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Article
Open AccessSynergistic toxicity with copper contributes to NAT2-associated isoniazid toxicity
Anti-tuberculosis (AT) medications, including isoniazid (INH), can cause drug-induced liver injury (DILI), but the underlying mechanism remains unclear. In this study, we aimed to identify genetic factors that...
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Article
Open AccessInvestigation of blood group genotype prevalence in Korean population using large genomic databases
Blood group antigens, which are prominently expressed in red blood cells, are important in transfusion medicine. The advent of high-throughput genome sequencing technology has facilitated the prediction of blo...
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Article
Open AccessIn vitro erythrocyte production using human-induced pluripotent stem cells: determining the best hematopoietic stem cell sources
Blood transfusion is an essential part of medicine. However, many countries have been facing a national blood crisis. To address this ongoing blood shortage issue, there have been efforts to generate red blood...
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Article
Open AccessIntegrative analysis of multiple genomic data from intrahepatic cholangiocarcinoma organoids enables tumor subty**
As genomic analysis technology has advanced, it has become possible to sub-classify intrahepatic cholangiocarcinoma (ICC) at the histological or molecular level. Here, we verify the recently suggested two subg...
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Article
Open AccessEfficient strategy for the molecular diagnosis of intractable early-onset epilepsy using targeted gene sequencing
We intended to evaluate diagnostic utility of a targeted gene sequencing by using next generation sequencing (NGS) panel in patients with intractable early-onset epilepsy (EOE) and find the efficient analytica...
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Article
Estimation of the flow resistances exerted in coronary arteries using a vessel length-based method
Flow resistances exerted in the coronary arteries are the key parameters for the image-based computer simulation of coronary hemodynamics. The resistances depend on the anatomical characteristics of the corona...
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Article
Open AccessRapidly developed squamous cell carcinoma after laser therapy used to treat chemical burn wound: a case report
In chronic wounds, especially burn scars, malignant tumors can arise. However, it is rare for a subacute burn injury to change to a malignant lesion within one month. Moreover, a case of squamous cell carcinom...
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Article
Open AccessComputational modeling of apoptotic signaling pathways induced by cisplatin
Apoptosis is an essential property of all higher organisms that involves extremely complex signaling pathways. Mathematical modeling provides a rigorous integrative approach for analyzing and understanding suc...
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Article
Erratum to: Antimicrobial Effect of Korean Propolis Against the Mutans Streptococci Isolated from Korean
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Article
Antimicrobial effect of Korean propolis against the mutans streptococci isolated from Korean
The aim of this study was to determine the optimal concentration of Korean propolis against clinical isolates of mutans streptococci (MS) from Koreans. The antimicrobial activity was evaluated using the minimu...
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Chapter and Conference Paper
Computational analysis of the effects of bundle branch blocks in human heart using cardiac cell models
A 3D heart model is proposed to simulate the effect of bundle branch blocks in human heart. This model consists of the ventricle model with the electrophysiological approximation of the cells. The computationa...
