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Open AccessUsing re-randomisation designs to increase the efficiency and applicability of retention studies within trials: a case study
Poor retention in randomised trials can lead to serious consequences to their validity. Studies within trials (SWATs) are used to identify the most effective interventions to increase retention. Many intervent...
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Article
Open AccessCorrection to: Pulpotomy for the Management of Irreversible Pulpitis in Mature Teeth (PIP): a feasibility study
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Article
Open AccessPulpotomy for the Management of Irreversible Pulpitis in Mature Teeth (PIP): a feasibility study
Progression of dental caries can result in irreversible pulpal damage. Partial irreversible pulpitis is the initial stage of this damage, confined to the coronal pulp whilst the radicular pulp shows little or ...
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Article
Examining the impact of oral hygiene advice and/or scale and polish on periodontal disease: the IQuaD cluster factorial randomised controlled trial
Objective To compare the clinical effectiveness and cost benefit of different frequencies of scale and polish (S&P) treatments in combination with different types of oral hygiene advice (OHA).
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Article
Open AccessUsing systematic data categorisation to quantify the types of data collected in clinical trials: the DataCat project
Data collection consumes a large proportion of clinical trial resources. Each data item requires time and effort for collection, processing and quality control procedures. In general, more data equals a heavie...
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Article
Open AccessVerifying participant-reported clinical outcomes: challenges and implications
Researchers often rely on trial participants to self-report clinical outcomes (for example, fractures, re-operations). Little information exists as to the ‘accuracy’ of participant-reported clinical outcomes, ...
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Article
Open AccessEstimating Site Performance (ESP): can trial managers predict recruitment success at trial sites? An exploratory study
Multicentre randomised trials provide some of the key evidence underpinning healthcare practice around the world. They are also hard work and generally expensive. Some of this work and expense are devoted to s...
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Female Performers in the Greco-Roman World: An Introduction
This chapter provides an overview of the performance culture of ancient Greece and the roles played by women around the edges of that culture, before turning to the history of theatre in Rome where women, perf...
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The Roman Mimae: Female Performers in Ancient Rome
Most Roman theatrical entertainments were performed by men and in masks; the major exception to this rule was the genre of mime, which employed actresses to play female roles and did not use masks. Mime was a ...
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Do trial managers know when sites will fail to recruit? Preliminary results from the estimating site performance (ESP) study
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Open AccessImproving trial questionnaire response rates using behaviour change theory
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Open AccessTrials recruiting patients in the acute NHS setting: trial management challenges
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Open AccessWe did it their way, flexible and robust patient recruitment to the IQuaD trial
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Open AccessIQuaD dental trial; improving the quality of dentistry: a multicentre randomised controlled trial comparing oral hygiene advice and periodontal instrumentation for the prevention and management of periodontal disease in dentate adults attending dental primary care
Periodontal disease is the most common oral disease affecting adults, and although it is largely preventable it remains the major cause of poor oral health worldwide. Accumulation of microbial dental plaque is...