotton… in Trials (2020)

Article

Using systematic data categorisation to quantify the types of data collected in clinical trials: the DataCat project

Data collection consumes a large proportion of clinical trial resources. Each data item requires time and effort for collection, processing and quality control procedures. In general, more data equals a heavie...

Evelyn Crowley, Shaun Treweek, Katie Banister, Suzanne Breeman, Lynda Constable… in Trials (2020)

Article

Verifying participant-reported clinical outcomes: challenges and implications

Researchers often rely on trial participants to self-report clinical outcomes (for example, fractures, re-operations). Little information exists as to the ‘accuracy’ of participant-reported clinical outcomes, ...

Suzanne Breeman, Lynda Constable, Anne Duncan, Kath Starr, Alison McDonald… in Trials (2020)

Article

HEALTH: laparoscopic supracervical hysterectomy versus second-generation endometrial ablation for the treatment of heavy menstrual bleeding: study protocol for a randomised controlled trial

Heavy menstrual bleeding (HMB) is a common problem affecting approximately 1.5 million women in England and Wales with a major impact on their physical, emotional, social and material quality of life. It is th...

Kevin Cooper, Kirsty McCormack, Suzanne Breeman, Jessica Wood, Neil W. Scott… in Trials (2018)

Article

A UK questionnaire survey of current techniques used to perform pelvic organ prolapse repair

Evidence-based medicine should result in better standardisation of practice. This study aims to evaluate whether there remains variation in surgical techniques in native tissue and graft/mesh repairs of pelvic...

Emily Fairclough, Jenny Myers… in International Urogynecology Journal (2017)

Article

Two parallel, pragmatic, UK multicentre, randomised controlled trials comparing surgical options for upper compartment (vault or uterine) pelvic organ prolapse (the VUE Study): study protocol for a randomised controlled trial

One in three women who have a prolapse operation will go on to have another operation, though not necessarily in the same compartment. Surgery can result in greater impairment of quality of life than the origi...

Cathryn Glazener, Lynda Constable, Christine Hemming, Suzanne Breeman… in Trials (2016)

Article

The importance of rapport and relationship building when recruiting to clinical trials: a qualitative investigation of trial recruitment consultations in a surgical RCT

Lynda Constable, Danielle Pirie, Katie Gillies, Sharon McCann, Suzanne Breeman… in Trials (2015)

Article

Telephone calls to boost response rates in the collection of outcome data

Suzanne Breeman, Seonaidh Cotton, Alison McDonald, Gladys McPherson… in Trials (2013)

Article

Patient reported clinical outcomes: the challenges and implications for randomised controlled trials

Suzanne Breeman, Alison McDonald, Gladys McPherson, Graeme MacLennan… in Trials (2011)