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Open AccessGut microbiomes of agropastoral children from the Adadle region of Ethiopia reflect their unique dietary habits
The composition and function of the intestinal microbiota are major determinants of human health and are strongly influenced by diet, antibiotic treatment, lifestyle and geography. Nevertheless, we currently h...
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Article
Open AccessDifferent gut microbial communities correlate with efficacy of albendazole-ivermectin against soil-transmitted helminthiases
Soil-transmitted helminth infections represent a large burden with over a quarter of the world’s population at risk. Low cure rates are observed with standard of care (albendazole); therefore, a more effective...
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Article
Open AccessTransitions in oral and gut microbiome of HPV+ oropharyngeal squamous cell carcinoma following definitive chemoradiotherapy (ROMA LA-OPSCC study)
Oral and gut microbiomes have emerged as potential biomarkers in cancer. We characterised the oral and gut microbiomes in a prospective observational cohort of HPV+ oropharyngeal squamous cell carcinoma (OPSCC...
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Article
Open AccessAryl hydrocarbon receptor agonist indigo protects against obesity-related insulin resistance through modulation of intestinal and metabolic tissue immunity
Low-grade chronic inflammation in visceral adipose tissue and the intestines are important drivers of obesity associated insulin resistance. Bioactive compounds derived from plants are an important source of p...
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Article
Open AccessQualitative microbiome profiling along a wastewater system in Kampala, Uganda
Kampala, the capital city of Uganda, is rapidly expanding without adequate wastewater treatment facilities to accommodate the current estimated population of 1.68 million people. Hence, freshwater bodies and n...
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Article
Open AccessMicrobiota analysis optimization for human bronchoalveolar lavage fluid
It is now possible to comprehensively characterize the microbiota of the lungs using culture-independent, sequencing-based assays. Several sample types have been used to investigate the lung microbiota, each p...
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Article
Open AccessInvestigations on the interplays between Schistosoma mansoni, praziquantel and the gut microbiome
Schistosomiasis is a neglected tropical disease burdening millions of people. One drug, praziquantel, is currently used for treatment and control. Clinically relevant drug resistance has not yet been described...
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Open AccessErratum to: Diagnosis of neglected tropical diseases among patients with persistent digestive disorders (diarrhoea and/or abdominal pain ≥14 days): a multi-country, prospective, non-experimental case–control study
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Open AccessDiagnosis of neglected tropical diseases among patients with persistent digestive disorders (diarrhoea and/or abdominal pain ≥14 days): a multi-country, prospective, non-experimental case–control study
Diarrhoea still accounts for considerable mortality and morbidity worldwide. The highest burden is concentrated in tropical areas where populations lack access to clean water, adequate sanitation and hygiene. ...
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Open AccessMicrobial and chemical contamination of water, sediment and soil in the Nakivubo wetland area in Kampala, Uganda
The reuse of domestic and industrial wastewater in urban settings of the develo** world may harm the health of people through direct contact or via contaminated urban agricultural products and drinking water...