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Association of maternal pre-pregnancy or first trimester body mass index with neurodevelopmental impairment or death in extremely low gestational age neonates
To compare the rates of death or survival with severe neurodevelopmental impairment (sNDI) at 2 years among extremely preterm infants in relation to pre-pregnancy or first-trimester maternal body mass index (B...
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Article
Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group in the Pediatric Population
The fundamental gap obstructing forward progress of evidenced-based care in pediatric and neonatal disorders of consciousness (DoC) is the lack of defining consensus-based terminology to perform comparative re...
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Article
Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Goals-of-Care and Family/Surrogate Decision-Maker Data
To facilitate comparative research, it is essential for the fields of neurocritical care and rehabilitation to establish common data elements (CDEs) for disorders of consciousness (DoC). Our objective was to i...
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Article
Relationships between retinopathy of prematurity without ophthalmologic intervention and neurodevelopment and vision at 2 years
Severe retinopathy of prematurity (ROP) is associated with adverse outcomes. Relationships between milder ROP and outcomes have not been defined. We hypothesized that children with ROP stage ≤3 who did not rec...
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Article
Evaluation of heterogeneity in effect of therapeutic hypothermia by sex among infants with neonatal encephalopathy
Our objective was to examine heterogeneity in the effect of therapeutic hypothermia by sex in infants with moderate or severe neonatal encephalopathy.
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Article
Comparative Effectiveness of Surgical Ligation and Catheter Closure of Patent Ductus Arteriosus in Preterm Infants
To evaluate the association, if any, between closure modality (surgical ligation SL vs. catheter CC) of a hemodynamically significant patent ductus arteriosus (PDA), after failure of or contraindication to med...
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Article
Model for severe intracranial hemorrhage and role of early indomethacin in extreme preterm infants
To develop a model for prediction of severe intracranial hemorrhage (ICH) or death based on variables from the first 12 h of age and to compare mortality and morbidities with and without exposure to early indo...
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Article
Effect of an exclusive human milk diet on feeding tolerance in preterm infants
To compare the time to full enteral feeds in preterm infants fed exclusive human milk (EHM) - mother’s own milk (MOM) fortified with human milk-based fortifier (HMBF), to those who received partial human milk ...
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Article
Opioid exposure during therapeutic hypothermia and short-term outcomes in neonatal encephalopathy
To assess the association between opioid exposure during therapeutic hypothermia (TH) for perinatal hypoxic-ischemic encephalopathy (HIE) and in-hospital outcomes.
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Article
Breast milk vs 24% sucrose for procedural pain relief in preterm neonates: a non-inferiority randomized controlled trial
To compare the pain scores between the two groups, breast milk (BM) and 24% sucrose, in preterm neonates undergoing automated heel lance for the blood draw.
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Article
Inter-center variation in autopsy practices among regional neonatal intensive care units (NICUs)
To characterize infants who underwent autopsy in regional neonatal intensive care units (NICUs) and examine inter-center variability in autopsy completion.
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Article
Qualitative indications for tracheostomy and chronic mechanical ventilation in patients with severe bronchopulmonary dysplasia
The decision to pursue chronic mechanical ventilation involves a complex mix of clinical and social considerations. Understanding the medical indications to pursue tracheostomy would reduce the ambiguity for b...
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Article
Withdrawal of artificial nutrition and hydration: a survey of level IV neonatal intensive care units
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Article
Neurodevelopmental outcome of preterm infants enrolled in myo-inositol randomized controlled trial
This study evaluates the 24-month follow-up for the NICHD Neonatal Research Network (NRN) Inositol for Retinopathy Trial.
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Article
Venovenous versus venoarterial extracorporeal membrane oxygenation among infants with hypoxic-ischemic encephalopathy: is there a difference in outcome?
Our hypothesis was that among infants with hypoxic-ischemic encephalopathy (HIE), venoarterial (VA), compared to venovenous (VV), extracorporeal membrane oxygenation (ECMO) is associated with an increased risk...
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Article
Medical and surgical interventions and outcomes for infants with trisomy 18 (T18) or trisomy 13 (T13) at children’s hospitals neonatal intensive care units (NICUs)
To examine characteristics and outcomes of T18 and T13 infants receiving intensive surgical and medical treatment compared to those receiving non-intensive treatment in NICUs.
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Article
In-hospital mortality and morbidity among extremely preterm infants in relation to maternal body mass index
The objective of this paper is to compare in-hospital survival and survival without major morbidities in extremely preterm infants in relation to maternal body mass index (BMI).
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Article
Outcomes of infants with hypoxic ischemic encephalopathy and persistent pulmonary hypertension of the newborn: results from three NICHD studies
To determine the association of persistent pulmonary hypertension of the newborn (PPHN) with death or disability among infants with moderate or severe hypoxic ischemic encephalopathy (HIE) treated with therape...
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Article
Impact of different cord clam** strategies on short term neuromonitoring among preterm infants: a randomized, controlled trial
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Article
Utility of echocardiography in predicting mortality in infants with severe bronchopulmonary dysplasia
To determine the relationship between interventricular septal position (SP) and right ventricular systolic pressure (RVSP) and mortality in infants with severe BPD (sBPD).