Page
%P
-
Article
Open AccessOptimizing a mentorship program from the perspective of academic medicine leadership – a qualitative study
Effective mentorship is an important contributor to academic success. Given the critical role of leadership in fostering mentorship, this study sought to explore the perspectives of departmental leadership reg...
-
Article
Open AccessCorrection: Methodology of the SORENTO clinical trial: a prospective, randomised, active-controlled phase 3 trial assessing the efficacy and safety of high exposure octreotide subcutaneous depot (CAM2029) in patients with GEP-NET
-
Article
Open AccessMethodology of the SORENTO clinical trial: a prospective, randomised, active-controlled phase 3 trial assessing the efficacy and safety of high exposure octreotide subcutaneous depot (CAM2029) in patients with GEP-NET
The current standard of care (SoC) for the initial treatment of unresectable or metastatic well-differentiated gastroenteropancreatic neuroendocrine tumours (GEP-NET) requires initiation of first-generation so...
-
Book Series
-
Book and Living Reference Work (Continuously updated edition)
-
Article
Incidence of psychiatric illness in patients with neuroendocrine tumors: a comparative population-based analysis
Diversion of tryptophan to tumoral hormonal production has been suggested to result in psychiatric illnesses in neuroendocrine tumors (NET). We measured the occurrence of psychiatric illness after NET diagnosi...
-
Article
Introducing ‘Anthropocene Science’: A New International Journal for Addressing Human Impact on the Resilience of Planet Earth
-
Article
Analyzing Socio-Metabolic Vulnerability: Evidence from the Comoros Archipelago
Small island develo** states are often characterized as vulnerable owing to their unique geographies of smallness and remoteness, resource insecurity, and more recently from the impacts of climate change. Th...
-
Article
Advanced Pancreatic Neuroendocrine Neoplasms: Which Systemic Treatment Should I Start With?
Pancreatic neuroendocrine neoplasms (panNENs) often present as advanced disease and there is little data to guide treatment sequencing in the advance disease setting. Therefore, we aim to provide a comprehensi...
-
Article
Open AccessTransitions in oral and gut microbiome of HPV+ oropharyngeal squamous cell carcinoma following definitive chemoradiotherapy (ROMA LA-OPSCC study)
Oral and gut microbiomes have emerged as potential biomarkers in cancer. We characterised the oral and gut microbiomes in a prospective observational cohort of HPV+ oropharyngeal squamous cell carcinoma (OPSCC...
-
Article
Open AccessA Budget Impact Model of the Addition of Telotristat Ethyl Treatment to the Standard of Care in Patients with Uncontrolled Carcinoid Syndrome
Carcinoid syndrome, a rare condition in patients with neuroendocrine tumours, characterised by flushing and diarrhoea, severely affects patients’ quality of life. The current carcinoid syndrome standard of car...
-
Article
Impact of diabetes on colorectal cancer stage and mortality risk: a population-based cohort study
Diabetes is associated with an increased incidence of colorectal cancer (CRC). There exists conflicting evidence regarding the impact of diabetes on CRC-specific mortality (herein also referred to as cancer-sp...
-
Article
Open AccessCentromeric cohesion failure invokes a conserved choreography of chromosomal mis-segregations in pancreatic neuroendocrine tumor
Pancreatic neuroendocrine tumors (PANETs) are rare, slow growing cancers that often present with local and distant metastasis upon detection. PANETS contain distinct karyotypes, epigenetic dysregulation, and r...
-
Article
Are We Choosing Surveillance Imaging in Gastric and Pancreatic Cancers Wisely? A Population-Based Study
Although gastric and pancreatic cancers are aggressive, there is no evidence that early detection of recurrence improves overall survival. We aimed to measure the frequency of surveillance imaging in patients ...
-
Chapter
Neuroendocrine Tumors (Gastroenteropancreatic)
With an increasing incidence (per 100,000 population per year) reported in multiple recent population-based studies throughout the world and prolonged survival with disease, neuroendocrine tumors are more prev...
-
Chapter
Therapy for Metastatic Disease: Ileum
The ileum is one of the most common primary sites for neuroendocrine tumours and the most common site of GI NETs. Approximately half will present as locoregionally advanced or metastatic disease. Patients with...
-
Article
Escalated-dose somatostatin analogues for antiproliferative effect in GEPNETS: a systematic review
Somatostatin analogues are the cornerstone of systemic therapy for metastatic well-differentiated gastroenteropancreatic neuroendocrine tumours for both hormonal control and antiproliferative effect. Dose esca...
-
Article
Ki-67 is a reliable pathological grading marker for neuroendocrine tumors
In neuroendocrine tumors (NETs), proliferation markers, especially Ki-67, have become increasingly important. This study was designed to examine the reproducibility of Ki-67 for use in the current classificati...
-
Article
A systematic review of patient surveillance after curative gastrectomy for gastric cancer: a brief review
Complete resection of a gastric cancer and adjacent lymph nodes offers the only chance for cure of the disease. However, disease recurrence occurs in 22–51% of cases, and its prognosis is very poor. Many clini...
-
Article
A systematic review of surgery for non-curative gastric cancer
Most gastric cancer patients present with advanced stage disease precluding curative surgical treatment. These patients may be considered for palliative resection or bypass in the presence of major symptoms; h...
