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  1. Article

    Open Access

    Bacterial vesicles block viral replication in macrophages via TLR4-TRIF-axis

    Gram-negative bacteria naturally secrete nano-sized outer membrane vesicles (OMVs), which are important mediators of communication and pathogenesis. OMV uptake by host cells activates TLR signalling via transp...

    Jeff Bierwagen, Marie Wiegand, Katrin Laakmann in Cell Communication and Signaling (2023)

  2. Article

    Open Access

    Adjuvant formulated virus-like particles expressing native-like forms of the Lassa virus envelope surface glycoprotein are immunogenic and induce antibodies with broadly neutralizing activity

    Lassa mammarenavirus (LASV) is a rodent-borne arenavirus endemic to several West African countries. It is the causative agent of human Lassa fever, an acute viral hemorrhagic fever disease. To date, no therapeuti...

    Helena Müller, Sarah Katharina Fehling, Jens Dorna, Richard A. Urbanowicz in npj Vaccines (2020)