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Article
Open AccessT-bet+ B cells are activated by and control endogenous retroviruses through TLR-dependent mechanisms
Endogenous retroviruses (ERVs) are an integral part of the mammalian genome. The role of immune control of ERVs in general is poorly defined as is their function as anti-cancer immune targets or drivers of aut...
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Article
Open AccessQuantitative three-dimensional imaging of chemical short-range order via machine learning enhanced atom probe tomography
Chemical short-range order (CSRO) refers to atoms of specific elements self-organising within a disordered crystalline matrix to form particular atomic neighbourhoods. CSRO is typically characterized indirectl...
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Article
Open AccessBacterial vesicles block viral replication in macrophages via TLR4-TRIF-axis
Gram-negative bacteria naturally secrete nano-sized outer membrane vesicles (OMVs), which are important mediators of communication and pathogenesis. OMV uptake by host cells activates TLR signalling via transp...
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Article
Open AccessA machine learning route between band map** and band structure
The electronic band structure and crystal structure are the two complementary identifiers of solid-state materials. Although convenient instruments and reconstruction algorithms have made large, empirical, cry...
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Article
Open AccessOvercoming barriers to data sharing with medical image generation: a comprehensive evaluation
Privacy concerns around sharing personally identifiable information are a major barrier to data sharing in medical research. In many cases, researchers have no interest in a particular individual’s information...
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Article
Open AccessReal-time prediction of COVID-19 related mortality using electronic health records
Coronavirus disease 2019 (COVID-19) is a respiratory disease with rapid human-to-human transmission caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Due to the exponential growth of ...
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Article
Open AccessConvolutional neural network-assisted recognition of nanoscale L12 ordered structures in face-centred cubic alloys
Nanoscale L12-type ordered structures are widely used in face-centered cubic (FCC) alloys to exploit their hardening capacity and thereby improve mechanical properties. These fine-scale particles are typically fu...
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Article
Open AccessAdjuvant formulated virus-like particles expressing native-like forms of the Lassa virus envelope surface glycoprotein are immunogenic and induce antibodies with broadly neutralizing activity
Lassa mammarenavirus (LASV) is a rodent-borne arenavirus endemic to several West African countries. It is the causative agent of human Lassa fever, an acute viral hemorrhagic fever disease. To date, no therapeuti...
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Article
Open AccessThe Bacterial Product Violacein Exerts an Immunostimulatory Effect Via TLR8
Violacein, an indole-derived, purple-colored natural pigment isolated from Chromobacterium violaceum has shown multiple biological activities. In this work, we studied the effect of violacein in different immune ...
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Article
Open AccessCorrection to: Functional characterization of genes mediating cell wall metabolism and responses to plant cell wall integrity impairment
Following publication of the original article [1], the author reported that the two curves in the sub-diagram WSR4 in Fig. 2a should be the other way round.
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Article
Open AccessFunctional characterization of genes mediating cell wall metabolism and responses to plant cell wall integrity impairment
Plant cell walls participate in all plant-environment interactions. Maintaining cell wall integrity (CWI) during these interactions is essential. This realization led to increased interest in CWI and resulted ...
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Article
Open AccessCorrection to: Metallurgical aspects of joining commercially pure titanium to Ti-6Al-4V alloy in a T-joint configuration by laser beam welding
The article Metallurgical aspects of joining commercially pure titanium to Ti-6Al-4V alloy in a T-joint configuration by laser beam welding by Fedor Fomin, Martin Froend, Volker Ventzke, Pedro Alvarez, Stefan ...
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Article
Open AccessMetallurgical aspects of joining commercially pure titanium to Ti-6Al-4V alloy in a T-joint configuration by laser beam welding
The present paper focuses on the metallurgical and microstructural characterization of the laser beam-welded T-joints between commercially pure titanium (CP-Ti) and Ti-6Al-4V alloy. The weld regions were compr...
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Article
Open AccessCorrection to: Identification and characterization of a galacturonic acid transporter from Neurospora crassa and its application for Saccharomyces cerevisiae fermentation processes
The authors noticed an accidental calculation error existing in Fig. 4C of this article [1]. The given velocities of the GAT-1 transporter (in this figure only) were mistakenly listed 50-fold too high. Based on t...
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Article
Open AccessProgramming mRNA decay to modulate synthetic circuit resource allocation
Synthetic circuits embedded in host cells compete with cellular processes for limited intracellular resources. Here we show how funnelling of cellular resources, after global transcriptome degradation by the s...
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Chapter and Conference Paper
MRI-Based Surgical Planning for Lumbar Spinal Stenosis
The most common reason for spinal surgery in elderly patients is lumbar spinal stenosis (LSS). For LSS, treatment decisions based on clinical and radiological information as well as personal experience of the ...
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Article
Open AccessLignocellulose-derived thin stillage composition and efficient biological treatment with a high-rate hybrid anaerobic bioreactor system
This study aims to chemically characterize thin stillage derived from lignocellulosic biomass distillation residues in terms of organic strength, nutrient, and mineral content. The feasibility of performing an...
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Article
Open AccessClinical Evaluation of a Fully-automatic Segmentation Method for Longitudinal Brain Tumor Volumetry
Information about the size of a tumor and its temporal evolution is needed for diagnosis as well as treatment of brain tumor patients. The aim of the study was to investigate the potential of a fully-automatic...
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Chapter and Conference Paper
Digital Innovation and the Becoming of an Organizational Identity
Today, companies often face rapid and substantial change of their business environment. To stay competitive, firms are forced to engage in continuous innovation of their products and services. Moreover, the di...
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Article
Open AccessEnvironment Has Little Effect on Biomass Biochemical Composition of Miscanthus × giganteus Across Soil Types, Nitrogen Fertilization, and Times of Harvest
Efficient conversion of lignocellulosic feedstocks to ethanol will benefit from a consistent composition of supplied biomass. While composition or quality for a given feedstock is known to vary, the influence ...
