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Article
Open AccessCharacterization of macrophage - cancer cell crosstalk in estrogen receptor positive and triple-negative breast cancer
Tumor heterogeneity may broadly influence the activation of tumor-associated macrophages. We aimed to dissect how breast cancer cells of different molecular characteristics contribute to macrophage phenotype a...
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Article
Open AccessTransgenic overexpression of VEGF-C induces weight gain and insulin resistance in mice
Obesity comprises great risks for human health, contributing to the development of other diseases such as metabolic syndrome, type 2 diabetes and cardiovascular disease. Previously, obese patients were found t...
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Article
Open Access3-hydroxy-L-kynurenamine is an immunomodulatory biogenic amine
Tryptophan catabolism is a major metabolic pathway utilized by several professional and non-professional antigen presenting cells to maintain immunological tolerance. Here we report that 3-hydroxy-l-kynurenamine ...